DNA immunization with 2C FMDV non-structural protein reveals the presence of an immunodominant CD8+, CTL epitope for Balb/c mice

Antiviral Research

Volumn 72, Issue 3, 2006, Pages 178-189

  Barfoed, Annette Malene ^a   Rodriguez, Fernando ^b   Therrien, Dominic ^c   Borrego, Belen ^d   Sobrino, Francisco ^d,e   Kamstrup, Søren ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b CENTRE DE RECERCA EN SANITAT ANIMAL CRESA   (Spain)

^c STATENS SERUM INSTITUT   (Denmark)

^d Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria   (Spain)

^e CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

Author keywords

CTL epitope; DNA vaccination; Flow cytometry; Foot and mouth disease virus; Intracellular cytokine staining; Non structural proteins

Indexed keywords

AMINO ACID; DNA VACCINE; EPITOPE; GAMMA INTERFERON; HERMES ANTIGEN; LYSYLTYROSYLLYSYLASPARTYLALANYLLYSYLGLUTAMYLTRYPTOPHYLLEUCINE; LYSYLTYROSYLLYSYLGLUTAMYLALANYLLYSYLGLUTAMYLTRYPTOPHYLLEUCINE; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS PROTEIN 2C;

ALGORITHM; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; FEMALE; FOOT AND MOUTH DISEASE; FOOT AND MOUTH DISEASE VIRUS; MORTALITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID VECTOR; PRIORITY JOURNAL; SEROTYPE; SPLEEN CELL; VACCINATION; VIREMIA; VIRUS INFECTION;

AMINO ACID SUBSTITUTION; ANIMALS; ANTIGENS, CD44; ANTIGENS, VIRAL; COMPUTATIONAL BIOLOGY; EPITOPES, T-LYMPHOCYTE; FOOT-AND-MOUTH DISEASE; FOOT-AND-MOUTH DISEASE VIRUS; GENE EXPRESSION; GENETIC VECTORS; IMMUNODOMINANT EPITOPES; INTERFERON TYPE II; LYMPHOCYTE SUBSETS; MICE; MICE, INBRED BALB C; PEPTIDES; PLASMIDS; PROTEIN STRUCTURE, TERTIARY; T-LYMPHOCYTES, CYTOTOXIC; VACCINES, DNA; VIRAL NONSTRUCTURAL PROTEINS; VIRAL VACCINES; VIREMIA;

FOOT-AND-MOUTH DISEASE VIRUS; MURINAE;

EID: 33751259349     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.antiviral.2006.07.002     Document Type: Article

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