Cardiovascular effects of Nemopilema nomurai (Scyphozoa: Rhizostomeae) jellyfish venom in rats

Toxicology Letters

Volumn 167, Issue 3, 2006, Pages 205-211

  Kim, Euikyung ^a   Lee, Seunghwan ^a   Kim, Jong Shu ^a   Yoon, Won Duk ^b   Lim, Donghyun ^b   Hart, Andrew J ^c   Hodgson, Wayne C ^c  

^a Gyeongsang National University   (South Korea)

^b National Fisheries Research and Development Institute (NFRDI)   (South Korea)

^c MONASH UNIVERSITY   (Australia)

Author keywords

Anaesthetized rat; Cardiovascular; In vivo; Nematocyst venom; Nemopilema nomurai; Rhizostomeae

Indexed keywords

CALCIUM CHANNEL STIMULATING AGENT; COELENTERATE VENOM; FELODIPINE; PRAZOSIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE FLUCTUATION; BRADYCARDIA; CARDIOTOXICITY; CARDIOVASCULAR EFFECT; CHRONOTROPISM; CONTROLLED STUDY; DOSE CALCULATION; DOSE RESPONSE; ENVENOMATION; HEART MUSCLE CONTRACTILE FORCE; HEART MUSCLE CONTRACTILITY; HYPOTENSION; INOTROPISM; JELLYFISH; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TOXICITY TESTING; VASCULAR RING;

ANIMALS; BLOOD PRESSURE; CNIDARIAN VENOMS; HEART RATE; MALE; MYOCARDIAL CONTRACTION; PULSE; RATS; RATS, SPRAGUE-DAWLEY; SCYPHOZOA; VASOCONSTRICTION;

NEMOPILEMA NOMURAI; RHIZOSTOMEAE; SCYPHOZOA;

EID: 33751280132     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2006.09.009     Document Type: Article

References (26)

1. Bailey P.M., Little M., Jelinek G.A., and Wilce J.A. Jellyfish envenoming syndromes: unknown toxic mechanisms and unproven therapies. Med. J. Aust. 178 (2003) 34-37
2. Bloom D.A., Burnett J.W., and Alderslade P. Partial purification of box jellyfish (Chironex fleckeri) nematocyst venom isolated at the beachside. Toxicon 36 (1998) 1075-1085
3. Carrette T., and Seymour J. A rapid and repeatable method for venom extraction from cubozoan nematocysts. Toxicon 44 (2004) 135-139
4. Edwards L., and Hessinger D.A. Portuguese man-of-war (Physalia physalis) venom induces calcium influx into cells by permeabilizing plasma membranes. Toxicon 38 (2000) 1015-1028
5. Fenner P.J., Williamson J.A., Burnett J.W., Colquhoun D.M., Godfrey S., Gunawardane K., and Murtha W. The "Irukandji syndrome" and acute pulmonary oedema. Med. J. Aust. 149 (1988) 150-156
6. Fenner P.J., and Williamson J.A. Worldwide deaths and severe envenomation from jellyfish stings. Med. J. Aust. 165 (1996) 658-661
7. Gershwin L. Comments on Chiropsalmus (Cnidaria: Cubozoa: Chirodropida): a preliminary revision of the Chiropsalmidae, with descriptions of two new genera and two new species. Zootaxa 1231 (2006) 1-42
8. Huynh T.T., Seymour J., Pereira P., Mulcahy R., Cullen P., Carrette T., and Little M. Severity of Irukandji syndrome and nematocyst identification from skin scrapings. Med. J. Aust. 178 (2003) 38-41
9. Kawahara M., Uye S.-I., Ohtsu K., and Lizumi H. Unusual population explosion of the giant jellyfish Nemopilema nomurai (Scyphozoa: Rhizostomeae) in East Asian waters. Mar. Ecol.-Prog. Ser. 307 (2006) 161-173
10. Kishinouye K. Echizen kurage. Doubutsugaku zasshi 34 (1922) 343-346 (in Japanese)
11. Kramp P.L. Synopsis of the medusae of the world. J. Mar. Biol. Assoc. UK 40 (1961) 1-469
12. Little M., Mulcahy R.F., and Wenck D.J. Life-threatening cardiac failure in a healthy young female with Irukandji syndrome. Anaesth. Intensive Care 29 (2001) 178-180
13. Mingliang Z., and Qin Shede. The marine stinger in South China Sea. Chin. J. Mar. Drugs 4 (1991) 36
14. Noguchi K., Sakanashi M., Matsuzaki T., Nakasone J., Sakanashi M., Koyama T., Hamadate N., and Sakanashi M. Cardiovascular effects and lethality of venom from nematocysts of the box-jellyfish Chiropsalmus quadrigatus (Habu-kurage) in anaesthetized rats. Toxicon 45 (2005) 519-526
15. Nomura J.T., Sato R.L., Ahern R.M., Snow J.L., Kuwaye T.T., and Yamamoto L.G. A randomized paired comparison trial of cutaneous treatments for acute jellyfish (Carybdea alata) stings. Am. J. Emerg. Med. 20 (2002) 624-626
16. Omori M., and Kitamura M. Taxonomic review of three Japanese species of edible jellyfish (Scyphozoa: Rhizostomeae). Plankton Biol. Ecol. 51 (2004) 36-51
17. Omori M., and Nakano E. Jellyfish fisheries in southeast Asia. Hydrobiologia 451 (2001) 19-26
18. O'Reilly G.M., Isbister G.K., Lawrie P.M., Treston G.T., and Currie B.J. Prospective study of jellyfish stings from tropical Australia, including the major box jellyfish Chironex fleckeri. Med. J. Aust. 175 (2001) 652-655
19. Ramasamy S., Isbister G.K., Seymour J.E., and Hodgson W.C. The in vivo cardiovascular effects of an Australasian box jellyfish (Chiropsalmus sp.) venom in rats. Toxicon 45 (2005) 321-327
20. Ramasamy S., Isbister G.K., Seymour J.E., and Hodgson W.C. The in vivo cardiovascular effects of the Irukandji jellyfish (Carukia barnesi) nematocyst venom and a tentacle extract in rats. Toxicol. Lett. 155 (2005) 135-141
21. Ramasamy S., Isbister G.K., Seymour J.E., and Hodgson W.C. Pharmacologically distinct cardiovascular effects of box jellyfish (Chironex fleckeri) venom and a tentacle-only extract in rats. Toxicol. Lett. 155 (2005) 219-226
22. Silfen R., Vilan A., Wohl I., and Leviav A. Mediterranean jellyfish (Rhopilema nomadica) sting. Burns 29 (2003) 868-870
23. Tibballs J., Hawdon G., and Winkel K. Mechanism of cardiac failure in Irukandji syndrome and first aid treatment for stings. Anaesth. Intensive Care 29 (2001) 552
24. Uchida T. Distribution of scyphomedusae in Japanese and adjacent waters. J. Fac. Sci. Hokkaido Univ. 12 (1954) 209-219
25. Watters M.R., and Stommel E.W. Marine neurotoxins: envenomations and contact toxins. Curr. Treat Options Neurol. 6 (2004) 115-123
26. Watters M.R. Tropical marine neurotoxins: venoms to drugs. Semin. Neurol. 25 (2005) 278-289