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Volumn 28, Issue 6, 2006, Pages 560-567

Antifolates as antimycotics?. Connection between the folic acid cycle and the ergosterol biosynthesis pathway in Candida albicans

Author keywords

Antifolates; Candida albicans; Candidosis; Dihydrofolate reductase; Ergosterol; Folic acid

Indexed keywords

AMPHOTERICIN B; ANTIFUNGAL AGENT; ERGOSTEROL; FLUCYTOSINE; FOLIC ACID; FOLIC ACID ANTAGONIST; KETOCONAZOLE; METHOTREXATE; PYRIMETHAMINE; PYRROLE DERIVATIVE; SULFADIAZINE; TERBINAFINE; TRIMETHOPRIM;

EID: 33751185341     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2006.07.012     Document Type: Article
Times cited : (34)

References (20)
  • 1
    • 0033807662 scopus 로고    scopus 로고
    • Upregulation of ERG genes in Candida species by azoles and other sterol biosynthesis inhibitors
    • Henry K.W., Nickels J.T., and Edlind T.D. Upregulation of ERG genes in Candida species by azoles and other sterol biosynthesis inhibitors. Antimicrob Agents Chemother 44 (2000) 2693-2700
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 2693-2700
    • Henry, K.W.1    Nickels, J.T.2    Edlind, T.D.3
  • 3
    • 4644332720 scopus 로고    scopus 로고
    • Posaconazole is a potent inhibitor of sterol 14α-demethylation in yeasts and molds
    • Munayyer H.K., Mann P.A., Chau A.S., et al. Posaconazole is a potent inhibitor of sterol 14α-demethylation in yeasts and molds. Antimicrob Agents Chemother 48 (2004) 3690-3696
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 3690-3696
    • Munayyer, H.K.1    Mann, P.A.2    Chau, A.S.3
  • 4
    • 0025304406 scopus 로고
    • Azole susceptibility and hyphal formation in a cytochrome P-450-deficient mutant of Candida albicans
    • Lees N.D., Broughton M.C., Sanglard D., and Bard M. Azole susceptibility and hyphal formation in a cytochrome P-450-deficient mutant of Candida albicans. Antimicrob Agents Chemother 34 (1990) 831-836
    • (1990) Antimicrob Agents Chemother , vol.34 , pp. 831-836
    • Lees, N.D.1    Broughton, M.C.2    Sanglard, D.3    Bard, M.4
  • 5
    • 0028906887 scopus 로고
    • Cloning of the late genes in the ergosterol biosynthetic pathway of Saccharomyces cerevisiae-a review
    • Lees N.D., Skaggs B., Kirsch D.R., and Bard M. Cloning of the late genes in the ergosterol biosynthetic pathway of Saccharomyces cerevisiae-a review. Lipids 30 (1995) 221-226
    • (1995) Lipids , vol.30 , pp. 221-226
    • Lees, N.D.1    Skaggs, B.2    Kirsch, D.R.3    Bard, M.4
  • 6
    • 0032989082 scopus 로고    scopus 로고
    • Biochemistry and molecular biology of sterol synthesis in Saccharomyces cerevisiae
    • Lees N.D., Bard M., and Kirsch D.R. Biochemistry and molecular biology of sterol synthesis in Saccharomyces cerevisiae. Crit Rev Biochem Mol Biol 34 (1999) 33-47
    • (1999) Crit Rev Biochem Mol Biol , vol.34 , pp. 33-47
    • Lees, N.D.1    Bard, M.2    Kirsch, D.R.3
  • 8
    • 0043270593 scopus 로고    scopus 로고
    • Candida albicans mutations in the ergosterol biosynthetic pathway and resistance to several antifungal agents
    • Sanglard D., Ischer F., Parkinson T., Falconer D., and Bille J. Candida albicans mutations in the ergosterol biosynthetic pathway and resistance to several antifungal agents. Antimicrob Agents Chemother 47 (2003) 2404-2412
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 2404-2412
    • Sanglard, D.1    Ischer, F.2    Parkinson, T.3    Falconer, D.4    Bille, J.5
