Striking differences of action of lisuride stereoisomers at histamine H1 receptors

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 374, Issue 3, 2006, Pages 215-222

  Pertz, Heinz H ^a   Görnemann, Tilo ^a   Schurad, Björn ^b   Seifert, Roland ^c   Straßer, Andrea ^c  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b NeuroBiotec GmbH   (Germany)

^c UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

8R Lisuride; 8S Lisuride; Antiparkinsonian drugs; Dopamine receptor agonist; Histamine H1 receptor

Indexed keywords

1 ALLYLLISURIDE; 1,1 DIETHYL 3 (9,10 DIDEHYDRO 6 METHYL 8ALPHA ERGOLINYL)UREA HYDROGEN MALEATE; 1,1 DIETHYL 3 (9,10 DIDEHYDRO 6 METHYL 8BETA ERGOLINYL)UREA; ANTIPARKINSON AGENT; BROMOCRIPTINE; CABERGOLINE; DOPAMINE RECEPTOR STIMULATING AGENT; ERGOLINE DERIVATIVE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; HISTAMINE; HISTAMINE H1 RECEPTOR; HISTAMINE H1 RECEPTOR ANTAGONIST; LISURIDE; MEPYRAMINE; PERGOLIDE; RADIOLIGAND; TERGURIDE; TRITIUM; UNCLASSIFIED DRUG;

AFFINITY LABELING; AGONIST; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN; CELL MEMBRANE; CONTROLLED STUDY; DOPAMINERGIC TRANSMISSION; DRUG BINDING; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; ENZYME ACTIVITY; GUINEA PIG; ILEUM; INSECT CELL; MALE; MUSCLE CONTRACTILITY; NONHUMAN; PROTEIN EXPRESSION; STEREOISOMERISM;

ANIMALS; ANTIPARKINSON AGENTS; CELL MEMBRANE; DOPAMINE; DOPAMINE AGONISTS; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GUINEA PIGS; HUMANS; ILEUM; INSECTS; LISURIDE; MALE; MUSCLE CONTRACTION; PARKINSON DISEASE; PYRILAMINE; RECEPTORS, HISTAMINE H1; RGS PROTEINS; SPECIES SPECIFICITY; STEREOISOMERISM;

EID: 33751421293     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-006-0111-0     Document Type: Article

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