Kleine-Levin syndrome in a 14-year-old girl: CSF hypocretin-1 measurements

Sleep Medicine

Volumn 7, Issue 8, 2006, Pages 649-651

  Podestá, Claudio ^a   Ferreras, Mónica ^b   Mozzi, Marcela ^b   Bassetti, Claudio ^c   Dauvilliers, Yves ^d   Billiard, Michel ^d  

^a FLENI   (Argentina)

^b Neuraxis Sleeplab ^*  (Argentina)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^d GUI DE CHAULIAC HOSPITAL   (France)

Author keywords

CSF hypocretin 1; Kleine Levin syndrome; Recurrent hypothalamic dysfunction

Indexed keywords

CARBAMAZEPINE; METHYLPHENIDATE; MODAFINIL; OREXIN; VALPROIC ACID;

ADOLESCENT; AMNESIA; ARTICLE; CASE REPORT; COGNITIVE DEFECT; DISEASE SEVERITY; FEMALE; HUMAN; HYPERPHAGIA; HYPERSEXUALITY; HYPERSOMNIA; POLYSOMNOGRAPHY; PRIORITY JOURNAL; PROTEIN CEREBROSPINAL FLUID LEVEL; RADIOIMMUNOASSAY; REM SLEEP; SLEEP PATTERN; SLEEP TIME; SYMPTOMATOLOGY;

ADOLESCENT; FEMALE; HUMANS; HYPOTHALAMUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KLEINE-LEVIN SYNDROME; NEUROPEPTIDES;

EID: 33751425459     PISSN: 13899457     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.sleep.2006.07.003     Document Type: Article

References (8)

1. Critchley M. Periodic hypersomnia and megaphagia in adolescent males. Brain 85 (1962) 627-656
2. Dauvilliers Y., Mayer G., Lecendreux M., Neidhart E., Peraita-Adrados R., Sonka K., et al. Kleine-Levin syndrome. An autoimmune hypothesis based on clinical and genetic analyses. Neurology 59 (2003) 1739-1745
3. de Lecea L., Kilduff T.S., Peyron C., Gao X.-B., Foye P.E., Danielson P.E., et al. The hypocretins : hypothalamus specific peptides with neuroexcitatory activity. Proc Natl Acad Sci USA 95 (1998) 322-327
4. Sakurai T., Amemiya A., Ishii M., Matsuzaki I., Chemelli R.M., Tanaka H., et al. Orexins and orexin receptors : a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 92 (1998) 573-585
5. De Lecea L, Winsky-Sommerer R, Paneda C, Suzuki C, Sutcliffe JG. The hypocretins (not hypocretines): discovery and emerging role as integrators of physiological signals. In: Bassetti C, Billiard M, Mignot E. (Eds.) Narcolepsy and Hypersomnia. Marcel Dekker, New York, in press.
6. Nishino S., Ripley B., Overeem S., Nevsimalova S., Lammers G.J., Vankova J., et al. Low CSF hypocretin (orexin) and altered energy homeostasis in human narcolepsy. Ann Neurol 50 (2001) 381-388
7. Mignot E., Lammers G.J., Ripley B., Okun M., Nevsimalova S., Overeem S., et al. The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias. Arch Neurol 59 (2002) 1553-1562
8. Katz J.D., and Ropper A.H. Familial Kleine-Levin syndrome: two siblings with unusually long hypersomnic spells. Arch Neurol 59 (2002) 1959-1961