Unusual retention behaviour of 4-substituted piperidines on polybutadiene and polystyrene coated zirconia by comparison to reverse phase silica

Journal of Chromatography A

Volumn 1137, Issue 1, 2006, Pages 56-62

  Ovens, Caroline ^a   Sievwright, Dawn ^a   Silcock, Alan J ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

HPLC; Stationary phases; Zirconia

Indexed keywords

AROMATIC COMPOUNDS; PH EFFECTS; POLYSTYRENES; SILICA; SUBSTITUTION REACTIONS;

PIPERIDINE NITROGEN; POLYBUTADIENE (PBD); RETENTION PROPERTIES; STATIONARY PHASES;

ZIRCONIA;

1,3 BUTADIENE DERIVATIVE; CARBON; NITROGEN; PIPERIDINE DERIVATIVE; POLYBUTADIENE; POLYSTYRENE; SILICON DIOXIDE; UNCLASSIFIED DRUG; ZIRCONIUM OXIDE;

ARTICLE; CHEMICAL STRUCTURE; COMPARATIVE STUDY; ELUTION; MOLECULAR MECHANICS; PHARMACEUTICAL ENGINEERING; PRIORITY JOURNAL; REACTION ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE; STRUCTURE ANALYSIS; SUBSTITUTION REACTION;

BUFFERS; BUTADIENES; CHROMATOGRAPHY, LIQUID; ELASTOMERS; PIPERIDINES; POLYMERS; POLYSTYRENES; SILICON DIOXIDE; ZIRCONIUM;

EID: 33751366147     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2006.10.013     Document Type: Article

References (33)

1. Dong M.W., Miller G.D., and Paul R.K. J. Chromatogr. A 987 (2003) 283
2. Kirkland J.J., van Straten M.A., and Claessens H.A. J. Chromatogr. A 797 (1998) 111
3. Sunseri J.D., Cooper W.T., and Dorsey J.G. J. Chromatogr. A 1011 (2003) 23
4. Ramirez A., Lopez B.L., and Sierra L. J. Phys. Chem. B 107 (2003) 9275
5. Kobayashi A., Takezawa K., Takasaki H., Kanda T., and Kutsuna H. J. Chromatogr. A 1073 (2005) 163
6. Wyndham K.D., O'Gara J.E., Walter T.H., Glose K.H., Lawrence N.L., Alden B.A., Izzo G.S., Hudalla C.J., and Iraneta P.C. Anal. Chem. 75 (2003) 6781
7. Mistry K., and Grinberg N. J. Liq. Chromatogr. Relat. Technol. 28 (2005) 1055
8. Xiang Y., Yan B., Yue B., McNeff C.V., Carr P.W., and Lee M.L. J. Chromatogr. A 983 (2003) 83
9. Kawahara M., Nakamura H., and Nakajima T. J. Chromatogr. A 515 (1990) 149
10. Hu Y., Yang X., and Carr P.W. J. Chromatogr. A 968 (2002) 17
11. McNeff C., Zhao Q., and Carr P.W. J. Chromatogr. A 684 (1994) 201
12. Mcneff C., and Carr P.W. Anal. Chem. 67 (1995) 3886
13. Yang X.Q., Dai J., and Carr P.W. Anal. Chem. 75 (2003) 3153
14. Nawrocki J. J. Chromatogr. A 779 (1997) 29
15. Cox G.B., and Stout R.W. J. Chromatogr. A 384 (1987) 315
16. Nahum A., and Horvath C. J. Chromatogr. 203 (1981) 53
17. Cox G.B. J. Chromatogr. A 656 (1993) 353
18. Yang X., Dai J., and Carr P.W. J. Chromatogr. A 996 (2003) 13
19. Meyer V.R. Practical High-Performance Liquid Chromatography (2004), John Wiley & Sons Inc
20. Dai J., Yang X., and Carr P.W. J. Chromatogr. A 1005 (2003) 63
21. Nawrocki J., Dunlap C., Li J., Zhao J., McNeff C.V., McCormick A., and Carr P.W. J. Chromatogr. A 1028 (2004) 31
22. Nawrocki J., Dunlap C., McCormick A., and Carr P.W. J. Chromatogr. A 1028 (2004) 1
23. Zhao J.H., and Carr P.W. Anal. Chem. 71 (1999) 5217
24. Zhao J.H., and Carr P.W. Anal. Chem. 70 (1998) 3619
25. Li J.W., and Carr P.W. Anal. Chem. 68 (1996) 2857
26. Blackwell J.A., and Carr P.W. J. Liq. Chromatogr. 14 (1991) 2875
27. Nawrocki J., Rigney M., McCormick A., and Carr P.W. J. Chromatogr. A 657 (1993) 229
28. Li J., and Carr P.W. Anal. Chim. Acta 334 (1996) 239
29. Rigney M.P., Weber T.P., and Carr P.W. J. Chromatogr. A 484 (1989) 273
30. Zhao J.H., and Carr P.W. Anal. Chem. 72 (2000) 4413
31. Blackwell J.A., and Carr P.W. Anal. Chem. 64 (1992) 853
32. Emmert B., and Dorn W. Chem. Ber. 48 (1915) 687
33. Abdel M., Cynthia A.M., and Carson K.G. Tetrahedron Lett. 31 (1990) 5595