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Volumn 107, Issue 11, 2006, Pages 2609-2616

Phase II study of lenalidomide in patients with metastatic renal cell carcinoma

Author keywords

Immunomodulators; Lenalidomide; Phase II; Renal cell carcinoma

Indexed keywords

BEVACIZUMAB; CREATININE; INTERFERON; INTERLEUKIN 2; LENALIDOMIDE; SORAFENIB; SUNITINIB;

EID: 33751565011     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.22290     Document Type: Article
Times cited : (50)

References (43)
  • 3
    • 0033978220 scopus 로고    scopus 로고
    • Systemic therapy for renal cell carcinoma
    • Motzer RJ, Russo P. Systemic therapy for renal cell carcinoma. J Urol. 2000;163:408-417.
    • (2000) J Urol , vol.163 , pp. 408-417
    • Motzer, R.J.1    Russo, P.2
  • 4
    • 7144227930 scopus 로고    scopus 로고
    • Recombinant human interleukin-2, recombinant human interferon alfa-2a, or both in metastatic renal-cell carcinoma
    • Groupe Francais d'Immunotherapie
    • Negrier S, Escudier B, Lasset C, et al. Recombinant human interleukin-2, recombinant human interferon alfa-2a, or both in metastatic renal-cell carcinoma.Groupe Francais d'Immunotherapie. N Engl J Med. 1998;338:1272-1278.
    • (1998) N Engl J Med , vol.338 , pp. 1272-1278
    • Negrier, S.1    Escudier, B.2    Lasset, C.3
  • 5
    • 0033514050 scopus 로고    scopus 로고
    • Interferon-alpha and survival in metastatic renal carcinoma: Early results of a randomised controlled trial
    • [No authors listed.] Medical Research Council Renal Cancer Collaborators
    • [No authors listed.] Interferon-alpha and survival in metastatic renal carcinoma: early results of a randomised controlled trial. Medical Research Council Renal Cancer Collaborators. Lancet. 1999;353:14-17.
    • (1999) Lancet , vol.353 , pp. 14-17
  • 6
    • 0027240519 scopus 로고
    • Identification of the von Hippel-Lindau disease tumor suppressor gene
    • Latif F, Tory K, Gnarra J, et al. Identification of the von Hippel-Lindau disease tumor suppressor gene. Science. 1993;260:1317-1320.
    • (1993) Science , vol.260 , pp. 1317-1320
    • Latif, F.1    Tory, K.2    Gnarra, J.3
  • 7
    • 0027954044 scopus 로고
    • Mutations of the VHL tumour suppressor gene in renal carcinoma
    • Gnarra JR, Tory K, Weng Y, et al. Mutations of the VHL tumour suppressor gene in renal carcinoma. Nat Genet. 1994;7:85-90.
    • (1994) Nat Genet , vol.7 , pp. 85-90
    • Gnarra, J.R.1    Tory, K.2    Weng, Y.3
  • 8
    • 0030834249 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activity
    • Mukhopadhyay D, Knebelmann B, Cohen HT, Ananth S, Sukhatme VP. The von Hippel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activity. Mol Cell Biol. 1997;17:5629-5639.
    • (1997) Mol Cell Biol , vol.17 , pp. 5629-5639
    • Mukhopadhyay, D.1    Knebelmann, B.2    Cohen, H.T.3    Ananth, S.4    Sukhatme, V.P.5
  • 9
    • 27644590918 scopus 로고    scopus 로고
    • Correlation of bFGF expression in renal cell cancer with clinical and histopathological features by tissue microarray analysis and measurement of serum levels
    • Horstmann M, Merseburger AS, von der Heyde E, et al. Correlation of bFGF expression in renal cell cancer with clinical and histopathological features by tissue microarray analysis and measurement of serum levels. J Cancer Res Clin Oncol. 2005;131:715-722.
    • (2005) J Cancer Res Clin Oncol , vol.131 , pp. 715-722
    • Horstmann, M.1    Merseburger, A.S.2    Von Der Heyde, E.3
  • 10
    • 21344435054 scopus 로고    scopus 로고
    • Blocking platelet-derived growth factor-D/platelet-derived growth factor receptor beta signaling inhibits human renal cell carcinoma progression in an orthotopic mouse model
    • Xu L, Tong R, Cochran DM, Jain RK. Blocking platelet-derived growth factor-D/platelet-derived growth factor receptor beta signaling inhibits human renal cell carcinoma progression in an orthotopic mouse model. Cancer Res. 2005;65:5711-5719.
    • (2005) Cancer Res , vol.65 , pp. 5711-5719
