Ternary complex formation of Ino2p-Ino4p transcription factors and Apl2p adaptin β subunit in yeast

Bioscience, Biotechnology and Biochemistry

Volumn 70, Issue 11, 2006, Pages 2604-2612

  Nikawa, Jun Ichi ^a   Yata, Masako ^a   Motomura, Miki ^a   Miyoshi, Nobutaka ^a   Ueda, Tsuyoshi ^a   Hisada, Daisuke ^a  

^a KYUSHU INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Adaptin; Carbon source; Inositol biosynthesis; Oxidative stress; Transcriptional regulation

Indexed keywords

BIOSYNTHESIS; CARBON; CELLS; FERMENTATION; GENES; GLYCOLS; OXIDATION;

ADAPTINS; CARBON SOURCES; CHOLINES; OXIDATIVE STRESSES; TRANSCRIPTIONAL REGULATION;

YEAST;

APL2 PROTEIN, S CEREVISIAE; BETA ADAPTIN; CARBON; CLATHRIN; HYDROGEN PEROXIDE; INO2 PROTEIN, S CEREVISIAE; INO4 PROTEIN, S CEREVISIAE; PROTEIN SUBUNIT; REPRESSOR PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; OXIDATIVE STRESS; PHENOTYPE; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE; TWO HYBRID SYSTEM;

ADAPTOR PROTEIN COMPLEX BETA SUBUNITS; CARBON; CLATHRIN; GENE EXPRESSION REGULATION, FUNGAL; HYDROGEN PEROXIDE; OXIDATIVE STRESS; PHENOTYPE; PROTEIN BINDING; PROTEIN SUBUNITS; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 33751419240     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.60146     Document Type: Article

References (27)

