A study of luteal phase expression of inhibin, activin, and follistatin subunits in the endometrium of women with recurrent miscarriage

Fertility and Sterility

Volumn 86, Issue 6, 2006, Pages 1723-1730

  Prakash, Alka ^a   Li, Tin C ^a   Tuckerman, Elizabeth ^a   Laird, Susan ^b   Wells, Michael ^c   Ledger, William L ^a  

^a JESSOP HOSPITAL FOR WOMEN   (United Kingdom)

^b SHEFFIELD HALLAM UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

activin; Doppler; follistatin; inhibin; luteal phase; Recurrent miscarriage

Indexed keywords

ACTIVIN; ACTIVIN A; ESTRADIOL; FOLLISTATIN; FOLLITROPIN; INHIBIN; INHIBIN B; LUTEINIZING HORMONE; PROGESTERONE; PROTEIN SUBUNIT;

ADULT; ARTICLE; BLOOD FLOW; CLINICAL ARTICLE; COLOR ULTRASOUND FLOWMETRY; CONTROLLED STUDY; ENDOMETRIUM; FEMALE; HISTOLOGY; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; LUTEAL PHASE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPONTANEOUS ABORTION; STATISTICAL SIGNIFICANCE; TERTIARY HEALTH CARE; UNITED KINGDOM; UTERUS BLOOD FLOW;

ABORTION, HABITUAL; ACTIVINS; ADULT; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; ENDOMETRIUM; FEMALE; FOLLISTATIN; HUMANS; INHIBINS; LUTEAL PHASE; PROTEIN SUBUNITS;

EID: 33751197285     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2006.05.040     Document Type: Article

References (33)

