Detection of a new JAK2 D620E mutation in addition to V617F in a patient with polycythemia vera [17]

Leukemia

Volumn 20, Issue 12, 2006, Pages 2210-2211

  Grunebach F ^a   Bross Bach, U ^a   Kanz, L ^a   Brossart, P ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; GENOMIC DNA; GLUTAMIC ACID; JANUS KINASE 2; PHENYLALANINE; VALINE;

ADULT; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CASE REPORT; CELL ISOLATION; DNA DENATURATION; DNA PURIFICATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LETTER; MALE; MELTING POINT; POINT MUTATION; POLYCYTHEMIA VERA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN;

EID: 33751246214     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2404419     Document Type: Letter

References (8)

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3. James C, Ugo V, Le Couedic JP, Staerk J, Delhommeau F, Lacout C et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005; 434: 1144-1148.
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8. Schnittger S, Bacher U, Kern W, Schroder M, Haferlach T, Schoch C. Report on two novel nucleotide exchanges in the JAK2 pseudokinase domain: D620E and E627E. Leukemia 2006, [E-pub ahead of print].