Attenuation of capillary leakage by hydroxyethyl starch (130/0.42) in a porcine model of septic shock

Critical Care Medicine

Volumn 34, Issue 12, 2006, Pages 3005-3010

  Marx, Gernot ^a   Pedder, Samantha ^b   Smith, Linda ^c   Swaraj, Seshapillai ^b   Grime, Steve ^c   Stockdale, Harold ^c   Leuwer, Martin ^b  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c ROYAL LIVERPOOL UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

Capillary leak syndrome; Fluid therapy; Hemodynamics; Hydroxyethyl starch; Sepsis; Shock; Starch

Indexed keywords

HETASTARCH;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; CAPILLARY LEAK SYNDROME; CENTRAL VENOUS PRESSURE; CONTROLLED STUDY; FEMALE; FLUID THERAPY; GENERALIZED EDEMA; HEMODYNAMICS; NONHUMAN; PERITONITIS; PLASMA VOLUME; PRIORITY JOURNAL; SEPTIC SHOCK; SWINE;

ANIMALS; CAPILLARY PERMEABILITY; DISEASE MODELS, ANIMAL; FEMALE; HETASTARCH; MOLECULAR WEIGHT; PLASMA SUBSTITUTES; PLASMA VOLUME; SHOCK, SEPTIC; SWINE;

EID: 33751316976     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000242755.74063.ED     Document Type: Article

References (44)

