-
1
-
-
0042709605
-
Molecular mechanisms of amyloidosis
-
Merlini G, Bellotti V. Molecular mechanisms of amyloidosis. N Engl J Med 2003;349:583-596.
-
(2003)
N Engl J Med
, vol.349
, pp. 583-596
-
-
Merlini, G.1
Bellotti, V.2
-
2
-
-
26844559355
-
Inhibition of cathepsin B reduces beta-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: Evidence for cathepsin B as a candidate beta-secretase of Alzheimer's disease
-
Hook V, Toneff T, Bogyo M, Greenbaum D, Medzihradszky KF, Neveu J, et al. Inhibition of cathepsin B reduces beta-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate beta-secretase of Alzheimer's disease. Biol Chem 2005;386:931-940.
-
(2005)
Biol Chem
, vol.386
, pp. 931-940
-
-
Hook, V.1
Toneff, T.2
Bogyo, M.3
Greenbaum, D.4
Medzihradszky, K.F.5
Neveu, J.6
-
3
-
-
22744453951
-
Understanding molecular mechanisms of proteolysis in Alzheimer's disease: Progress toward therapeutic interventions
-
Higuchi M, Iwata N, Saido TC. Understanding molecular mechanisms of proteolysis in Alzheimer's disease: progress toward therapeutic interventions. Biochim Biophys Acta 2005;1751:60-67.
-
(2005)
Biochim Biophys Acta
, vol.1751
, pp. 60-67
-
-
Higuchi, M.1
Iwata, N.2
Saido, T.C.3
-
4
-
-
0033587677
-
Medin: An integral fragment of aortic smooth muscle cell-produced lactadherin forms the most common human amyloid
-
Häggqvist B, Naslund J, Sletten K, Westermark GT, Mucchiano G, Tjernberg LO, et al. Medin: an integral fragment of aortic smooth muscle cell-produced lactadherin forms the most common human amyloid. Proc Natl Acad Sci USA 1999;96:8669-8674.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 8669-8674
-
-
Häggqvist, B.1
Naslund, J.2
Sletten, K.3
Westermark, G.T.4
Mucchiano, G.5
Tjernberg, L.O.6
-
5
-
-
0021710879
-
A variant prealbumin-related low molecular weight amyloid fibril protein in familial amyloid polyneuropathy of Japanese origin
-
Kametani F, Tonoike H, Hoshi A, Shinoda T, Kito S. A variant prealbumin-related low molecular weight amyloid fibril protein in familial amyloid polyneuropathy of Japanese origin. Biochem Biophys Res Commun 1984;125:622-628.
-
(1984)
Biochem Biophys Res Commun
, vol.125
, pp. 622-628
-
-
Kametani, F.1
Tonoike, H.2
Hoshi, A.3
Shinoda, T.4
Kito, S.5
-
6
-
-
0034746557
-
Apolipoprotein A-1-derived amyloid in atherosclerotic plaques of the human aorta
-
Mucchiano GI, Haggqvist B, Sletten K, Westermark P. Apolipoprotein A-1-derived amyloid in atherosclerotic plaques of the human aorta. J Pathol 2001;193:270-275.
-
(2001)
J Pathol
, vol.193
, pp. 270-275
-
-
Mucchiano, G.I.1
Haggqvist, B.2
Sletten, K.3
Westermark, P.4
-
7
-
-
0035125904
-
Apolipoprotein A-I-derived amyloid in atherosclerosis. Its association with plasma levels of apolipoprotein A-I and cholesterol
-
Mucchiano GI, Jonasson L, Haggqvist B, Einarsson E, Westermark P. Apolipoprotein A-I-derived amyloid in atherosclerosis. Its association with plasma levels of apolipoprotein A-I and cholesterol. Am J Clin Pathol 2001;115:298-303.