  • 11
    • 0033398053 scopus 로고    scopus 로고
    • Effect of fluconazole on the growth and adhesion of Candida albicans in the presence of antineoplastic agents
    • Fekete-Forgács K., Kis B., Nagy G., and Lenkey B. Effect of fluconazole on the growth and adhesion of Candida albicans in the presence of antineoplastic agents. J Basic Microbiol 39 (1999) 305-310
    • (1999) J Basic Microbiol , vol.39 , pp. 305-310
    • Fekete-Forgács, K.1    Kis, B.2    Nagy, G.3    Lenkey, B.4
  • 12
    • 33749188749 scopus 로고    scopus 로고
    • Tea polyphenol epigallocatechin-3-gallate inhibits ergosterol synthesis by disturbing folic acid metabolism in Candida albicans
    • Navarro-Martínez M.D., García-Cánovas F., and Rodríguez-López J.N. Tea polyphenol epigallocatechin-3-gallate inhibits ergosterol synthesis by disturbing folic acid metabolism in Candida albicans. J Antimicrob Chemother 57 (2006) 1083-1092
    • (2006) J Antimicrob Chemother , vol.57 , pp. 1083-1092
    • Navarro-Martínez, M.D.1    García-Cánovas, F.2    Rodríguez-López, J.N.3
  • 13
    • 33751189428 scopus 로고    scopus 로고
    • National Committee for Clinical Laboratory Standards. Reference method for broth dilution antifungal susceptibility testing of yeasts. Approved standard. 2nd ed. M27-A2. Wayne, PA: NCCLS; 2002.
  • 14
    • 0031748093 scopus 로고    scopus 로고
    • The metabolism of homocysteine: pathways and regulation
    • Finkelstein J.D. The metabolism of homocysteine: pathways and regulation. Eur J Pediatr 157 Suppl. 2 (1998) S40-S44
    • (1998) Eur J Pediatr , vol.157 , Issue.SUPPL. 2
    • Finkelstein, J.D.1
  • 15
    • 0032771346 scopus 로고    scopus 로고
    • Homocysteine metabolism
    • Selhub J. Homocysteine metabolism. Annu Rev Nutr 19 (1999) 217-246
    • (1999) Annu Rev Nutr , vol.19 , pp. 217-246
    • Selhub, J.1
  • 16
    • 0029926820 scopus 로고    scopus 로고
    • S-adenosylmethionine and methylation
    • Chiang K., Gordon R.K., Tal J., et al. S-adenosylmethionine and methylation. FASEB J 10 (1996) 471-480
    • (1996) FASEB J , vol.10 , pp. 471-480
    • Chiang, K.1    Gordon, R.K.2    Tal, J.3
  • 17
    • 0003859172 scopus 로고
    • 5-Fluorouracil-methotrexate synergy: enhancement of 5-fluorodeoxyuridylate binding to thymidylate synthase by dihydropteroylpolyglutamates
    • Fernandes D.J., and Bertino J.R. 5-Fluorouracil-methotrexate synergy: enhancement of 5-fluorodeoxyuridylate binding to thymidylate synthase by dihydropteroylpolyglutamates. Proc Natl Acad Sci USA 77 (1980) 5663-5667
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 5663-5667
    • Fernandes, D.J.1    Bertino, J.R.2
  • 18
    • 0026567044 scopus 로고
    • Terbinafine: mode of action and properties of the squalene epoxidase inhibition
    • Ryder N.S. Terbinafine: mode of action and properties of the squalene epoxidase inhibition. Br J Dermatol 39 (1992) 2-7
    • (1992) Br J Dermatol , vol.39 , pp. 2-7
    • Ryder, N.S.1
  • 19
    • 0036714075 scopus 로고    scopus 로고
    • Regulation of gene expression by ambient pH in filamentous fungi and yeasts
    • Peñalva M.A., and Arst Jr. H. Regulation of gene expression by ambient pH in filamentous fungi and yeasts. Microbiol Mol Biol Rev 66 (2002) 426-446
    • (2002) Microbiol Mol Biol Rev , vol.66 , pp. 426-446
    • Peñalva, M.A.1    Arst Jr., H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.