1. Martin GS, Mannino DM, Eaton S, et al: The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 2003; 348:1546-1554
2. Angus DC, Linde-Zwirble WT, Lidicker J, et al: Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001; 29:1303-1310
3. Marx G, Cobas Meyer M, Schuerholz T, et al: Hydroxyethyl starch and modified fluid gelatin maintain plasma volume in a porcine model of septic shock with capillary leakage. Intensive Care Med 2002; 28:629-635
4. Rivers E, Nguyen B, Havstad S, et al: Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001; 345:1368-1377
5. Marx G: Fluid therapy in sepsis with capillary leakage. Eur J Anaesthesiol 2003; 20:429-442
6. Webb AR, Tighe D, Moss RF, et al: Advantages of a narrow-range, medium molecular weight hydroxyethyl starch for volume maintenance in a porcine model of fecal peritonitis. Crit Care Med 1991; 19:409-416
7. Gallandat Huet RC, Siemons AW, Baus D, et al: A novel hydroxyethyl starch (Voluven) for effective perioperative plasma volume substitution in cardiac surgery. Can J Anaesth 2000; 47:1207-1215
8. Jungheinrich C, Scharpf R, Wargenau M, et al: The pharmacokinetics and tolerability of an intravenous infusion of the new hydroxyethyl starch 130/0.4 (6%, 500 mL) in mild-to-severe renal impairment. Anesth Analg 2002; 95:544-551
9. Langeron O, Doelberg M, Ang ET, et al: Voluven, a lower substituted novel hydroxyethyl starch (HES 130/0.4), causes fewer effects on coagulation in major orthopedic surgery than HES 200/0.5. Anesth Analg 2001; 92:855-862
10. Filep JG: Endogenous endothelin modulates blood pressure, plasma volume, and albumin escape after systemic nitric oxide blockade. Hypertension 1997; 30:22-28
11. Rencher AC: The contribution of individual variables to Hotelling's T2, Wilks' lambda, and R2. Biometrics 1993; 49:479-489
12. Einot I, Gabriel KR: A study of the powers of several methods of multiple comparisons. J Am Stat Assoc 1975; 70:574-583
13. Webb AR, Moss RF, Tighe D, et al: A narrow range, medium molecular weight pentastarch reduces structural organ damage in a hyperdynamic porcine model of sepsis. Intensive Care Med 1992; 18:348-355
14. Tighe D, Moss R, Heywood G, et al: Goal-directed therapy with dopexamine, dobutamine, and volume expansion: effects of systemic oxygen transport on hepatic ultrastructure in porcine sepsis. Crit Care Med 1995; 23:1997-2007
15. Schuerholz T, Sumpelmann R, Piepenbrock S, et al: Ringer's solution but not hydroxyethyl starch or modified fluid gelatin enhances platelet microvesicle formation in a porcine model of septic shock. Br J Anaesth 2004; 92:716-721
16. Diodato MD, Knoferl MW, Schwacha MG, et al: Gender differences in the inflammatory response and survival following haemorrhage and subsequent sepsis. Cytokine 2001; 14:162-169
17. Knoferl MW, Angele MK, Diodato MD, et al: Female sex hormones regulate macrophage function after trauma-hemorrhage and prevent increased death rate from subsequent sepsis. Ann Surg 2002; 235:105-112
18. Ernest D, Belzberg AS, Dodek PM: Distribution of normal saline and 5% albumin infusions in septic patients. Crit Care Med 1999; 27:46-50
19. Renkin EM, Tucker V, Rew K, et al: Plasma volume expansion with colloids increases blood-tissue albumin transport. Am J Physiol 1992; 262:H1054-1067
20. Farstad M, Heltne JK, Rynning SE, et al: Fluid extravasation during cardiopulmonary bypass in piglets-effects of hypothermia and different cooling protocols. Acta Anaesthesiol Scand 2003; 47:397-406
21. Marx G, Vangerow B, Burczyk C, et al: Evaluation of noninvasive determinants for capillary leakage syndrome in septic shock patients. Intensive Care Med 2000; 26:1252-1258
22. Sumpelmann R, Schurholz T, Marx G, et al: Haemodynamic, acid-base and electrolyte changes during plasma replacement with hydroxyethyl starch or crystalloid solution in young pigs. Paediatr Anaesth 2000; 10:173-179
23. Morisaki H, Bloos F, Keys J, et al: Compared with crystalloid, colloid therapy slows progression of extrapulmonary tissue injury in septic sheep. J Appl Physiol 1994; 77:1507-1518
24. Tighe D, Moss R, Hynd J, et al: Pretreatment with pentoxifylline improves the hemodynamic and histologic changes and decreases neutrophil adhesiveness in a pig fecal peritonitis model. Crit Care Med 1990; 18:184-189
25. Wollert S, Antonsson J, Gerdin B, et al: Intestinal mucosal injury during porcine faecal peritonitis. Eur J Surg 1995; 161:741-750
26. Traber DL: Microvascular leakage in sepsis. Crit Care Med 2000; 28:882-883
27. Linderkamp O, Holthausen H, Seifert J, et al: Accuracy of blood volume estimations in critically ill children using 125I-labelled albumin and 51Cr-labelled red cells. Eur J Pediatr 1977; 125:143-151
28. Swan H, Nelson AW: Blood volume measurement: concepts and technology. J Cardiovasc Surg (Torino) 1971; 12:389-401
29. Tumbleson ME: Swine in Biomedical Research. New York and London, Plenum Press, 1986
30. Deng X, Wang X, Andersson R: Endothelial barrier resistance in multiple organs after septic and nonseptic challenges in the rat. J Appl Physiol 1995; 78:2052-2061
31. Schuerholz T, Leuwer M, Cobas-Meyer M, et al: Terminal complement complex in septic shock with capillary leakage: Marker of complement activation? Eur J Anaesthesiol 2005; 22:541-547
32. Margarson MP, Soni N: Serum albumin: Touchstone or totem? Anaesthesia 1998; 53:789-803
33. Oz MC, FitzPatrick MF, Zikria BA, et al: Attenuation of microvascular permeability dysfunction in postischemic striated muscle by hydroxyethyl starch. Microvasc Res 1995; 50:71-79
34. Hoffmann JN, Vollmar B, Laschke MW, et al: Hydroxyethyl starch (130 kD), but not crystalloid volume support, improves microcirculation during normotensive endotoxemia. Anesthesiology 2002; 97:460-470
35. Collis RE, Collins PW, Gutteridge CN, et al: The effect of hydroxyethyl starch and other plasma volume substitutes on endothelial cell activation; an in vitro study. Intensive Care Med 1994; 20:37-41
36. Lv R, Zhou W, Zhang LD, et al: Effects of hydroxyethyl starch on hepatic production of cytokines and activation of transcription factors in lipopolysaccharide-administered rats. Acta Anaesthesiol Scand 2005; 49:635-642
37. Holbeck S, Bentzer P, Wikstrand C, et al: Dextran, gelatin, and hydroxyethyl starch do not affect permeability for albumin in cat skeletal muscle. Crit Care Med 2001; 29:123-128
38. Lehmann G, Boll M, Hilgers R, et al: HES 130 shows less alteration of pharmacokinetics than HES 200 when dosed repeatedly. Acta Anaesthesiol Scand 2005; 49:3-4
39. Dieterich HJ: Recent developments in European colloid solutions. J Trauma 2003; 54:S26-S30
40. Jungheinrich C, Sauermann W, Bepperling F, et al: Volume efficacy and reduced influence on measures of coagulation using hydroxyethyl starch 130/0.4 (6%) with an optimized in vivo molecular weight in orthopaedic surgery: A randomised, double-blind study. Drugs R D 2004; 5:1-9
41. Jungheinrich C, Neff TA: Pharmacokinetics of hydroxyethyl starch. Clin Pharmacokinet 2005; 44:681-699
42. Schmidt W, Schmidt H, Bauer H, et al: Influence of lidocaine on endotoxin-induced leukocyte-endothelial cell adhesion and macromolecular leakage in vivo. Anesthesiology 1997; 87:617-624
43. Lang JD Jr, Figueroa M, Chumley P, et al: Albumin and hydroxyethyl starch modulate oxidative inflammatory injury to vascular endothelium. Anesthesiology 2004; 100:51-58
44. Han X, Fink MP, Yang R, et al: Increased iNOS activity is essential for intestinal epithelial tight junction dysfunction in endotoxemic mice. Shock 2004; 21:261-270