Susceptibility to high altitude pulmonary oedema: Role of ACE and ET-1 polymorphisms [2]

Thorax

Volumn 61, Issue 11, 2006, Pages 1011-1012

  Charu, R ^a,c   Stobdan, T ^a   Ram, R B ^a   Khan, A P ^a   Qadar Pasha, M A ^a   Norboo, T ^b   Afrin, F ^c  

^a CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

^b Ladakh Institute of Prevention   (India)

^c HAMDARD UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIN 1; NITRIC OXIDE SYNTHASE;

ALTITUDE DISEASE; CLINICAL FEATURE; GENETIC POLYMORPHISM; GENOTYPE; HIGH ALTITUDE PULMONARY EDEMA; HUMAN; LETTER; LUNG EDEMA; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PULMONARY HYPERTENSION; VASOCONSTRICTION;

ADULT; ALTITUDE SICKNESS; ENDOTHELIN-1; GENE DELETION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MUTAGENESIS, INSERTIONAL; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC; PULMONARY EDEMA;

EID: 33751205920     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.2006.066019     Document Type: Letter

References (6)

1. Mortimer H, Patel S, Peacock AJ. The genetic basis of high-altitude pulmonary oedema. Pharmacol Ther 2004;101:183-92.
2. Qadar Pasha MA, Khan AP, Kumar R, et al. Angiotensin converting enzyme insertion allele in relation to high altitude adaptation. Ann Hum Genet 2001;65:531-6.
3. Rajput C, Najib S, Norboo T, et al. Endothelin-1 gene variants and levels associate with adaptation to hypobaric hypoxia in high-altitude natives. Biochem Biophys Res Commun 2006;341:1218-24.
4. Ahsan A, Charu R, Qadar Pasha MA, et al. eNOS allelic variants at the same locus associate with HAPE and adaptation. Thorax 2004;59:1000-2.
5. Rossi GP, Sacchetto A, Cesari M, et al. Interactions between endothelin-1 and the renin-angiotensin-aldosterone system. Cardiovasc Res 1999;43:300-7.
6. Barton M, Carmona R, Krieger JE, et al. Endothelin regulates angiotensin-converting enzyme in the mouse kidney. J Cardiovasc Pharmacol 2000;36:S244-7.