-
(2001)
Am J Clin Pathol
, vol.115
, pp. 298-303
-
-
Mucchiano, G.I.1
Jonasson, L.2
Haggqvist, B.3
Einarsson, E.4
Westermark, P.5
-
8
-
-
0020697241
-
Frangione B. Primary structure of an amyloid prealbumin variant in familial polyneuropathy of Jewish origin
-
Pras M, Prelli F, Franklin EC, Frangione B. Primary structure of an amyloid prealbumin variant in familial polyneuropathy of Jewish origin. Proc Natl Acad Sci USA 1983;80:539-542.
-
(1983)
Proc Natl Acad Sci USA
, vol.80
, pp. 539-542
-
-
Pras, M.1
Prelli, F.2
Franklin, E.C.3
-
9
-
-
19544366084
-
Proteolysis of serum amyloid A and AA amyloid proteins by cysteine proteases: Cathepsin B generates AA amyloid proteins and cathepsin L may prevent their formation
-
Röcken C, Menard R, Bühling F, Vöckler S, Raynes J, Stix B, et al. Proteolysis of serum amyloid A and AA amyloid proteins by cysteine proteases: cathepsin B generates AA amyloid proteins and cathepsin L may prevent their formation. Ann Rheum Dis 2005;64:808-815.
-
(2005)
Ann Rheum Dis
, vol.64
, pp. 808-815
-
-
Röcken, C.1
Menard, R.2
Bühling, F.3
Vöckler, S.4
Raynes, J.5
Stix, B.6
-
10
-
-
18244404603
-
Hereditary lattice corneal dystrophy is associated with corneal amyloid deposits enclosing C-terminal fragments of kerato-epithelin
-
Stix B, Leber M, Bingemer P, Gross C, Rüschoff J, Fändrich M, et al. Hereditary lattice corneal dystrophy is associated with corneal amyloid deposits enclosing C-terminal fragments of kerato-epithelin. Invest Ophthalmol Vis Sci 2005;46:1133-1139.
-
(2005)
Invest Ophthalmol Vis Sci
, vol.46
, pp. 1133-1139
-
-
Stix, B.1
Leber, M.2
Bingemer, P.3
Gross, C.4
Rüschoff, J.5
Fändrich, M.6
-
11
-
-
0028866543
-
Apolipoprotein A1-derived amyloid in human aortic atherosclerotic plaques
-
Westermark P, Mucchiano G, Marthin T, Johnson KH, Sletten K. Apolipoprotein A1-derived amyloid in human aortic atherosclerotic plaques. Am J Pathol 1995;147:1186-1192.
-
(1995)
Am J Pathol
, vol.147
, pp. 1186-1192
-
-
Westermark, P.1
Mucchiano, G.2
Marthin, T.3
Johnson, K.H.4
Sletten, K.5
-
12
-
-
0036176146
-
Pathology, diagnosis and pathogenesis of AA amyloidosis
-
Röcken C, Shakespeare A. Pathology, diagnosis and pathogenesis of AA amyloidosis. Virchows Arch 2002;440:111-122.
-
(2002)
Virchows Arch
, vol.440
, pp. 111-122
-
-
Röcken, C.1
Shakespeare, A.2
-
13
-
-
0033669024
-
Distribution pattern of matrix metalloproteinases (MMP-1, -2, -3, and -9), tissue inhibitors of matrix metalloproteinases (TIMP-1 and -2), and α2-macroglobulin in cases of generalized AA- and AL amyloidosis
-
Müller D, Roessner A, Röcken C. Distribution pattern of matrix metalloproteinases (MMP-1, -2, -3, and -9), tissue inhibitors of matrix metalloproteinases (TIMP-1 and -2), and α2-macroglobulin in cases of generalized AA- and AL amyloidosis. Virchows Arch 2000;437:521-527.
-
(2000)
Virchows Arch
, vol.437
, pp. 521-527
-
-
Müller, D.1
Roessner, A.2
Röcken, C.3
-
14
-
-
0034886526
-
Proteolysis of AA amyloid fibril proteins by matrix metalloproteinases-1, -2, and -3
-
Stix B, Kähne T, Sletten K, Raynes J, Roessner A, Röcken C. Proteolysis of AA amyloid fibril proteins by matrix metalloproteinases-1, -2, and -3. Am J Pathol 2001;159:561-570.
