Strain-dependent expression of four structurally related rat Ly49 receptors; correlation with NK gene complex haplotype and NK alloreactivity

Immunogenetics

Volumn 58, Issue 11, 2006, Pages 905-916

  Kveberg, Lise ^a   Dai, Ke Zheng ^a   Dissen, Erik ^a   Ryan, James C ^b   Rolstad, Bent ^a   Vaage, John T ^a   Naper, Christian ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alloreactivity; Ly49 receptors; MHC; Natural Killer cells; Rodent

Indexed keywords

LY49 STIMULATORY RECEPTOR 3; LY49 STIMULATORY RECEPTOR 4; RECEPTOR; UNCLASSIFIED DRUG;

ALLOIMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOLYSIS; GENE EXPRESSION; HAPLOTYPE; LYMPHOCYTE; MAJOR HISTOCOMPATIBILITY COMPLEX; NATURAL KILLER CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, LY; HAPLOTYPES; HISTOCOMPATIBILITY ANTIGENS CLASS I; KILLER CELLS, NATURAL; LECTINS, C-TYPE; LIGANDS; MOLECULAR SEQUENCE DATA; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RATS;

RODENTIA;

EID: 33751368861     PISSN: 00937711     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00251-006-0154-x     Document Type: Article

References (31)

1. Arase H, Mocarski ES, Campbell AE, Hill AB, Lanier LL (2002) Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors. Science 296:1323-1326
2. Berg SF, Dissen E, Westgaard IH, Fossum S (1998a) Molecular characterization of rat NKR-P2, a lectin-like receptor expressed by NK cells and resting T cells. Int Immunol 10:379-385
3. Berg SF, Dissen E, Westgaard IH, Fossum S (1998b) Two genes in the rat homologous to human NKG2. Eur J Immunol 28:444-450
4. Carlyle JR, Mesci A, Ljutic B, Belanger S, Tai L-H, Rousselle E, Troke AD, Proteau M-F, Makrigiannis AP (2006) Molecular and genetic basis for strain-dependent NK1.1 alloreactivity of mouse NK cells. J Immunol 176:7511-7524
5. Dissen E, Vaage JT, Taskén K, Jahnsen T, Rolstad B, Fossum S (1990) Alloreactive lymphokine-activated killer cells from athymic nude rats do not express CD3-associated α/β or γ/δ T cell receptors. Int Immunol 2:453-460
6. Dissen E, Ryan JC, Seaman WE, Fossum S (1996) An autosomal dominant locus, Nka, mapping to the Ly-49 region of a rat natural killer (NK) gene complex, controls NK cell lysis of allogeneic lymphocytes. J Exp Med 183:2197-2207
7. Dissen E, Berg SF, Westgaard IH, Fossum S (1997) Molecular characterization of a gene in the rat homologous to human CD94. Eur J Immunol 27:2080-2086
8. Heslop BF (1994) Allogeneic lymphocyte cytotoxicity (ALC) in rats: allogeneic recognition vs. failed self recognition. In: B. Rolstad, ed. Natural immunity to normal hemopoietic cells. CRC Press, Boca Raton, FL, pp 1-32
9. Kane KP, Silver ET, Hazes B (2001) Specificity and function of activating Ly-49 receptors. Immunol Rev 181:104-114
10. Kveberg L, Bäck CJ, Dai K-Z, Inngjerdingen M, Rolstad B, Ryan JC, Vaage JT, Naper C (2006) The novel inhibitory NKR-P1C receptor and Ly49s3 identify two complementary, functionally distinct NK cell subsets in rats. J Immunol 176:4133-4140
11. Løvik G, Vaage JT, Naper C, Benestad HB, Rolstad B (1995) Recruitment of alloreactive natural killer cells to the rat peritoneum by a transfected cell line secreting rat recombinant interleukin-2. J Immunol Methods 179:59-69
12. McMahon CW, Raulet DH (2001) Expression and function of NK cell receptors in CD8+ T cells. Curr Opin Immunol 13:465-470
13. Nakamura MC, Naper C, Niemi EC, Spusta SC, Rolstad B, Butcher GW, Seaman WE, Ryan JC (1999) Natural killing of xenogeneic cells mediated by the mouse Ly-49D receptor. J Immunol 163:4694-4700