1. +) cells. J. Bacteriol., 126, 232-242 (1976).
2. Dean-Johnson, M., and Henry, S., Biosynthesis of inositol in yeast: primary structure of myo-inositol-1-phosphate synthase (EC 5.5.1.4) and functional analysis of its structural gene, the INO1 locus. J. Biol. Chem., 264, 1274-1283 (1989).
3. Nikawa, J., Tsukagoshi, Y., and Yamashita, S., Isolation and characterization of two distinct myo-inositol transport genes of Saccharomyces cerevisiae. J. Biol. Chem., 266, 11184-11191 (1991).
4. Kodaki, T., Hosaka, K., Nikawa, J., and Yamashita, S., Identification of the upstream activation sequences responsible for the expression and regulation of the PEM1 and PEM2 genes encoding the enzymes of the phosphatidylethanolamine methylation pathway in Saccharomyces cerevisiae. J. Biochem., 109, 276-287 (1991).
5. Lopes, J. M., Hirsch, J. P., Chorgo, P. A., Schulze, K. L., and Henry, S. A., Analysis of sequences in the INO1 promoter that are involved in its regulation by phospholipid precursors. Nucleic Acids Res., 19, 1687-1693 (1991).
6. Ambroziak, J., and Henry, S. A., INO2 and INO4 gene products, positive regulators of phospholipid biosynthesis in Saccharomyces cerevisiae, form a complex that binds to the INO1 promoter. J. Biol. Chem., 269, 15344-15349 (1994).
7. Schwank, S., Ebbert, R., Bautenstrauss, K., Schweizer, E., and Schuller, H.-J., Yeast transcriptional activator INO2 interacts as an Ino2p/Ino4p basic helix-loop-helix heteromeric complex with the inositol/choline-responsive element necessary for expression of phospholipid biosynthetic genes in Saccharomyces cerevisiae. Nucleic Acids Res., 23, 230-237 (1995).
8. Ashburner, B. P., and Lopes, J. M., Autoregulated expression of the yeast INO2 and INO4 helix-loop-helix activator genes effects cooperative regulation on their target genes. Mol. Cell. Biol., 15, 1709-1715 (1995).
9. Greenberg, M. L., Reiner, B., and Henry, S. A., Regulatory mutations of inositol biosynthesis in yeast: isolation of inositol-excreting mutants. Genetics, 100, 19-33 (1982).
10. Loewen, C. J. R., Gaspar, M. L., Jesch, S. A., Delon, C., Ktistakis, N. T., Henry, S. A., and Levine, T. P., Phospholipid metabolism regulated by a transcription factor sensing phosphatidic acid. Science, 304, 1644-1647 (2004).
11. Uetz, P., Giot, L., Cagney, G., Mansfield, T. A., Judson, R. S., Knight, J. R., Lockshon, D., Narayan, V., Srinivasan, M., Pochart, P., Qureshi-Emili, A., Li, Y., Godwin, B., Conover, D., Kalbfleisch, T., Vijayadamodar, G., Yang, M., Johnston, M., Fields, S., and Rothberg, J. M., A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature, 403, 623-627 (2000).
12. Boehm, M., and Bonifacino, J. S., Adaptins: the final recount. Mol. Biol. Cell, 12, 2907-2920 (2001).
13. Rad, M. R., Phan, H. L., Kirchrath, L., Tan, P. K., Kirchhausen, T., Hollenberg, C. P., and Payne, G. S., Saccharomyces cerevisiae Apl2p, a homologue of the mammalian clathrin AP β subunit, plays a role in clathrin-dependent Golgi functions. J. Cell Sci., 108, 1605-1615 (1995).
14. Boehm, M., and Bonifacino, J. S., Genetic analysis of adaptin function from yeast to mammals. Gene, 286, 175-186 (2002).
15. Yeung, B. G., and Payne, G. S., Clathrin interactions with C-terminal regions of the yeast AP-1 β and γ subunits are important for AP-1 association with clathrin coats. Traffic, 2, 565-576 (2001).
16. Dell'Angelica, E. C., Klumperman, J., Stoorvogel, W., and Bonifacino, J. S., Association of the AP-3 adaptor complex with clathrin. Science, 280, 431-434 (1998).
17. Sambrook, J., Fritsch, F. H., and Maniatis, T., "Molecular Cloning, a Laboratory Manual" 2nd ed., Cold Spring Harbor Laboratory, Cold Spring Harbor (1989).
18. Yamashita, S., and Oshima, A., Regulation of phosphatidylethanolamine methyltransferase level by myo-inositol in Saccharomyces cerevisiae. Eur. J. Biochem., 104, 611-616 (1980).
19. Ito, H., Fukuda, Y., Murata, K., and Kimura, A., Transformation of intact yeast cells treated with alkali cations. J. Bacteriol., 153, 163-168 (1983).
20. Nikawa, J., and Kawabata, M., PCR- and ligation-mediated synthesis of marker cassettes with long flanking homology regions for gene disruption in Saccharomyces cerevisiae. Nucleic Acids Res., 26, 860-861 (1998).
21. Hosaka, K., Nikawa, J., Kodaki, T., and Yamashita, S., A dominant mutation that alters the regulation of INO1 expression in Saccharomyces cerevisiae. J. Biochem., 111, 352-358 (1992).
22. Nikawa, J., and Hosaka, K., Isolation and characterization of genes that promote the expression of inositol transporter gene ITR1 in Saccharomyces cerevisiae. Mol. Microbiol., 10, 955-961 (1995).
23. Miyashita, M., Syugyo, M., and Nikawa, J., Mutational analysis and location of the inositol transporters of Saccharomyces cerevisiae. J. Biosci. Bioeng., 96, 291-297 (2003).
24. Jamieson, D. J., Oxidative stress responses of the yeast Saccharomyces cerevisiae. Yeast, 14, 1511-1527 (1998).
25. Temple, M. D., Perrone, G. G., and Dawes, I. W., Complex cellular responses to reactive oxygen species. Trends Cell. Biol., 15, 319-326 (2005).
26. Ikner, A., and Shiozaki, K., Yeast signaling pathways in the oxidative stress response. Mutat. Res., 569, 13-27 (2005).
27. Thorpe, G. W., Fong, C. S., Alic, N., Higgins, V. J., and Dawes, I. W., Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes. Proc. Natl. Acad. Sci. USA, 101, 6564-6569 (2004).