Age-dependent augmentation of cardiac endothelial NOS in a genetic rat model of heart failure

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 273, Issue 3 42-3, 1997, Pages

  Khadour, Fadi H ^a   Kao, Ruey H ^b   Park, Sonhee ^b   Armstrong, Paul W ^a   Holycross, Bethany J ^b   Schulz, Richard ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Hypertension; Nitrate nitrite; Ventricular hypertrophy

Indexed keywords

CALCIUM ION; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ADOLESCENT; AGED; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC SUSCEPTIBILITY; HEART FAILURE; HEART LEFT VENTRICLE MASS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC BLOOD PRESSURE; VASCULAR ENDOTHELIUM;

EID: 33751268451     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1997.273.3.h1223     Document Type: Article

References (15)

1. Amezcua, J. L., R. M. J. Palmer, B. M. Souza, and S. Moncada. Nitric oxide synthesized from L-arginine regulates vascular tone in the coronary circulation of the rabbit. Br. J. Pharmacol. 97: 1119-1124, 1989.
2. Balligand, J.-L., R. A. Kelly, P. A. Marsden, T. W. Smith, and T. Michel. Control of cardiac muscle cell function by an endogenous nitric oxide signaling system. Proc. Natl. Acad. Sci. USA 90: 347-351, 1993.
3. Balligand, J.-L., L. Kobzik, X. Han, D. M. Kaye, L. Belhassen, D. S. O'Hara, R. A. Kelly, T. W. Smith, and T. Michel. Nitric oxide-dependent parasympathetic signaling is due to activation of constitutive endothelial (type III) nitric oxide synthase in cardiac myocytes. J. Biol. Chem. 270: 14582-14586, 1995.
4. Balligand, J.-L., D. Ungureanu-Longrois, R. A. Kelly, L. Kobzik, D. Pimental, T. Michel, and T. W. Smith. Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium. J. Clin. Invest. 91: 2314-2319, 1993.
5. Brady,A. J., J. B. Warren, P. A. Poole-Wilson, T. J. Williams, and S. E. Harding. Nitric oxide attenuates cardiac myocyte contraction. Am. J. Physiol. 265 (Heart Circ. Physiol. 34): H176-H182, 1993.
6. DeBelder, A. J., M. W. Radomski, H. J. Why, P. J. Richardson, C. A. Bucknall, E. Salas, J. F. Martin, and S. Moncada. Nitric oxide synthase activities in human myocardium. Lancet 341: 84-85, 1993.
7. Gerdes, A. M., T. Onodera, X. Wang, and S. A. McCune. Myocyte remodeling during the progression to failure in rats with hypertension. Hypertension 28: 609-614, 1996.
8. Giorgio, O., R. Abbi, F. Quaini, J. Kajstura, W. Cheng, J. A. Nitahara, E. Quaini, C. Di Loreto, C. A. Beltrami, S. Krajewski, J. C. Reed, and P. Anversa. Programmed cell death affects the failing human heart (Abstract). Circulation 94: 1-157, 1996.
9. 15N]nitrate in biological fluids. Anal. Biochem. 126: 131-138, 1982.
10. Haas, G. J., S. A. McCune, D. M. Brown, and R. J. Cody. Echocardiographic characterization of left ventricular adaptation in a genetically determined heart failure rat model. Am. Heart J. 130: 806-811, 1995.
11. Habib, F. M., D. R. Spingall, G. J. Davies, C. M. Oakley, M. H. Yacoub, and J. M. Polak. Tumor necrosis factor and inducible nitric oxide synthase in dilated cardiomyopathy. Lancet 347: 1151-1155, 1996.
12. Han, X., Y. Shimoni, and W. R. Giles. A cellular mechanism for nitric oxide-mediated cholinergic control of mammalian heart rate. J. Gen. Physiol. 106: 45-65, 1995.
13. Haywood, G. A., P. S. Tsao, H. Von der Leyen, M. J. Mann, P. J. Keeling, P. T. Trindade, N. P. Lewis, C. D. Byrne, P. R. Rickenbacher, N. H. Bishopric, J. P. Cooke, W. J. McKenna, and M. B. Fowler. Expression of inducible nitric oxide synthase in human heart failure. Circulation 93: 1087-1094, 1996.
14. cp) rats. Am. J. Physiol. 273 (Heart Circ. Physiol. 42): H228-H233, 1997.
15. Keim, M., and J. Schrader. Control of coronary vascular tone by nitric oxide. Circ. Res. 66: 1561-1575, 1990.