Partial C-fiber ablation modulates diphenylmethane-4,4′-diisocyanate (MDI)-induced respiratory allergy in Brown Norway rats

Toxicology

Volumn 228, Issue 2-3, 2006, Pages 188-199

  Pauluhn, Jürgen ^a   Vohr, Hans Werner ^a  

^a Institute of Toxicology   (Germany)

Author keywords

Asthma; Capsaicin; Cytokine fingerprinting; Delayed responses; Diphenylmethane diisocyanate; Lung function; MDI; Neutrophilic inflammation; Penh; Respiratory hypersensitivity

Indexed keywords

CAPSAICIN; CHEMOKINE; CYTOKINE; DIPHENYLMETHANE 4,4' DIISOCYANATE; INTERLEUKIN 4; MONOCYTE CHEMOTACTIC PROTEIN 1;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREATHING; CONTROLLED STUDY; INFLAMMATION; LUNG FUNCTION; LUNG LAVAGE; LUNG WEDGE PRESSURE; LUNG WEIGHT; LYMPH NODE; MALE; NERVE FIBER C; NEUTROPHIL; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; RAT; RAT STRAIN; RESPIRATORY TRACT ALLERGY; SENSITIZATION; SENSORY NERVE; STATISTICAL SIGNIFICANCE; TH1 CELL; TH2 CELL;

ADMINISTRATION, INHALATION; AEROSOLS; ANIMALS; AXONS; BODY WEIGHT; BRONCHOALVEOLAR LAVAGE FLUID; CAPSAICIN; CHEMOKINES; CYTOKINES; DIET; HYPERSENSITIVITY, DELAYED; ISOCYANATES; L-LACTATE DEHYDROGENASE; LUNG; LYMPH NODES; NERVE FIBERS, UNMYELINATED; NEUROPEPTIDES; ORGAN SIZE; RATS; RATS, INBRED BN; RATS, WISTAR; REFLEX; RESPIRATORY HYPERSENSITIVITY;

ANIMALIA; RATTUS NORVEGICUS;

EID: 33751210948     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2006.08.031     Document Type: Article

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