Mechanism of cerebral fat embolism in subarachnoid hemorrhage: An experimental study

Neuropathology

Volumn 26, Issue 6, 2006, Pages 544-549

  Aydin, Mehmet D ^a,c   Kotan, Dilcan ^a   Aydin, Nazan ^a   Gundogdu, Cemal ^a   Onder, Arif ^b   Akcay, Fatih ^a  

^a ATATURK UNIVERSITY   (Turkey)

^b ONDOKUZ MAYIS UNIVERSITY   (Turkey)

^c ATATÜRK UNIVERSITY   (Turkey)

Author keywords

Fat embolism; Pulmonary edema; Subarachnoid hemorrhage

Indexed keywords

CHYLOMICRON; FAT; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN ARTERY; BRAIN EMBOLISM; CEREBRAL FAT EMBOLISM; CISTERNA MAGNA; EXPERIMENTAL STUDY; FAT EMBOLISM; GENERAL ANESTHESIA; HISTOPATHOLOGY; LIPOPROTEIN METABOLISM; LUNG; LUNG EDEMA; LUNG HEMORRHAGE; LUNG INJURY; MALE; NEUROGENIC PULMONARY EDEMA; NONHUMAN; PRIORITY JOURNAL; RABBIT; SUBARACHNOID HEMORRHAGE; SYSTEMIC CIRCULATION;

ANIMALS; ARACHNOID; BLOOD; CEREBRAL ARTERIES; EMBOLISM, FAT; ISOTONIC SOLUTIONS; MALE; PULMONARY EDEMA; RABBITS; SUBARACHNOID HEMORRHAGE;

EID: 33751301293     PISSN: 09196544     EISSN: 14401789     Source Type: Journal    
DOI: 10.1111/j.1440-1789.2006.00733.x     Document Type: Article

References (37)

