Increased serotonergic innervation of lumbosacral motoneurons of rolling mouse Nagoya in correlation with abnormal hindlimb extension

Journal of Veterinary Medicine Series C: Anatomia Histologia Embryologia

Volumn 35, Issue 6, 2006, Pages 387-392

  Koyanagi, Y ^a,b   Sawada, K ^a   Sakata Haga, H ^a   Jeong, Y G ^a,c   Fukui, Y ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b MUKOGAWA WOMEN'S UNIVERSITY   (Japan)

^c Konyang University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

HORSERADISH PEROXIDASE; SEROTONIN;

ANIMAL; ANIMAL DISEASE; ARTICLE; ATAXIA; BACK; FEMALE; GENETICS; HINDLIMB; IMMUNOHISTOCHEMISTRY; INNERVATION; MALE; METABOLISM; MOTONEURON; MOUSE; MOUSE MUTANT; PATHOPHYSIOLOGY; SKELETAL MUSCLE; SPINAL CORD;

ANIMALS; ATAXIA; FEMALE; HINDLIMB; HORSERADISH PEROXIDASE; IMMUNOHISTOCHEMISTRY; LUMBOSACRAL REGION; MALE; MICE; MICE, NEUROLOGIC MUTANTS; MOTOR NEURONS; MUSCLE, SKELETAL; SEROTONIN; SPINAL CORD;

ARMORACIA RUSTICANA; ATAXIA; TRITICUM AESTIVUM;

EID: 33751332732     PISSN: 03402096     EISSN: 14390264     Source Type: Journal    
DOI: 10.1111/j.1439-0264.2006.00697.x     Document Type: Article

References (20)

1. Alvarez, F. J., J. C. Pearson, D. Harrington, D. Dewey, L. Torbeck, and R. E. W. Fyffe, 1998: Distribution of 5-hydroxytryptamine-immunoreactive boutons on α-motoneurons in the lumbar spinal cord of adult cats. J. Comp. Neurol. 393, 69-83.
2. Bayliss, D. A., Y.-W. Li, and E. M. Talley, 1997: Effects of serotonin on caudal raphe neurons: inhibition of N- and P/Q-type calcium channels and the afterhyperpolarization. J. Neurophysiol. 77, 1362-1374.
3. Bose, P., and L.L. Vacca-Galloway, 1999: Increase in fiber density for immunoreactive serotonin, substance P, enkephalin and thyrotropin-releasing hormone occurs during the early presymptomic period of motoneuron disease in Wobbler mouse spinal cord ventral horn. Neurosci. Lett. 260, 196-200.
4. Campbell, D. B., and E. J. Hess, 1999: L-type calcium channels contribute to the tottering mouse dystonic episodes. Mol. Pharmacol. 55, 23-31.
5. 1A subunit throughout the mature rat brain and its relationship to neurotransmitter pathways. J. Comp. Neurol. 397, 251-267.
6. Doyle, J. L., and L. Stubbs, 1998: Ataxia, arrhythmia and ion-channel gene defects. Trends Genet. 14, 92-98.
7. Fletcher, C. F., C. M. Luts, T. N. O'Sullivan, J. D. Shaughnessy Jr., R. Hawkes, W. N. Frankel, N. G. Copeland, and N. A. Jenkins, 1996: Absence epilepsy in tottering mutant mice is associated with calcium channel defects. Cell 87, 607-617.
8. Green, M. C., and R. L. Sidman, 1962: Tottering - a neuromuscular mutation in the mouse. J. Hered. 53, 233-237.
9. Jeong, Y.-G., B. H. Hyun, and R. Hawkes, 2000: Abnormalities in cerebellar Purkinje cells in the novel ataxic mutant mouse, pogo. Dev. Brain Res. 125, 61-67.
10. Kiehn O., and T. Eken, 1998: Functional role of plateau potentials in vertebrate motor neurons. Curr. Opin. Neurobiol. 8, 746-752.
11. rol). J. Neurosci. 20, 5654-5662.
12. Oda, S., 1973: The observation of rolling mouse Nagoya (rol), a new neurological mutant, and its maintenance. Exp. Anim. 22, 281-286.
13. Oda, S., 1981: A new allele of the tottering locus, rolling mouse Nagoya, on chromosome no. 8 in the mouse. Jpn. J. Genet. 56, 295-299.
14. Okado, N., S. Homma, R. Ishihara, H. Sako, and K. Kohno, 1988: Differential innervation of specific motor neuron pools by serotoninergic fibers in the chick spinal cord. Neurosci. Lett. 94, 29-32.
15. 2+ channel gene CACNL1A4. Cell 87, 543-552.
16. 2 receptors promote plateau potentials in turtle spinal motoneurons by facilitating an L-type calcium current. J. Neurophysiol. 89, 954-959.
17. Rekling, J. C., G. D. Funk, D. A. Bayliss, X.-W. Dong, and J. L. Feldman, 2000: Synaptic control of motoneuronal excitability. Physiol. Rev. 80, 767-852.
18. 1A subunit immunoreactivity in deep cerebellar neurons of rolling mouse Nagoya. Neurosci. Lett. 316, 87-90.
19. Tanaka, H., S. Mori, and H. Kimura, 1992: Developmental changes in the serotoninergic innervation of hindlimb extensor motoneurons in neonatal rats. Dev. Brain Res. 65, 1-12.
20. Zwingman, T. A., P. E. Neumann, J. L. Noebels, and K. Herrup, 2001: Rocker is a new variant of the voltage-dependent calcium channel gene Cacna1a. J. Neurosci. 15, 1169-1178.