-
(2001)
Am J Pathol
, vol.159
, pp. 561-570
-
-
Stix, B.1
Kähne, T.2
Sletten, K.3
Raynes, J.4
Roessner, A.5
Röcken, C.6
-
15
-
-
1942435570
-
Cleavage of AL amyloid proteins and AL amyloid deposits by cathepsins B, K, and L
-
Bohne S, Sletten K, Menard R, Bühling F, Vockler S, Wrenger E, et al. Cleavage of AL amyloid proteins and AL amyloid deposits by cathepsins B, K, and L. J Pathol 2004;203:528-537.
-
(2004)
J Pathol
, vol.203
, pp. 528-537
-
-
Bohne, S.1
Sletten, K.2
Menard, R.3
Bühling, F.4
Vockler, S.5
Wrenger, E.6
-
16
-
-
0035099113
-
A putative role for cathepsin K in degradation of AA and AL amyloidosis
-
Röcken C, Stix B, Brömme D, Ansorge S, Roessner A, Bühling F. A putative role for cathepsin K in degradation of AA and AL amyloidosis. Am J Pathol 2001;158:1029-1038.
-
(2001)
Am J Pathol
, vol.158
, pp. 1029-1038
-
-
Röcken, C.1
Stix, B.2
Brömme, D.3
Ansorge, S.4
Roessner, A.5
Bühling, F.6
-
17
-
-
33646544769
-
Prevalence and pathology of amyloid in atherosclerotic arteries
-
Röcken C, Tautenhahn J, Bühling F, Sachwitz D, Vöckler S, Goette A, et al. Prevalence and pathology of amyloid in atherosclerotic arteries. Arterioscler Thromb Vasc Biol 2006;26:676-677.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 676-677
-
-
Röcken, C.1
Tautenhahn, J.2
Bühling, F.3
Sachwitz, D.4
Vöckler, S.5
Goette, A.6
-
18
-
-
0033795691
-
Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis
-
Halangk W, Lerch MM, Brandt-Nedelev B, Roth W, Ruthenbuerger M, Reinheckel T, et al. Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis. J Clin Invest 2000;106:773-781.
-
(2000)
J Clin Invest
, vol.106
, pp. 773-781
-
-
Halangk, W.1
Lerch, M.M.2
Brandt-Nedelev, B.3
Roth, W.4
Ruthenbuerger, M.5
Reinheckel, T.6
-
19
-
-
0032506007
-
Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice
-
Saftig P, Hunziker E, Wehmeyer O, Jones S, Boyde A, Rommerskirch W, et al. Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice. Proc Natl Acad Sci USA 1998;95:13453-13458.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13453-13458
-
-
Saftig, P.1
Hunziker, E.2
Wehmeyer, O.3
Jones, S.4
Boyde, A.5
Rommerskirch, W.6
-
20
-
-
0033810653
-
Cathepsin L deficiency as molecular defect of furless: Hyperproliferation of keratinocytes and pertubation of hair follicle cycling
-
Roth W, Deussing J, Botchkarev VA, Pauly-Evers M, Saftig P, Hafner A, et al. Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and pertubation of hair follicle cycling. FASEB J 2000;14:2075-2086.
-
(2000)
FASEB J
, vol.14
, pp. 2075-2086
-
-
Roth, W.1
Deussing, J.2
Botchkarev, V.A.3
Pauly-Evers, M.4
Saftig, P.5
Hafner, A.6
-
21
-
-
0020549270
-
The kinetics of amyloid deposition. I. The effects of amyloid-enhancing factor and splenectomy
-
Kisilevsky R, Boudreau L. The kinetics of amyloid deposition. I. The effects of amyloid-enhancing factor and splenectomy. Lab Invest 1983;48:53-59.
