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Volumn 34, Issue 23, 1996, Pages 2667-2669

Glc-PC, a new type of glucosidic phospholipid

Author keywords

Glyceraldehyde; Glycosidations; Phospholipids; Proliferation inhibitors; Protein kinase C

Indexed keywords


EID: 33751143880     PISSN: 05700833     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (9)

References (35)
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    • The basal activity was measured without addition of phosphatidylserin/ diolein.
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    • The spontaneously immortalized human keratinocyte cell line HaCaT ([14]) was kindly provided by Dr. N. E. Fusenig (DKFZ Heidelberg, Germany).
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    • note
    • Since the substrate is histone, the measured activity is due predominantly to the "classical" isoforms of protein kinase C (α, β, γ). The test system consists of purified components only and contains no other enzymes besides PKS. A role for Glc-PC as a prodrug with respect to 2-lysophosphatidylcholine (LPC) can thus be ruled out.


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