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Volumn 70, Issue 6, 2006, Pages 2015-2026

2,3-Butanedione monoxime affects cystic fibrosis transmembrane conductance regulator channel function through phosphorylation-dependent and phosphorylation-independent mechanisms: The role of bilayer material properties

Author keywords

[No Author keywords available]

Indexed keywords

CHLORIDE CHANNEL; CYANOGINOSIN; DIACETYL OXIME; FORSKOLIN; GRAMICIDIN; TRANSMEMBRANE CONDUCTANCE REGULATOR;

EID: 33751120420     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.106.026070     Document Type: Article
Times cited : (24)

References (74)
  • 1
    • 2442669014 scopus 로고    scopus 로고
    • Capsaicin potentiates wild-type and mutant cystic fibrosis transmembrane conductance regulator chloride-channel currents
    • Ai T, Bompadre SG, Wang X, Hu S, Li M, and Hwang TC (2004) Capsaicin potentiates wild-type and mutant cystic fibrosis transmembrane conductance regulator chloride-channel currents. Mol Pharmacol 65:1415-1426.
    • (2004) Mol Pharmacol , vol.65 , pp. 1415-1426
    • Ai, T.1    Bompadre, S.G.2    Wang, X.3    Hu, S.4    Li, M.5    Hwang, T.C.6
  • 2
    • 0032055233 scopus 로고    scopus 로고
    • Effects of 2,3-butanedione monoxime (BDM) on calcium channels expressed in Xenopus oocytes
    • Allen TJ., Mikala G, Wu X, and Dolphin AC (1998) Effects of 2,3-butanedione monoxime (BDM) on calcium channels expressed in Xenopus oocytes. J Physiol (Lond) 508:1-14.
    • (1998) J Physiol (Lond) , vol.508 , pp. 1-14
    • Allen, T.J.1    Mikala, G.2    Wu, X.3    Dolphin, A.C.4
  • 3
    • 0020630895 scopus 로고
    • Ion movement through gramicidin a channels. Single-channel measurements at very high potentials
    • Andersen OS (1983) Ion movement through gramicidin A channels. Single-channel measurements at very high potentials. Biophys J 41:119-133.
    • (1983) Biophys J , vol.41 , pp. 119-133
    • Andersen, O.S.1
  • 4
    • 36549058256 scopus 로고    scopus 로고
    • Single-molecule methods for monitoring changes in bilayer elastic properties
    • (2007). in press
    • Andersen OS, Bruno MJ, Sun H, and Koeppe RE 2nd (2007) Single-molecule methods for monitoring changes in bilayer elastic properties. Methods Mol Biol, in press.
    • Methods Mol Biol
    • Andersen, O.S.1    Bruno, M.J.2    Sun, H.3    Koeppe II, R.E.4
  • 5
    • 0031729363 scopus 로고    scopus 로고
    • Ion channels as tools to monitor lipid bilayer-membrane protein interactions: Gramicidin channels as molecular force transducers
    • Andersen OS, Nielsen C, Maer AM, Lundbæk JA, Goulian M, and Koeppe RE 2nd (1999) Ion channels as tools to monitor lipid bilayer-membrane protein interactions: gramicidin channels as molecular force transducers. Methods Enzymol 294:208-224.
    • (1999) Methods Enzymol , vol.294 , pp. 208-224
    • Andersen, O.S.1    Nielsen, C.2    Maer, A.M.3    Lundbæk, J.A.4    Goulian, M.5    Koeppe II, R.E.6
  • 6
    • 4744364651 scopus 로고    scopus 로고
    • Effects of, mechanical uncouplers, diacetyl monoxime, and cytochalasin-D on the electrophysiology of perfused mouse hearts
    • Baker LC, Wolk R, Choi BR, Watkins S, Plan P, Shah A, and Salama G (2004) Effects of, mechanical uncouplers, diacetyl monoxime, and cytochalasin-D on the electrophysiology of perfused mouse hearts. Am J Physiol 287:H1771-H1779.
    • (2004) Am J Physiol , vol.287
    • Baker, L.C.1    Wolk, R.2    Choi, B.R.3    Watkins, S.4    Plan, P.5    Shah, A.6    Salama, G.7
  • 8
    • 0033886092 scopus 로고    scopus 로고
    • Severed molecules functionally define the boundaries of the cystic fibrosis transmembrane conductance regulator's NH(2)-terminal nucleotide binding domain
