Fertility sparing therapy in a patient with placental site trophoblastic tumor: A case report

Gynecologic Oncology

Volumn 103, Issue 3, 2006, Pages 1141-1143

  Numnum, T Michael ^a   Kilgore, Larry C ^a   Conner, Michael G ^b   Straughn Jr , J Michael ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b University of Alabama at Birmingham   (United States)

Author keywords

Chemotherapy; Gestational trophoblastic disease; Placental site trophoblastic tumor

Indexed keywords

CHORIONIC GONADOTROPIN; CISPLATIN; DACTINOMYCIN; ETOPOSIDE; FOLINIC ACID; METHOTREXATE; ORAL CONTRACEPTIVE AGENT;

ADULT; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CASE REPORT; CHILDBIRTH; FEMALE; FEMALE INFERTILITY; HORMONE BLOOD LEVEL; HUMAN; MULTIPLE CYCLE TREATMENT; PLACENTAL SITE TROPHOBLASTIC TUMOR; PRIORITY JOURNAL; TROPHOBLASTIC TUMOR; VAGINA BLEEDING;

ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; COMBINED MODALITY THERAPY; CURETTAGE; DIAGNOSIS, DIFFERENTIAL; FEMALE; FERTILITY; HUMANS; PREGNANCY; TROPHOBLASTIC TUMOR, PLACENTAL SITE; UTERINE NEOPLASMS;

EID: 33751395686     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2006.07.039     Document Type: Article

References (9)

1. Kurman R.J., Scully R.E., and Norris H.J. Trophoblastic pseudotumor of the uterus: an exaggerated form of "syncytial endometritis" simulating a malignant tumor. Cancer 38 3 (1976) 1214-1226
2. Scully R.E., and Young R.H. Trophoblastic pseudotumor: a reappraisal. Am. J. Surg. Pathol. 5 1 (1981) 75-76
3. Feltmate C.M., Genest D.R., Wise L., et al. Placental site trophoblastic tumor: a 17-year experience at the New England trophoblastic disease center. Gynecol. Oncol. 82 3 (2001) 415-419
4. Baergen R.N., Rutgers J.L., Young R.H., et al. Placental site trophoblastic tumor: a study of 55 cases and review of the literature emphasizing factors of prognostic significance. Gynecol. Oncol. 100 3 (2006) 511-520
5. Newlands E.S., Mulholland P.J., Holden L., Seckl M.J., and Rustin G.J.S. Etoposide and cisplatin/etoposide, methotrexate, and actinomycin D (EMA) chemotherapy for patients with high-risk gestational trophoblastic tumors refractory to EMA/cyclophosphamide and vincristine chemotherapy and patients presenting with metastatic placental site trophoblastic tumors. J. Clin. Oncol. 18 4 (2000) 854-859
6. Tsuji Y., Tsubamoto H., Hori M., Ogasawara T., and Koyama K. Case of PSTT treated with chemotherapy followed by open uterine tumor resection to preserve fertility. Gynecol. Oncol. 87 3 (2002) 303-307
7. Machtinger R., Gotlieb W.H., Korach J., et al. Placental site trophoblastic tumor: outcome of five cases including fertility preserving management. Gynecol. Oncol. 96 1 (2005) 56-61
8. Leiserowitz G.S., and Webb M.J. Treatment of placental site trophoblastic tumor with hysterotomy and uterine reconstruction. Obstet. Gynecol. 88 4 Pt 2 (1996) 696-699
9. Waxman J. Chemotherapy and the adult gonad: a review. J. R. Soc. Med. 76 2 (1983) 144-148