Ryanodine and left ventricular function in intact dogs: Dissociation of force-based and velocity-based indexes

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 273, Issue 3 42-3, 1997, Pages

  Prabhu, Sumanth D ^a   Rozek, M Marius ^a   Murray, David R ^a   Freeman, Gregory L ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Calcium handling; Cardiac mechanics; Ventricular contraction; Ventricular relaxation

Indexed keywords

CALCIUM ION; RYANODINE;

ANIMAL EXPERIMENT; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DOG; FEMALE; HEART LEFT VENTRICLE CONTRACTION; HEART LEFT VENTRICLE DP-DT; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE PRESSURE; HEART RATE; HEART VENTRICLE ENDDIASTOLIC PRESSURE; HEART WORK; HEMODYNAMICS; MALE; NONHUMAN; PRIORITY JOURNAL; SARCOPLASMIC RETICULUM;

EID: 33751261872     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1997.273.3.h1561     Document Type: Article

References (15)

1. Akera, T. Pharmacological agents and myocardial calcium. In: Calcium and the Heart, edited by G. A. Langer. New York: Raven, 1990, p. 325-327.
2. Bailey, B. A., and S. R. Houser. Sarcoplasmic reticulum-related changes in cytosolic calcium in pressure-overload-induced feline LV hypertrophy. Am. J. Physiol. 265 (Heart Cire. Physiol. 34): H2009-H2016, 1993.
3. 2+ is buffered. Circ. Res. 68: 897-902, 1991.
4. 2+ release in cardiac muscle activation during postrest recovery. Am. J. Physiol. 248 (Heart Circ. Physiol. 17): H366-H381, 1985.
5. Capasso, J. M., J. E. Strobeck, and E. H. Sonnenblick. Myocardial mechanical alterations during gradual onset long-term hypertension in rats. Am. J. Physiol. 241 (Heart Circ. Physiol. 10): H435-H441, 1981.
6. Fabiato, A. Effects of ryanodine in skinned cardiac cells. Federation Proc. 44: 2970-2976, 1985.
7. Feher, J. J., and G. B. Lipford. Mechanism of action of ryanodine on cardiac sarcoplasmic reticulum. Biochim. Biophys. Acta 813: 77-86, 1985.
8. 2+ during inotropic interventions in isolated rat myocytes. J. Physiol. (Lond.) 437: 351-375, 1991.
9. Freeman, G. L., and J. T. Colston. Evaluation of long-term variance of left ventricular performance indexes in closed-chest dogs. Am. J. Physiol. 257 (Heart Circ. Physiol. 26): H70-H78, 1989.
10. Glower, D. D., J. A. Spratt, N. D. Snow, J. S. Kabas, J. W. Davis, C. O. Olsen, G. S. Tyson, D. C. Sabiston, and J. S. Rankin. Linearity of the Frank-Starling relationship in the intact heart: the concept of preload recruitable stroke work. Circulation 71: 994-1009, 1985.
11. 2+. Circulation 82: 1266-1278, 1990.
12. Hartley, H. O. The modified Gauss-Newton method for the fitting of non-linear regression functions by least squares. Technometrics 3: 269-280, 1961.
13. Hoit, B. D., Y. Shao, M. Gabel, and R. A. Walsh. Disparate effects of early pressure overload hypertrophy on velocity-dependent and force-dependent indices of ventricular performance in the conscious baboon. Circulation 91: 1213-1220, 1995.
14. Inui, M., S. Wang, A. Saito, and S. Fleischer. Characterization of junctional and longitudinal sarcoplasmic reticulum from heart muscle. J. Biol. Chem. 263: 10843-10850, 1988.
15. Jenden, D. J., and A. S. Fairhurst. The pharmacology of ryanodine. Pharmacol. Rev. 21: 1-25, 1969.