    • Xu, L.1    Tong, R.2    Cochran, D.M.3    Jain, R.K.4
  • 11
    • 0042343801 scopus 로고    scopus 로고
    • A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
    • Yang JC, Haworth L, Sherry RM, et al. A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N Engl J Med. 2003;349:427-434.
    • (2003) N Engl J Med , vol.349 , pp. 427-434
    • Yang, J.C.1    Haworth, L.2    Sherry, R.M.3
  • 12
    • 33644833910 scopus 로고    scopus 로고
    • Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma
    • Motzer RJ, Michaelson MD, Redman BG, et al. Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma. J Clin Oncol. 2006;24:16-24.
    • (2006) J Clin Oncol , vol.24 , pp. 16-24
    • Motzer, R.J.1    Michaelson, M.D.2    Redman, B.G.3
  • 14
    • 23944495120 scopus 로고    scopus 로고
    • Thalidomide downregulates angiogenic genes in bone marrow endothelial cells of patients with active multiple myeloma
    • Vacca A, Scavelli C, Montefusco V, et al. Thalidomide downregulates angiogenic genes in bone marrow endothelial cells of patients with active multiple myeloma. J Clin Oncol. 2005;23:5334-5346.
    • (2005) J Clin Oncol , vol.23 , pp. 5334-5346
    • Vacca, A.1    Scavelli, C.2    Montefusco, V.3
  • 15
    • 0041805647 scopus 로고    scopus 로고
    • Thalidomide down-regulates the expression of VEGF and bFGF in cisplatin-resistant human lung carcinoma cells
    • Li X, Liu X, Wang J, et al. Thalidomide down-regulates the expression of VEGF and bFGF in cisplatin-resistant human lung carcinoma cells. Anticancer Res. 2003;23:2481-2487.
    • (2003) Anticancer Res , vol.23 , pp. 2481-2487
    • Li, X.1    Liu, X.2    Wang, J.3
  • 16
    • 0026080801 scopus 로고
    • Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes
    • Sampaio EP, Sarno EN, Galilly R, Cohn ZA, Kaplan G. Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes. J Exp Med. 1991;173:699-703.
    • (1991) J Exp Med , vol.173 , pp. 699-703
    • Sampaio, E.P.1    Sarno, E.N.2    Galilly, R.3    Cohn, Z.A.4    Kaplan, G.5
  • 17
    • 0033980850 scopus 로고    scopus 로고
    • Continuous low dose thalidomide: A phase II study in advanced melanoma, renal cell, ovarian and breast cancer
    • Eisen T, Boshoff C, Mak I, et al. Continuous low dose thalidomide: a phase II study in advanced melanoma, renal cell, ovarian and breast cancer. Br J Cancer. 2000;82:812-817.
    • (2000) Br J Cancer , vol.82 , pp. 812-817
    • Eisen, T.1    Boshoff, C.2    Mak, I.3
  • 18
    • 0036139999 scopus 로고    scopus 로고
    • Phase II trial of thalidomide for patients with advanced renal cell carcinoma
    • Motzer RJ, Berg W, Ginsberg M, et al. Phase II trial of thalidomide for patients with advanced renal cell carcinoma. J Clin Oncol. 2002;20:302-306.
    • (2002) J Clin Oncol , vol.20 , pp. 302-306
    • Motzer, R.J.1    Berg, W.2    Ginsberg, M.3
  • 19
    • 17944362585 scopus 로고    scopus 로고
    • The treatment of advanced renal cell cancer with high-dose oral thalidomide
    • Stebbing J, Benson C, Eisen T, et al. The treatment of advanced renal cell cancer with high-dose oral thalidomide. Br J Cancer. 2001;85:953-958.
    • (2001) Br J Cancer , vol.85 , pp. 953-958
    • Stebbing, J.1    Benson, C.2    Eisen, T.3
  • 21
    • 20144375457 scopus 로고    scopus 로고
    • Orally administered lenalidomide (CC-5013) is anti-angiogenic in vivo and inhibits endothelial cell migration and Akt phosphorylation in vitro
    • Dredge K, Horsfall R, Robinson SP, et al. Orally administered lenalidomide (CC-5013) is anti-angiogenic in vivo and inhibits endothelial cell migration and Akt phosphorylation in vitro. Microvasc Res. 2005;69:56-63.
    • (2005) Microvasc Res , vol.69 , pp. 56-63
    • Dredge, K.1    Horsfall, R.2    Robinson, S.P.3
  • 22
    • 0033168605 scopus 로고    scopus 로고
    • Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha
    • Corral LG, Haslett PA, Muller GW, et al. Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha. J Immunol. 1999;163:380-386.
    • (1999) J Immunol , vol.163 , pp. 380-386
