A multicenter clinical study of the safety and activity of maleimide-polyethylene glycol-modified hemoglobin (Hemospan®) in patients undergoing major orthopedic surgery

Anesthesiology

Volumn 105, Issue 6, 2006, Pages 1153-1163

  Olofsson, Christina ^a   Ahl, Torbjörn ^b   Johansson, Torsten ^c   Larsson, Sune ^d   Nellgård, Per ^e   Ponzer, Sari ^f   Fagrell, Bengt ^a   Przybelski, Robert ^g   Keipert, Peter ^h   Winslow, Nancy ^h   Winslow, Robert M ^h,i  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b DANDERYD HOSPITAL   (Sweden)

^c LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

^d UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^e SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^f KAROLINSKA INSTITUTE   (Sweden)

^g UNIVERSITY OF WISCONSIN MADISON   (United States)

^h SANGART INC   (United States)

ⁱ UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLASE; EPHEDRINE; HEMOGLOBIN DERIVATIVE; HEMOSPAN; LIVER ENZYME; MACROGOL; MALEIMIDE; RINGER ACETATE; TRIACYLGLYCEROL LIPASE;

ADULT; AGED; AMYLASE BLOOD LEVEL; ARTICLE; ASPIRATION; BLEEDING; BRADYCARDIA; CLINICAL PROTOCOL; CLINICAL TRIAL; CONNECTIVE TISSUE DISEASE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG SAFETY; DYSURIA; ELECTIVE SURGERY; ELECTROCARDIOGRAPHY MONITORING; FEMALE; FLUID BALANCE; GASTROINTESTINAL DISEASE; HEART VENTRICLE ARRHYTHMIA; HEMOGLOBIN DETERMINATION; HIP ARTHROPLASTY; HOLTER MONITORING; HUMAN; HYPERTENSION; HYPOTENSION; INFECTION; INFESTATION; INTOXICATION; LIVER FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; METABOLIC DISORDER; MULTICENTER STUDY; MUSCULOSKELETAL DISEASE; NEUROTOXICITY; ORTHOPEDIC SURGERY; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT DISEASE; SKIN DISEASE; SURGICAL PATIENT; TREATMENT OUTCOME; TRIACYLGLYCEROL LIPASE BLOOD LEVEL;

AGED; AGED, 80 AND OVER; ANESTHESIA, SPINAL; ARTHROPLASTY, REPLACEMENT, HIP; BLOOD LOSS, SURGICAL; BLOOD SUBSTITUTES; BLOOD TRANSFUSION; BODY WEIGHT; DOUBLE-BLIND METHOD; ELECTROCARDIOGRAPHY; ELECTROCARDIOGRAPHY, AMBULATORY; ENZYMES; FEMALE; HEMOGLOBINS; HUMANS; ISOTONIC SOLUTIONS; MALE; MALEIMIDES; MIDDLE AGED; ORTHOPEDIC PROCEDURES; POLYETHYLENE GLYCOLS; WATER-ELECTROLYTE BALANCE;

EID: 33751338255     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/00000542-200612000-00015     Document Type: Article

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