Chemical coding of myenteric neurons with different axonal projection patterns in the porcine ileum

Journal of Anatomy

Volumn 209, Issue 6, 2006, Pages 733-743

  Jungbauer, Carsten ^a   Lindig, Tobias M ^a   Schrödl, Falk ^a   Neuhuber, Winfried ^a   Brehmer, Axel ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Chemical coding; Enteric nervous system; Gut; Innervation; Neuron type

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; GALANIN; LEUCINE ENKEPHALIN; NEURONAL NITRIC OXIDE SYNTHASE; PROTEIN ANTIBODY; SUBSTANCE P; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANIMAL TISSUE; ANUS; ARTICLE; CELL STRUCTURE; CELL SUBPOPULATION; CELL TYPE; CHEMICAL ANALYSIS; CONTROLLED STUDY; DENDRITE; FEMALE; ILEUM; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INNERVATION; INTESTINE MUSCLE; MALE; MOTONEURON; MOUTH; MYENTERIC PLEXUS; NERVE CELL; NERVE ENDING; NERVE FIBER; NERVE PROJECTION; NEUROFILAMENT; NONHUMAN; PRIORITY JOURNAL; SWINE;

ANIMALS; AXONS; CALCITONIN GENE-RELATED PEPTIDE; DENDRITES; ENKEPHALIN, LEUCINE; GALANIN; ILEUM; IMMUNOHISTOCHEMISTRY; MYENTERIC PLEXUS; NEUROFILAMENT PROTEINS; NEURONS; SWINE; VASOACTIVE INTESTINAL PEPTIDE;

SUIDAE; SUS SCROFA;

EID: 33751279496     PISSN: 00218782     EISSN: 14697580     Source Type: Journal    
DOI: 10.1111/j.1469-7580.2006.00653.x     Document Type: Article

References (40)

