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The basal activity was measured without addition of phosphatidylserin/ diolein.
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Since the substrate is histone, the measured activity is due predominantly to the "classical" isoforms of protein kinase C (α, β, γ). The test system consists of purified components only and contains no other enzymes besides PKS. A role for Glc-PC as a prodrug with respect to 2-lysophosphatidylcholine (LPC) can thus be ruled out.
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