-
(1983)
Lab Invest
, vol.48
, pp. 53-59
-
-
Kisilevsky, R.1
Boudreau, L.2
-
23
-
-
17744407388
-
Advanced glycation end products and receptor for advanced glycation end products in AA amyloidosis
-
Röcken C, Kientsch-Engel R, Mansfeld S, Stix B, Stubenrauch K, Weigle B, et al. Advanced glycation end products and receptor for advanced glycation end products in AA amyloidosis. Am J Pathol 2003; 162:1213-1220.
-
(2003)
Am J Pathol
, vol.162
, pp. 1213-1220
-
-
Röcken, C.1
Kientsch-Engel, R.2
Mansfeld, S.3
Stix, B.4
Stubenrauch, K.5
Weigle, B.6
-
24
-
-
20944450871
-
Raft lipids as common components of human extracellular amyloid fibrils
-
Gellermann GP, Appel TR, Tannert A, Radestock A, Hortschansky P, Schroeckh V, et al. Raft lipids as common components of human extracellular amyloid fibrils. Proc Natl Acad Sci USA 2005;102:6297-6302.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 6297-6302
-
-
Gellermann, G.P.1
Appel, T.R.2
Tannert, A.3
Radestock, A.4
Hortschansky, P.5
Schroeckh, V.6
-
25
-
-
0037153194
-
Design of noncovalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides
-
Chowdhury SF, Sivaraman J, Wang J, Devanathan G, Lachance P, Qi H, et al. Design of noncovalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides. J Med Chem 2002;45:5321-5329.
-
(2002)
J Med Chem
, vol.45
, pp. 5321-5329
-
-
Chowdhury, S.F.1
Sivaraman, J.2
Wang, J.3
Devanathan, G.4
Lachance, P.5
Qi, H.6
-
26
-
-
0000164586
-
SAA) by murine macrophages in vitro. A light- and electronmicroscopic investigation
-
SAA) by murine macrophages in vitro. A light- and electronmicroscopic investigation. Amyloid 1997;4:259-273.
-
(1997)
Amyloid
, vol.4
, pp. 259-273
-
-
Röcken, C.1
Kisilevsky, R.2
-
27
-
-
0032694091
-
Monoclonal antibody-based sensitive enzyme-linked immunosorbent assay for murine serum amyloid A
-
Yamada T, Fukuda T, Wada A, Itoh Y. Monoclonal antibody-based sensitive enzyme-linked immunosorbent assay for murine serum amyloid A. J Immunoassay 1999;20:223-235.
-
(1999)
J Immunoassay
, vol.20
, pp. 223-235
-
-
Yamada, T.1
Fukuda, T.2
Wada, A.3
Itoh, Y.4
-
28
-
-
0032877133
-
Microextraction and purification techniques applicable to chemical characterization of amyloid proteins in minute amounts of tissue
-
Kaplan B, Hrncic R, Murphy CL, Gallo G, Weiss DT, Solomon A. Microextraction and purification techniques applicable to chemical characterization of amyloid proteins in minute amounts of tissue. Methods Enzymol 1999;309:67-81.
-
(1999)
Methods Enzymol
, vol.309
, pp. 67-81
-
-
Kaplan, B.1
Hrncic, R.2
Murphy, C.L.3
Gallo, G.4
Weiss, D.T.5
Solomon, A.6
-
29
-
-
0034048993
-
Plasmacytoma of the tonsil with AL amyloidosis: Evidence of post-fibrillogenic proteolysis of the fibril protein
-
Röcken C, Hegenbarth V, Schmitz M, Stix B, Schade G, Mohnert A, et al. Plasmacytoma of the tonsil with AL amyloidosis: evidence of post-fibrillogenic proteolysis of the fibril protein. Virchows Arch 2000;436:336-344.