14. Naper C, Vaage JT, Lambracht D, Løvik G, Butcher GW, Wonigeit K, Rolstad B (1995) Alloreactive natural killer cells in the rat: complex genetics of major histocompatibility complex control. Eur J Immunol 25:1249-1256
15. Naper C, Ryan JC, Nakamura MC, Lambracht D, Rolstad B, Vaage JT (1998) Identification of an inhibitory MHC receptor on alloreactive rat natural killer cells. J Immunol 160:219-224
16. c). Eur J Immunol 32:2031-2036
17. Naper C, Hayashi S, Kveberg L, Niemi EC, Lanier LL, Vaage JT, Ryan JC (2002b) Ly-49s3 is a promiscuous activating rat NK cell receptor for nonclassical MHC class I-encoded target ligands. J Immunol 169:22-30
18. Naper C, Hayashi S, Løvik G, Kveberg L, Niemi EC, Rolstad B, Dissen E, Ryan JC, Vaage JT (2002c) Characterization of a novel killer cell lectin-like receptor (KLRH1) expressed by alloreactive rat NK cells. J Immunol 168:5147-5154
19. Naper C, Dai K-Z, Kveberg L, Rolstad B, Niemi EC, Vaage JT, Ryan JC (2005) Two structurally related rat Ly49 receptors with opposing functions (Ly49 stimulatory receptor 5 and Ly49 inhibitory receptor 5) recognize nonclassical MHC class Ib-encoded target ligands. J Immunol 174:2702-2711
20. Naviaux RK, Costanzi E, Haas M, Verma IM (1996) The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses. J Virol 70:5701-5705
21. Nylenna Ø, Naper C, Vaage JT, Woon PY, Gauguier D, Dissen E, Ryan JC, Fossum S (2005) The genes and gene organization of the Ly49 region of the rat natural killer cell gene complex. Eur J Immunol 35:261-272
22. Onishi M, Kinoshita S, Morikawa Y, Shibuya A, Phillips J, Lanier LL, Gorman DM, Nolan GP, Miyajima A, Kitamura T (1996) Applications of retrovirus-mediated expression cloning. Exp Hematol 24:324-329
23. Osman MS, Silver ET, Varghese JC, Chang CS, Gong D-E, Audette GF, Hazes B, Kane KP (2005) Epitope mapping of Ly-49G and G-like receptors: CK-1 antibody defines a polymorphic site of functional interaction with class I ligand. J Leukoc Biol 77:644-651
24. Rolstad B, Ford WL (1983) The rapid elimination of allogeneic lymphocytes: relationship to established mechanisms of immunity and to lymphocyte traffic. Immunol Rev 73:87-113
25. Rolstad B, Fossum S (1987) Allogeneic lymphocyte cytotoxicity (ALC) in rats: establishment of an in vitro assay, and direct evidence that cells with natural killer (NK) activity are involved in ALC. Immunology 60:151-157
26. Ryan JC, Niemi EC, Nakamura MC (2000) Functional analysis of natural killer cell receptors in the RNK-16 rat leukemic cell line. Methods Mol Biol 121:283-295
27. Sanderson S, Shastri N (1994) LacZ inducible, antigen/MHC-specific T cell hybrids. Int Immunol 6:369-376
28. Smith HRC, Heusel JW, Mehta IK, Kim S, Dorner BG, Naidenko OV, Iizuka K, Furukawa H, Beckman DL, Pingel JT, Scalzo AA, Fremont DH, Yokoyama WM (2002) Recognition of a virus-encoded ligand by a natural killer cell activation receptor. Proc Natl Acad Sci USA 99:8826-8831
29. Vaage JT, Naper C, Løvik G, Lambracht D, Rehm A, Hedrich HJ, Wonigeit K, Rolstad B (1994) Control of rat natural killer cell-mediated allorecognition by a major histocompatibility complex region encoding nonclassical class I antigens. J Exp Med 180:641-651
30. Westgaard IH, Berg SF, Vaage JT, Wang LL, Yokoyama WM, Dissen E, Fossum S (2004) Rat NKp46 activates natural killer cell cytotoxicity and is associated with FcεRIγ and CD3ζ. J Leukoc Biol 76:1200-1206
31. Yokoyama WM, Plougastel BFM (2003) Immune functions encoded by the natural killer gene complex. Nat Rev Immunol 3:304-316