    • Corral, L.G.1    Haslett, P.A.2    Muller, G.W.3
  • 23
    • 0038476461 scopus 로고    scopus 로고
    • Enhancement of cytokine production and AP-1 transcriptional activity in T cells by thalidomide-related immunomodulatory drugs
    • Schafer PH, Gandhi AK, Loveland MA, et al. Enhancement of cytokine production and AP-1 transcriptional activity in T cells by thalidomide-related immunomodulatory drugs. J Pharmacol Exp Ther. 2003;305:1222-1232.
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 1222-1232
    • Schafer, P.H.1    Gandhi, A.K.2    Loveland, M.A.3
  • 24
    • 0035412366 scopus 로고    scopus 로고
    • Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma
    • Davies FE, Raje N, Hideshima T, et al. Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma. Blood. 2001;98:210-216.
    • (2001) Blood , vol.98 , pp. 210-216
    • Davies, F.E.1    Raje, N.2    Hideshima, T.3
  • 25
    • 27744492561 scopus 로고    scopus 로고
    • Combination therapy with lenalidomide plus dexamethasone (Rev/Dex) for newly diagnosed myeloma
    • Rajkumar SV, Hayman SR, Lacy MQ, et al. Combination therapy with lenalidomide plus dexamethasone (Rev/Dex) for newly diagnosed myeloma. Blood. 2005;106:4050-4053.
    • (2005) Blood , vol.106 , pp. 4050-4053
    • Rajkumar, S.V.1    Hayman, S.R.2    Lacy, M.Q.3
  • 26
    • 13444256401 scopus 로고    scopus 로고
    • Efficacy of lenalidomide in myelodysplastic syndromes
    • List A, Kurtin S, Roe DJ, et al. Efficacy of lenalidomide in myelodysplastic syndromes. N Engl J Med. 2005;352:549-557.
    • (2005) N Engl J Med , vol.352 , pp. 549-557
    • List, A.1    Kurtin, S.2    Roe, D.J.3
  • 27
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors
    • European Organization for Research and Treatment of Cancer,-National Cancer Institute of the United States,National Cancer Institute of Canada
    • Therasse P, Arbuck SG, Eisenhauer EA, et al. New guidelines to evaluate the response to treatment in solid tumors.European Organization for Research and Treatment of Cancer,-National Cancer Institute of the United States,National Cancer Institute of Canada. J Natl Cancer Inst. 2000;92:205-216.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3
  • 28
    • 0032772880 scopus 로고    scopus 로고
    • Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma
    • Motzer RJ, Mazumdar M, Bacik J, Berg W, Amsterdam A, Ferrara J. Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma. J Clin Oncol. 1999;17:2530-2540.
    • (1999) J Clin Oncol , vol.17 , pp. 2530-2540
    • Motzer, R.J.1    Mazumdar, M.2    Bacik, J.3    Berg, W.4    Amsterdam, A.5    Ferrara, J.6
  • 29
    • 33644908482 scopus 로고    scopus 로고
    • Randomized phase II study comparing thalidomide with medroxyprogesterone acetate in patients with metastatic renal cell carcinoma
    • Lee CP, Patel PM, Selby PJ, et al. Randomized phase II study comparing thalidomide with medroxyprogesterone acetate in patients with metastatic renal cell carcinoma. J Clin Oncol. 2006;24:898-903.
    • (2006) J Clin Oncol , vol.24 , pp. 898-903
    • Lee, C.P.1    Patel, P.M.2    Selby, P.J.3
  • 31
    • 0035990828 scopus 로고    scopus 로고
    • Phase II trial of thalidomide in renal-cell carcinoma
    • Escudier B, Lassau N, Couanet D, et al. Phase II trial of thalidomide in renal-cell carcinoma. Ann Oncol. 2002;13:1029-1035.
    • (2002) Ann Oncol , vol.13 , pp. 1029-1035
    • Escudier, B.1    Lassau, N.2    Couanet, D.3
  • 32
    • 0037103101 scopus 로고    scopus 로고
    • A pilot study of thalidomide in patients with progressive metastatic renal cell carcinoma
    • Daliani DD, Papandreou CN, Thall PF, et al. A pilot study of thalidomide in patients with progressive metastatic renal cell carcinoma. Cancer. 2002;95:758-765.
    • (2002) Cancer , vol.95 , pp. 758-765
    • Daliani, D.D.1    Papandreou, C.N.2    Thall, P.F.3
  • 33
    • 4644371088 scopus 로고    scopus 로고
