Kinetic mechanism of the bifunctional enzyme prostaglandin-H-synthase. Effect of electron donors on the cyclooxygenase reaction

Biochemistry (Moscow)

Volumn 71, Issue 11, 2006, Pages 1247-1255

  Tsaplina, L A ^a   Karatasso, Yu O ^a,b   Filimonov, I S ^a,b   Vrzheshch, P V ^a  

^a MOSCOW STATE UNIVERSITY   (Russian Federation)

^b EMANUEL INSTITUTE OF BIOCHEMICAL PHYSICS   (Russian Federation)

Author keywords

Bifunctional enzyme; Cyclooxygenase activity; Inhibition; Kinetic mechanism; Naproxen; Prostaglandin H synthase; TMPD

Indexed keywords

ALCOHOLS; BIOSYNTHESIS; ENZYME INHIBITION; FATTY ACIDS; HORMONES;

ARACHIDONIC ACID; BIFUNCTIONAL ENZYMES; CYCLOOXYGENASE; ELECTRON DONORS; NAPROXEN; PROSTAGLANDIN;

ENZYME KINETICS;

PEROXIDASE; PROSTAGLANDIN SYNTHASE;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; CATALYSIS; ELECTRON; KINETICS; METABOLISM; OXIDATION REDUCTION REACTION; SHEEP; THEORETICAL MODEL;

ANIMALS; CATALYSIS; ELECTRONS; KINETICS; MODELS, BIOLOGICAL; MODELS, THEORETICAL; OXIDATION-REDUCTION; PEROXIDASE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; SHEEP;

EID: 33751547955     PISSN: 00062979     EISSN: 16083040     Source Type: Journal    
DOI: 10.1134/S0006297906110101     Document Type: Article

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