1. Dragosavac D, Falcao AL, Araujo S, Terzi RG. Neurogenic pulmonary edema. Report of two cases. Arq Neuropsiquiatr 1997; 55: 305-308.
2. Bederson JB, Levy AL, Ding WH et al. Acute vasoconstriction after subarachnoid hemorrhage. Neurosurgery 1998; 42: 352-360.
3. Ames AD, Wright RL, Kowada M, Thurston JM, Majno G. Cerebral ischemia: II-The no-reflow phenomenon. Am J Pathol 1968; 52: 437-453.
4. Sehba FA, Mostafa G, Friedrich V Jr, Bederson JB. Related Acute microvascular platelet aggregation after subarachnoid hemorrhage. J Neurosurg 2005; 102: 1094-1100.
5. Di Giugno G, Rosa G. Neurogenic pulmonary edema during subarachnoid hemorrhage. Minerva Anesthesiol 1998; 64: 229-230.
6. Di Pasquale G, Andreoli A, Lusa AM et al. Cardiologic complications of subarachnoid hemorrhage. J Neurosurgery Sci 1998; 42: 33-36.
7. Rorbakken G, Brunvand H, Gundersen T, Farstad G. Cardiopulmonary complications in acute subarachnoid hemorrhage. Tidsskr Nor Laegeforen 1998; 118: 3430-3434.
8. Schwarz S, Schwab S, Keller E, Bertram M, Hacke W. Neurogenic disorders of heart and lung function in acute cerebral lesions. Nervenartz 1997; 68: 956-962.
9. Elmaraghi AW, Aksenow S, Byrick RJ, Richards RR, Schemitcsh EH. Pathophysiologic effect of fat embolism in a canine model of pulmonary contusion. J Bone Joint Surg Am 1999; 81: 1155-1164.
10. Fonte DA, Hausberger FX. Pulmonary free fatty acids in experimental fat embolism. J Trauma 1971; 11: 668-672.
11. Broderick JP, Brott TG, Duldner JE, Tomsick T, Leach A. Initial and recurrent bleeding are the major causes of death following subarachnoid hemorrhage. Stroke 1994; 25: 1342-1347.
12. Meixensberger J. Xenon 133-CBF measurements in severe head injury and subarachnoid haemorrhage. Acta Neurochir Supplement 1993; 59: 28-33.
13. Naveri L, Stromberg C, Saavedra JM. Angiotensin IV reverses the acute cerebral blood flow reduction after experimental subarachnoid hemorrhage in the rat. J Cereb Blood Flow Metab 1994; 14: 1096-1099.
14. Bederson JB, Guarino L, Germano IM. Failure of changes in cerebral perfusion pressure to account for ischemia caused by subarachnoid hemorrhage: a new experimental model. Soc Neurosci Abstr 1994; 20: 224.
15. Weaver J, Fisher M. Subarachnoid hemorrhage. An update of pathogenesis, diagnosis and management. J Neurol Sci 1994; 125: 119-131.
16. Bederson JB, Germano IM, Guarino L. Cortical blood flow and cerebral perfusion ressure in a new noncraniotomy model of subarachnoid hemorrhage in the rat. Stroke 1995; 26: 1086-1091.
17. Jakobsen M. Role of initial brain ischemia in subarachnoid hemorrhage following aneurysm rupture: a pathophysiological survey. Acta Neurol Scand Suppl 1992; 141: 1-33.
18. Adams HPJ, Kassell NF, Torner JC. Early management of subarachnoid hemorrhage: a report of the Cooperative Aneurysm Study. J Neurosurg 1981; 46: 454-466.
19. Weir BK. Pulmohary edema following fatal aneurysm rupture. J Neurosurg 1978; 49: 502-507.
20. Wohns RNW, Tamas L, Pierce KR, Howe JF. Chlorpromazine treatment for neurogenic pulmonary edema. Crit Care Med 1985; 13: 210-215.
21. Hijdra A, Vermeulen M, Van Gijn J, Van Crevel H. Respiratory arrest in subarachnoid hemorrhage. Neurology 1984; 34: 1501-1503.
22. Garcia-uria J, Hoff JT, Miranda S, Nishimura M. Experimental neurogenic pulmonary edema. Part 2: the role of cardiopulmonary pressure change. J Neurosurg 1981; 54: 632-636.
23. Lagerkranser M, Pehrsson K, Sylve'n C. Neurogenic pulmonary edema. A review of the pathophysiology with cliniical and therapotic implications. Acta Med Scand 1982; 212: 267-271.
24. Millen JE, Glauser FL. Low levels of concussive brain trauma and pulmonary edema. J Appl Physiol Resp Environ 1983; 53: 666-670.
25. Simon RP, Bayne LL. Pulmonary lymphatic flow alterations during intracranial hypertension in sheep. Ann Neurol 1984; 15: 188-194.
26. Mayer SA, Fink ME, Homma S et al. Cardiac injury associated with neurogenic pulmonary edema following subarachnoid hemorrhage. Neurology 1994; 44: 815-820.
27. Watanabe T, Sekiguchi K, Inoue A, Taniguchi Y, Sato S. Clinical evaluation of neurogenic pulmonary edema following acute stage of subarachnoid hemorrhage. No Shinkei Geka 1992; 20: 417-422.
28. Aydin MD, Akcay F, Aydin N, Gundogdu C. Cerebral fat embolism: pulmonary contussion is a more important etiology than long bone fractures. Clin Neuropathol 2005; 24: 86-90.
29. Bracco D, Favre JB, Joris R, Ravussin A. Fatal fat embolism syndrome: A case report. J Neurosurg Anesthesiol 2000; 12: 221-224.
30. Kim HJ, Lee CH, Lee SH, Moon TY. Magnetic resonance imaging and histologic findings of experimental cerebral fat embolism. Invest Radiol 2003; 38: 625-634.
31. Bardana D, Rudan J, Cervenko F, Smith R. Fat embolism syndrome in a patient demonstrating only neurologic symptoms. Can J Surg 1998; 41: 398-402.
32. Takahashi M, Suzuki R, Osakabe Y et al. Magnetic resonance imaging findings in cerebral fat embolism: correlation with clinical manifestations. J Trauma 1999; 46: 324-327.
33. Schievink WI, Wijdicks EF, Parisi JE. Sudden death from aneurysmal subarachnoid hemorrhage. Neurology 1995; 45: 871-874.
34. Walder B, Bründler MA, Tötsch M, Elia N, Morel DR. Influence of the type and rate of subarachnoid fluid infusion on lethal neurogenic pulmonary edema in rats. J Neurosurg Anesthesiol 2002; 14: 194-203.
35. Barie PS, Minnear FL, Malik AB. Increased pulmonary capillary permeability after bone marrow injection in sheep. Am Rew Respir Dis 1981; 123: 648-653.
36. Hideki S, Kaoru K, Minako O, Kazunori A, Seiji O. Cerebral Fat embolism studied by magnetic resonance imaging, transcranial doppler sonography, and single photon emission computed tomography. Case Report. J Trauma 1997; 43: 345-348.
37. Kamenar E, Burger P. Cerebral fat embolism: a neuropathological study of microembolic state. Stroke 1980; 11: 477-481.