1. Anselmi L, Stella SL Jr, Lakhter A, Hirano A, Tonini M, Sternini C (2005) Galanin receptors in the rat gastrointestinal tract. Neuropeptides 39, 349-352.
2. Bishop AE, Polak JM, Bauer FE, Christofides ND, Carlei F, Bloom SR (1986) Occurrence and distribution of a newly discovered peptide, galanin, in the mammalian enteric nervous system. Gut 27, 849-857.
3. Brehmer A, Stach W (1997) Morphological classification of NADPHd-positive and - negative myenteric neurons in the porcine small intestine. Cell Tissue Res 287, 127-134.
4. Brehmer A, Stach W, Krammer H-J, Neuhuber W (1998) Distribution, morphology and projections of nitrergic and non-nitrergic submucosal neurons in the pig small intestine. Histochem Cell Biol 109, 87-94.
5. Brehmer A, Schrödl F, Neuhuber W (1999) Morphological classifications of enteric neurons - 100 years after Dogiel. Anat Embryol 200, 125-135.
6. Brehmer A, Schrödl F, Neuhuber W (2002a) Morphological phenotyping of enteric neurons using neurofilament immunohistochemistry renders chemical phenotyping more precise in porcine ileum. Histochem Cell Biol 117, 257-263.
7. Brehmer A, Schrödl F, Neuhuber W (2002b) Correlated morphological and chemical phenotyping in myenteric type V neurons of porcine ileum. J Comp Neurol 453, 1-9.
8. Brehmer A, Croner R, Dimmler A, Papadopoulos T, Schrödl F, Neuhuber W (2004a) Immunohistochemical characterization of putative primary afferent (sensory) myenteric neurons in human small intestine. Auton Neurosci 112, 49-59.
9. Brehmer A, Schrödl F, Neuhuber W, Tooyama I, Kimura H (2004b) Co-expression pattern of neuronal nitric oxide synthase and two variants of choline acetyltransferase in myenteric neurons of porcine ileum. J Chem Neuroanat 27, 33-41.
10. Brehmer A, Lindig TM, Schrödl F, et al. (2005) Morphology of enkephalin-immunoreactive myenteric neurons in the human gut. Histochem Cell Biol 123, 131-138.
11. Brookes SJH (2001) Retrograde tracing of enteric neuronal pathways. Neurogastroenterol Motil 13, 1-18.
12. Brown DR, Hildebrand KR, Parsons AM, Soldani G (1990) Effects of galanin on smooth muscle and mucosa of porcine jejunum. Peptides 11, 497-500.
13. Brown DR, Timmermans J-P (2004) Lessons from the porcine enteric nervous system. Neurogastroenterol Motil 16(Suppl. 1), 50-54.
14. Costa M, Brookes SJH, Steele PA, Gibbins I, Burcher E, Kandiah CJ (1996) Neurochemical classification of myenteric neurons in the guinea-pig ileum. Neuroscience 75, 949-967.
15. Dogiel AS (1899) Ueber den Bau der Ganglien in den Geflechten des Darmes und der Gallenblase des Menschen und der Säugethiere. Arch Anat Physiol Anat Abt (Leipzig), 130-158.
16. Furness JB, Robbins HL, Xiao J, Stebbing MJ, Nurgali K (2004) Projections and chemistry of Dogiel type II neurons in the mouse colon. Cell Tissue Res 317, 1-12.
17. Furness JB (2006) The Enteric Nervous System. Oxford: Blackwell.
18. Grider JR (1993) Interplay of VIP and nitric oxide in regulation of the descending relaxation phase of peristalsis. Am J Physiol 264, G334-G340.
19. Hens J, Schrödl F, Brehmer A, et al. (2000) Mucosal projections of enteric neurons in the porcine small intestine. J Comp Neurol 421, 429-436.
20. Hens J, Gajda M, Scheuermann DW, Adriaensen D, Timmermans J-P (2002) The longitudinal smooth muscle layer of the pig small intestine is innervated by both myenteric and submucous neurons. Histochem Cell Biol 117, 481-492.
21. Mann PT, Southwell BR, Ding YQ, Shigemoto R, Mizuno N, Furness JB (1997) Localisation of neurokinin 3 (NK3) receptor immunoreactivity in the rat gastrointestinal tract. Cell Tissue Res 289, 1-9.
22. Mann PT, Furness JB, Southwell BR (1999) Choline acetyltransferase immunoreactivity of putative intrinsic primary afferent neurons in the rat ileum. Cell Tissue Res 297, 241-248.
23. Nurgali K, Stebbing MJ, Furness JB (2004) Correlation of electrophysiological and morphological characteristics of enteric neurons in the mouse colon. J Comp Neurol 468, 112-124.
24. Porcher C, Jule Y, Henry M (2000) A qualitative and quantitative study on the enkephalinergic innervation of the pig gastrointestinal tract. J Histochem Cytochem 48, 333-343.
25. Porter AJ, Wattchow DA, Brookes SJH, Costa M (2002) Cholinergic and nitrergic interneurones in the myenteric plexus of the human colon. Gut 51, 70-75.
26. Sang Q, Williamson S, Young HM (1997) Projections of chemically identified myenteric neurons of the small and large intestine of the mouse. J Anat 190, 209-222.
27. Scheuermann DW, Stach W, De Groodt-Lasseel MHA, Timmermans J-P (1987) Calcitonin gene-related peptide in morphologically well-defined type II neurons of the enteric nervous system in the porcine small intestine. Acta Anat 129, 325-328.
28. Scheuermann DW, Krammer H-J, Timmermans J-P, Stach W, Adriaensen D, De Groodt-Lasseel MHA (1991a) Fine structure of morphologically well-defined type Ii neurons in the enteric nervous system of the porcine small intestine revealed by immunoreactivity for calcitonin gene-related peptide. Acta Anat 142, 236-241.
29. Scheuermann DW, Stach W, Timmermans J-P (1991b) Functional morphology of the enteric nervous system. Verh Anat Ges 85, 75-85.
30. Scheuermann DW, Stach W, Timmermans J-P, et al. (1991c) Immunohistochemical visualization of the nervous system in the porcine small intestine using antisera against the cytoskeletal proteins MAP1 and MAP2, in combination with neuropeptide immunocytochemistry. Eur J Morph 29, 219-231.
31. Schmidt P, Rasmussen TN, Holst JJ (1993) Release of immunoreactive somatostatin, vasoactive intestinal polypeptide (VIP), and galanin during propulsive complexes in isolated pig ileum. Peptides 14, 215-220.
32. Stach W (1980) Zur neuronalen Organisation des Plexus myentericus (Auerbach) im Schweinedünndarm. I. Typ I-Neurone. Z Mikrosk Anat Forsch 94, 833-849.
33. Stach W (1989) A revised morphological classification of neurons in the enteric nervous system. In: Singer, MV, Goebell, H, eds. Nerves and the Gastrointestinal Tract. Lancaster: Kluwer, pp. 29-45.
34. Sundler F, Ekblad E, Hakanson R (1993) Localization and colocalization of gastrointestinal peptides. In Gastrointestinal Regulatory Peptides (ed. Brown DR), pp. 1-28. Berlin: Springer-Verlag.
35. Timmermans J-P, Barbiers M, Scheuermann DW, et al. (1994) Distribution pattern, neurochemical features and projections of nitrergic neurons in the pig small intestine. Ann Anat 176, 515-525.
36. Timmermans J-P, Adriaensen D, Cornelissen W, Scheuermann DW (1997) Structural organization and neuropeptide distribution in the mammalian enteric nervous system, with special attention to those components involved in mucosal reflexes. Comp Biochem Physiol 118A, 331-340.
37. Timmermans J-P, Hens J, Adriaensen D (2001) Outer submucous plexus: An intrinsic nerve network involved in both secretory and motility processes in the intestine of mammals and humans. Anat Rec 262, 71-78.
38. Tooyama I, Kimura H (2000) A protein encoded by an alternative splice variant of choline acetyltransferase mRNA is localized preferentially in peripheral nerve cells and fibres. J Chem Neuroanat 17, 217-226.
39. Van Ginneken C, Van Meir F, Sommereyns G, Sys S, Weyns A (1998) Nitric oxide synthase expression in enteric neurons during development in the pig duodenum. Anat Embryol 198, 399-408.
40. Wattchow DA, Porter AJ, Brookes SJH, Costa M (1997) The polarity of neurochemically defined myenteric neurons in the human colon. Gastroenterology 113, 497-506.