    • Low dose interferon-alpha 2b (IFN) + thalidomide (T) in patients (pts) with previously untreated renal cell cancer (RCC): Improvement in progression-free survival (PFS) but not quality of life (QoL) or overall survival (OS)
    • [abstract 4416]
    • Gordon MS, Manola J, Fairclough D, et al. Low dose interferon-alpha 2b (IFN) + thalidomide (T) in patients (pts) with previously untreated renal cell cancer (RCC): improvement in progression-free survival (PFS) but not quality of life (QoL) or overall survival (OS) [abstract 4416]. Proc Am Soc Clin Oncol. 2004;23:384.
    • (2004) Proc Am Soc Clin Oncol , vol.23 , pp. 384
    • Gordon, M.S.1    Manola, J.2    Fairclough, D.3
  • 34
    • 33751583133 scopus 로고    scopus 로고
    • Phase II Study of CC-5013 in patients (pts) with metastatic renal cell cancer (MRCC)
    • [abstract 4604]
    • Rawat A, Needle MN, Miles B, Amato RJ. Phase II Study of CC-5013 in patients (pts) with metastatic renal cell cancer (MRCC) [abstract 4604]. Proc Am Soc Clin Oncol. 2005;23:403s.
    • (2005) Proc Am Soc Clin Oncol , vol.23
    • Rawat, A.1    Needle, M.N.2    Miles, B.3    Amato, R.J.4
  • 35
    • 0037021257 scopus 로고    scopus 로고
    • Novel thalidomide analogues display anti-angiogenic activity independently of immunomodulatory effects
    • Dredge K, Marriott JB, Macdonald CD, et al. Novel thalidomide analogues display anti-angiogenic activity independently of immunomodulatory effects. Br J Cancer. 2002;87:1166-1172.
    • (2002) Br J Cancer , vol.87 , pp. 1166-1172
    • Dredge, K.1    Marriott, J.B.2    Macdonald, C.D.3
  • 36
    • 0037093854 scopus 로고    scopus 로고
    • Protective antitumor immunity induced by a costimulatory thalidomide analog in conjunction with whole tumor cell vaccination is mediated by increased Th1-type immunity
    • Dredge K, Marriott JB, Todryk SM, et al. Protective antitumor immunity induced by a costimulatory thalidomide analog in conjunction with whole tumor cell vaccination is mediated by increased Th1-type immunity. J Immunol. 2002;168:4914-4919.
    • (2002) J Immunol , vol.168 , pp. 4914-4919
    • Dredge, K.1    Marriott, J.B.2    Todryk, S.M.3
  • 37
    • 29244488561 scopus 로고    scopus 로고
    • Immunomodulatory drug lenalidomide (CC-5013, IMiD3) augments anti-CD40 SGN-40-induced cytotoxicity in human multiple myeloma: Clinical implications
    • Tai YT, Li XF, Catley L, et al. Immunomodulatory drug lenalidomide (CC-5013, IMiD3) augments anti-CD40 SGN-40-induced cytotoxicity in human multiple myeloma: clinical implications. Cancer Res. 2005;65:11712-11720.
    • (2005) Cancer Res , vol.65 , pp. 11712-11720
    • Tai, Y.T.1    Li, X.F.2    Catley, L.3
  • 39
    • 0027245920 scopus 로고
    • Hypothyroidism during immunotherapy with interleukin-2 is associated with antithyroid antibodies and response to treatment
    • Weijl NI, Van der Harst D, Brand A, et al. Hypothyroidism during immunotherapy with interleukin-2 is associated with antithyroid antibodies and response to treatment. J Clin Oncol. 1993;11:1376-1383.
    • (1993) J Clin Oncol , vol.11 , pp. 1376-1383
    • Weijl, N.I.1    Van Der Harst, D.2    Brand, A.3
  • 41
    • 0033014677 scopus 로고    scopus 로고
    • Autoimmunity resulting from cytokine treatment predicts long-term survival in patients with metastatic renal cell cancer
    • Franzke A, Peest D, Probst-Kepper M, et al. Autoimmunity resulting from cytokine treatment predicts long-term survival in patients with metastatic renal cell cancer. J Clin Oncol. 1999;17:529-533.
    • (1999) J Clin Oncol , vol.17 , pp. 529-533
    • Franzke, A.1    Peest, D.2    Probst-Kepper, M.3
  • 43
    • 0032741283 scopus 로고    scopus 로고
    • Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function
    • Gabrilovich DI, Ishida T, Nadaf S, Ohm JE, Carbone DP. Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function. Clin Cancer Res. 1999;5:2963-2970.
    • (1999) Clin Cancer Res , vol.5 , pp. 2963-2970
    • Gabrilovich, D.I.1    Ishida, T.2    Nadaf, S.3    Ohm, J.E.4    Carbone, D.P.5


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