Impaired megakaryocytopoiesis in type 2B von Willebrand disease

Blood

Volumn 108, Issue 8, 2006, Pages 2498-2499

  Federici, Augusto B ^a,b  

^a FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); GLYCOPROTEIN IB ALPHA; INOSITOL TRISPHOSPHATE; RISTOCETIN;

AMINO ACID SUBSTITUTION; BLEEDING; CALCIUM HOMEOSTASIS; CD34 SELECTION; CELL MEMBRANE; ELECTRON MICROSCOPY; GENE MUTATION; GENETIC HETEROGENEITY; HEMOSTASIS; HUMAN; MEGAKARYOCYTE; MEGAKARYOPOIESIS; MUTANT; NOTE; PRIORITY JOURNAL; THROMBOCYTE AGGLUTINATION; THROMBOCYTOPENIA; VON WILLEBRAND DISEASE;

EID: 33751167215     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2006-08-037705     Document Type: Note

References (5)

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2. Castaman G, Federici AB, Rodeghiero F, Mannucci PM. von Willebrand's disease in the year 2003: towards the complete identification of gene defects for correct diagnosis and treatment. Haematologica. 2003;88:94-108.
3. 546→Val) associated with an unusual phenotype. Thromb Haemost. 1997;78:1132-1137.
4. Loffredo G, Baronciani L, Noris P, Menna F, Federici AB, Balduini CL. Von Willebrand disease type 2B must be always considered in the differential diagnosis of genetic thrombocytopenias with giant platelets. Platelets. 2006;17:149-152.
5. Baronciani L, Federici AB, Beretta M, Cozzi G, Canciani MT, Mannucci PM. Expression studies on a novel type 2B variant of the von Willebrand factor gene (R1308L) characterized by defective collagen binding. J Thromb Haemost. 2005;3:2689-2694.