1. Crosignani P.G., and Rubin B.L. Recurrent spontaneous abortion. Hum Reprod 6 (1991) 609-610
2. Daya S. Evaluation and management of recurrent spontaneous abortion. Curr Opin Obstet Gynecol 8 (1993) 188-192
3. Katz V.L., and Kuller J.A. Recurrent miscarriage. Am J Perinatol 11 (1994) 386-397
4. Burger H.G., and Igarashi M. Inhibin: definition and nomenclature, including related substances. J Clin Endocrinol Metab 66 (1988) 885-886
5. Mathews L.S. Activin receptors and cellular signaling by the receptor serine kinase family. Endocrinol Rev 15 (1994) 310-325
6. Esch F.S., Shimasaki S., Mercado M., Cooksey K., Ling N., Ying S., et al. Structural characterization of follistatin: a novel follicle-stimulating hormone release-inhibiting polypeptide from the gonad. Mol Endocrinol 1 (1987) 849-855
7. Petraglia F., Florio P., Luisi S., Gallo R., Gadducci A., Vigano P., et al. Expression and secretion of inhibin and activin in normal and neoplastic uterine tissues. High levels of serum activin A in women with endometrial and cervical carcinoma. J Clin Endocrinol Metab 83 (1998) 1194-1200
8. Leung P.H., Salamonsen L.A., and Findlay J.K. Immunolocalization of inhibin and activin subunits in human endometrium across the menstrual cycle. Hum Reprod 13 (1998) 3469-3477
9. Jones K.L., Brauman J.N., Groome N.P., de Kretser D.M., and Phillips D.J. Activin A release into the circulation is an early event in systemic inflammation and precedes the release of follistatin. Endocrinology 141 (2000) 1905-1908
10. Mylonas I., Jeschke U., Wiest I., Hoeing A., Vogl J., Shabani N., et al. Inhibin/activin subunits alpha, beta-A and beta-B are differentially expressed in normal human endometrium throughout the menstrual cycle. Histochem Cell Biol 122 (2004) 461-471
11. Muttukrishna S., Fowler P.A., George L., Groome N.P., and Knight P.G. Changes in peripheral serum levels of total activin A during the human menstrual cycle and pregnancy. J Clin Endocrinol Metab 81 (1996) 3328-3334
12. Muttukrishna S., Fowler P.A., Groome N.P., Mitchell G.G., Robertson W.R., and Knight P.G. Serum concentrations of dimeric inhibin during the spontaneous human menstrual cycle and after treatment with exogenous gonadotrophin. Hum Reprod 9 (1994) 1634-1642
13. Li T.C., Spuijbroek M.D., Tuckerman E., Anstie B., Loxley M., and Laird S. Endocrinological and endometrial factors in recurrent miscarriage. Br J Obstet Gynaecol 107 (2000) 1471-1479
14. Tulppala M., Bjorses U.M., Stenman U.H., Wahlstrom T., and Ylikorkala O. Luteal phase defect in habitual abortion: progesterone in saliva. Fertil Steril 56 (1991) 41-44
15. Noyes R.W., Hertig A.T., and Rock J. Dating the endometrial biopsy. Fertil Steril 1 (1950) 3-25
16. Lessey B.A. Two pathways of progesterone action in the human endometrium: implications for implantation and contraception. Steroids 68 (2003) 809-815
17. Li T.C., and Cooke I.D. Evaluation of the luteal phase. Hum Reprod 6 (1991) 484-499
18. Ozturk O., Bhattacharya S., Saridogan E., Jauniaux E., and Templeton A. Role of utero-ovarian vascular impedance: predictor of ongoing pregnancy in an IVF-embryo transfer programme. Reprod Biomed Online 9 (2004) 299-305
19. Tuckerman E., Laird S.M., Stewart R., Wells M., and Li T.C. Markers of endometrial function in women with unexplained recurrent pregnancy loss: a comparison between morphologically normal and retarded endometrium. Hum Reprod 19 (2004) 196-205
20. Lessey B.A., Yeh I., Castelbaum A.J., Fritz M.A., Ilesanmi A.O., Korzeniowski P., et al. Endometrial progesterone receptors and markers of uterine receptivity in the window of implantation. Fertil Steril 65 (1996) 477-483
21. Nargund G., Doyle P.E., Bourne T.H., Parsons J.H., Cheng W.C., Campbell S., et al. Ultrasound derived indices of follicular blood flow before HCG administration and the prediction of oocyte recovery and preimplantation embryo quality. Hum Reprod 11 (1996) 2512-2517
22. Cheung W., Ng E.H.Y., and Ho P.C. A randomized double-blind comparison of perifollicular vascularity and endometrial receptivity in ovulatory women taking clomiphene citrate at two different times. Hum Reprod 17 (2002) 2881-2884
23. Ng E.H.Y., Chan C.C.W., Tang O.S., Yeung W.S.B., and Ho P.C. Endometrial and subendometrial blood flow measured during early luteal phase by three-dimensional power Doppler ultrasound in excessive ovarian responders. Hum Reprod 19 (2004) 924-931
24. Habara T., Nakatsuka M., Konishi H., Asagiri K., Noguchi S., and Kudo T. Elevated blood flow resistance in uterine arteries of women with unexplained recurrent pregnancy loss. Hum Reprod 17 (2002) 190-194
25. Raine-Fenning N.J., Campbell B.K., Kendall N.R., Clewes J.S., and Johnson I.R. Quantifying the changes in endometrial vascularity throughout the normal menstrual cycle with three-dimensional power Doppler angiography. Hum Reprod 19 (2004) 330-338
26. Murray M.J., Meyer W.R., Zaino R.J., Lessey B.A., Novotny D.B., Ireland K., et al. A critical analysis of the accuracy, reproducibility, and clinical utility of histologic endometrial dating in fertile women. Fertil Steril 81 (2004) 1333-1343
27. Otani T., Minami S., Kokawa K., Shikone T., Yamoto M., and Nakano R. Immunohistochemical localization of activin A in human endometrial tissues during the menstrual cycle and in early pregnancy. Obstet Gynecol 91 (1998) 685-692
28. Jones R.L., Salamonsen L.A., Critchley H.O., Rogers P.A., Affandi B., and Findlay J.K. Inhibin and activin subunits are differentially expressed in endometrial cells and leukocytes during the menstrual cycle, in early pregnancy and in women using progestin-only contraception. Mol Hum Reprod 6 (2000) 1107-1117
29. Jones R.L., Salamonsen L.A., Zhao Y.C., Ethier J.F., Drummond A.E., and Findlay J.K. Expression of activin receptors, follistatin and betaglycan by human endometrial stromal cells; consistent with a role for activins during decidualization. Mol Hum Reprod 8 (2002) 363-374
30. Jones R.L., Salamonsen L.A., and Findlay J.K. Activin A promotes human endometrial stromal cell decidualization in vitro. J Clin Endocrinol Metab 87 (2002) 4001-4004
31. Jones R.L., Salamonsen L.A., and Findlay J.K. Potential roles for endometrial inhibins, activins and follistatin during human embryo implantation and early pregnancy. Trends Endocrinol Metab 13 (2002) 144-150
32. Guo Q., Kumar T.R., Woodruff T., Hadsell L.A., DeMayo F.J., and Matzuk M.M. Overexpression of mouse follistatin causes reproductive defects in transgenic mice. Mol Endocrinol 12 (1998) 96-106
33. Matzuk M.M., Kumar T.R., Vassalli A., Bickenbach J.R., Roop D.R., Jaenisch R., et al. Functional analysis of activins during mammalian development. Nature 374 (1995) 354-356