PH: Effects on growth and productivity of cell lines producing monoclonal antibodies: Control in large-scale fermenters

New Genetics and Society

Volumn 17, Issue 2-3, 1997, Pages 125-132

  Wayte, J ^a   Boraston, R ^a   Bland, H ^a   Varley, J ^a   Brown, M ^b  

^a LONZA Biologies Pic   (United Kingdom)

^b UNIVERSITY OF READING   (United Kingdom)

Author keywords

Cell culture; Growth; pH; Productivity

Indexed keywords

EID: 33751292424     PISSN: 14636778     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

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4. Brown, M.E., Boraston, R.C., Wayte, J.R.T. et al. (1996) The effect of pH on growth and productivity of cell lines producing monoclonal antibodies at large scale. In Cell Culture Engineering V, San Diego, February.
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7. Nienow, A.W., Langheinrich, C., Stevenson, N.C. et al. (1996) Homogenisation and oxygen transfer rates in large agitated and sparged animal cell bioreactors: some implications for growth and production. Gytotechnology, 22, 87-94.
8. Rossler, B., Lubben, H. & Kretzmer, G. (1996) Temperature-a simple parameter for process optimization in fed-batch cultures of recombinant Chinese hamster cvary cells. Enyme and Microbial Technology, 18, 423-427.
9. Wang, J., Honda, H., Watanabe, H. et al. (1995) Enhancement of TPA production under hyperoxic conditions by BHK cells in serum-free and serum-containing cultures. Journal of Fermentation and Bioengineering, 79, 579-584.