-
(2000)
Virchows Arch
, vol.436
, pp. 336-344
-
-
Röcken, C.1
Hegenbarth, V.2
Schmitz, M.3
Stix, B.4
Schade, G.5
Mohnert, A.6
-
30
-
-
0021326663
-
Monoclonal antibodies against amyloid fibril protein AA. Production, specificity, and use for immunohistochemical localization and classification of AA-type amyloidosis
-
Linke RP. Monoclonal antibodies against amyloid fibril protein AA. Production, specificity, and use for immunohistochemical localization and classification of AA-type amyloidosis. J Histochem Cytochem 1984;32:322-328.
-
(1984)
J Histochem Cytochem
, vol.32
, pp. 322-328
-
-
Linke, R.P.1
-
31
-
-
0029147345
-
High-sensitivity diagnosis of AA amyloidosis using congo red and immunohistochemistry detects missed amyloid deposits
-
Linke RP, Gärtner HV, Michels H. High-sensitivity diagnosis of AA amyloidosis using congo red and immunohistochemistry detects missed amyloid deposits. J Histochem Cytochem 1995;43:863-869.
-
(1995)
J Histochem Cytochem
, vol.43
, pp. 863-869
-
-
Linke, R.P.1
Gärtner, H.V.2
Michels, H.3
-
32
-
-
0034772178
-
Cathepsin K - A marker of macrophage differentiation?
-
Bühling F, Reisenauer A, Gerber A, Krüger S, Weber E, Brömme D, et al. Cathepsin K - a marker of macrophage differentiation?. J Pathol 2001;195:375-382.
-
(2001)
J Pathol
, vol.195
, pp. 375-382
-
-
Bühling, F.1
Reisenauer, A.2
Gerber, A.3
Krüger, S.4
Weber, E.5
Brömme, D.6
-
33
-
-
0035822274
-
Amyloid load and clinical outcome in AA amyloidosis in relation to circulating concentration of serum amyloid A protein
-
Gillmore JD, Lovat LB, Persey MR, Pepys MB, Hawkins PN. Amyloid load and clinical outcome in AA amyloidosis in relation to circulating concentration of serum amyloid A protein. Lancet 2001;358:24-29.
-
(2001)
Lancet
, vol.358
, pp. 24-29
-
-
Gillmore, J.D.1
Lovat, L.B.2
Persey, M.R.3
Pepys, M.B.4
Hawkins, P.N.5
-
34
-
-
0033548474
-
The heparin/heparan sulfate-binding site on apo serum amyloid A - Implications for the therapeutic intervention of amyloidosis
-
Ancsin JB, Kisilevsky R. The heparin/heparan sulfate-binding site on apo serum amyloid A - implications for the therapeutic intervention of amyloidosis. J Biol Chem 1999;274:7172-7181.
-
(1999)
J Biol Chem
, vol.274
, pp. 7172-7181
-
-
Ancsin, J.B.1
Kisilevsky, R.2
-
35
-
-
14644411088
-
Carboxy-monopeptidase substrate specificity of human cathepsin X
-
Devanathan G, Turnbull JL, Ziomek E, Purisima EO, Menard R, Sulea T. Carboxy-monopeptidase substrate specificity of human cathepsin X. Biochem Biophys Res Commun 2005;329:445-452.
-
(2005)
Biochem Biophys Res Commun
, vol.329
, pp. 445-452
-
-
Devanathan, G.1
Turnbull, J.L.2
Ziomek, E.3
Purisima, E.O.4
Menard, R.5
Sulea, T.6
-
36
-
-
9444263075
-
Amyloidogenesis recapitulated in cell culture: A peptide inhibitor provides direct evidence for the role of heparan sulfate and suggests a new treatment strategy
-
Elimova E, Kisilevsky R, Szarek WA, Ancsin JB. Amyloidogenesis recapitulated in cell culture: a peptide inhibitor provides direct evidence for the role of heparan sulfate and suggests a new treatment strategy. FASEB J 2004;18:1749-1751.
-
(2004)
FASEB J
, vol.18
, pp. 1749-1751
-
-
Elimova, E.1
Kisilevsky, R.2
Szarek, W.A.3
Ancsin, J.B.4
-
37
-
-
0028913416
-
Arresting amyloidosis in vivo using small-molecule anionic sulphonates or sulphates: Implications for Alzheimer's disease
-
Kisilevsky R, Lemieux LJ, Fraser PE, Kong X, Hultin PG, Szarek WA. Arresting amyloidosis in vivo using small-molecule anionic sulphonates or sulphates: implications for Alzheimer's disease. Nature Med 1995;1:143-148.
-
(1995)
Nature Med
, vol.1
, pp. 143-148
-
-
Kisilevsky, R.1
Lemieux, L.J.2
Fraser, P.E.3
Kong, X.4
Hultin, P.G.5
Szarek, W.A.6
-
38
-
-
0347753241
-
Macrophage cholesterol efflux and the active domains of serum amyloid A 2.1
-
Kisilevsky R, Tam SP. Macrophage cholesterol efflux and the active domains of serum amyloid A 2.1. J Lipid Res 2003;44:2257-2269.
-
(2003)
J Lipid Res
, vol.44
, pp. 2257-2269
-
-
Kisilevsky, R.1
Tam, S.P.2
-
39
-
-
0036737704
-
Promoting export of macrophage cholesterol: The physiological role of a major acute-phase protein, serum amyloid A 2.1
-
Tam SP, Flexman A, Hulme J, Kisilevsky R. Promoting export of macrophage cholesterol: the physiological role of a major acute-phase protein, serum amyloid A 2.1. J Lipid Res 2002;43:1410-1420.
-
(2002)
J Lipid Res
, vol.43
, pp. 1410-1420
-
-
Tam, S.P.1
Flexman, A.2
Hulme, J.3
Kisilevsky, R.4
-
40
-
-
0024460772
-
Massive vascular AA-amyloidosis: A histologically and biochemically distinctive subtype of reactive systemic amyloidosis
-
Westermark GT, Sletten K, Westermark P. Massive vascular AA-amyloidosis: a histologically and biochemically distinctive subtype of reactive systemic amyloidosis. Scand J Immunol 1989;30:605-613.
-
(1989)
Scand J Immunol
, vol.30
, pp. 605-613
-
-
Westermark, G.T.1
Sletten, K.2
Westermark, P.3
-
42
-
-
0026447176
-
Identification of two novel amyloid A protein subsets coexisting in an individual patient of AA-amyloidosis
-
Baba S, Takahashi T, Kasama T, Shirasawa H. Identification of two novel amyloid A protein subsets coexisting in an individual patient of AA-amyloidosis. Biochim Biophys Acta 1992;1180:195-200.
-
(1992)
Biochim Biophys Acta
, vol.1180
, pp. 195-200
-
-
Baba, S.1
Takahashi, T.2
Kasama, T.3
Shirasawa, H.4
-
44
-
-
0015419122
-
The amino acid sequence of a major nonimmunoglobulin component of some amyloid fibrils
-
Levin M, Franklin EC, Frangione B, Pras M. The amino acid sequence of a major nonimmunoglobulin component of some amyloid fibrils. J Clin Invest 1972;51:2773-2776.
-
(1972)
J Clin Invest
, vol.51
, pp. 2773-2776
-
-
Levin, M.1
Franklin, E.C.2
Frangione, B.3
Pras, M.4
-
45
-
-
0023183990
-
Amyloid fibril protein AA. Characterization of uncommon subspecies from a patient with rheumatoid arthritis
-
Westermark GT, Westermark P, Sletten K. Amyloid fibril protein AA. Characterization of uncommon subspecies from a patient with rheumatoid arthritis. Lab Invest 1987;57:57-64.
-
(1987)
Lab Invest
, vol.57
, pp. 57-64
-
-
Westermark, G.T.1
Westermark, P.2
Sletten, K.3
|