    • Chan KW, Csanády L, Seto-Young D, Nairn AC, and Gadsby DC (2000) Severed molecules functionally define the boundaries of the cystic fibrosis transmembrane conductance regulator's NH(2)-terminal nucleotide binding domain. J Gen Physiol 116:163-180.
    • (2000) J Gen Physiol , vol.116 , pp. 163-180
    • Chan, K.W.1    Csanády, L.2    Seto-Young, D.3    Nairn, A.C.4    Gadsby, D.C.5
  • 9
    • 0027447303 scopus 로고
    • The effect of oximes on the dihydropyridine-sensitive Ca current of isolated guinea-pig ventricular myocytes
    • Chapman RA (1993) The effect of oximes on the dihydropyridine-sensitive Ca current of isolated guinea-pig ventricular myocytes. Pflueg Arch Eur J Physiol 422:325-331.
    • (1993) Pflueg Arch Eur J Physiol , vol.422 , pp. 325-331
    • Chapman, R.A.1
  • 10
    • 17144456826 scopus 로고    scopus 로고
    • Rapid kinetic analysis of multichannel records by a simultaneous fit to all dwell-time histograms
    • Csanády L (2000) Rapid kinetic analysis of multichannel records by a simultaneous fit to all dwell-time histograms. Biophys J 78:785-799.
    • (2000) Biophys J , vol.78 , pp. 785-799
    • Csanády, L.1
  • 12
    • 0035961166 scopus 로고    scopus 로고
    • Capsaicin-induced depolarisation of mitochondria in dorsal root ganglion neurons is enhanced by vanilloid receptors
    • Dedov VN, Mandadi S, Armati PJ, Verkhratsky A (2001) Capsaicin-induced depolarisation of mitochondria in dorsal root ganglion neurons is enhanced by vanilloid receptors. Neuroscience 103:219-226.
    • (2001) Neuroscience , vol.103 , pp. 219-226
    • Dedov, V.N.1    Mandadi, S.2    Armati, P.J.3    Verkhratsky, A.4
  • 15
    • 0345194306 scopus 로고
    • Lipid bilayer expansion and mechanical disruption in solutions of water-soluble bile acid
    • (Hofmann AF, Paumgartner G, and Stiehl A eds), Kluwer Academic Publishers, Dordrecht
    • Evans E, Rawicz W, and Hofmann AF (1995) Lipid bilayer expansion and mechanical disruption in solutions of water-soluble bile acid, in Bile Acids in Gastroenterology Basic and Clinical Advances (Hofmann AF, Paumgartner G, and Stiehl A eds), pp 59-68, Kluwer Academic Publishers, Dordrecht.
    • (1995) Bile Acids in Gastroenterology Basic and Clinical Advances , pp. 59-68
    • Evans, E.1    Rawicz, W.2    Hofmann, A.F.3
  • 17
    • 0031080062 scopus 로고    scopus 로고
    • Butanedione monoxime promotes voltage-dependent inactivation of L-type calcium channels in heart. Effects on gating currents
    • Ferreira G, Artigas P, Pizarro G, and Brum G (1997) Butanedione monoxime promotes voltage-dependent inactivation of L-type calcium channels in heart. Effects on gating currents. J Mol Cell Cardiol 29:777-787.
    • (1997) J Mol Cell Cardiol , vol.29 , pp. 777-787
    • Ferreira, G.1    Artigas, P.2    Pizarro, G.3    Brum, G.4
  • 18
    • 0035868790 scopus 로고    scopus 로고
    • Action of 2,3-butanedione monoxime on capacitance and electromotility of guinea-pig cochlear outer hair cells
    • Frolenkov GI, Mammano F, and Kachar B (2001) Action of 2,3-butanedione monoxime on capacitance and electromotility of guinea-pig cochlear outer hair cells. J Physiol (Lond) 531:667-676.
    • (2001) J Physiol (Lond) , vol.531 , pp. 667-676
    • Frolenkov, G.I.1    Mammano, F.2    Kachar, B.3
  • 19
    • 0032936619 scopus 로고    scopus 로고
    • Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis
    • Gadsby DC and Nairn AC (1999) Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis. Physiol Rev 79:S77-S107.
    • (1999) Physiol Rev , vol.79
    • Gadsby, D.C.1    Nairn, A.C.2
  • 21
    • 0022080948 scopus 로고
    • Intrinsic curvature hypothesis for biomembrane lipid composition: A role for nonbilayer lipids
    • Gruner SM (1985) Intrinsic curvature hypothesis for biomembrane lipid composition: a role for nonbilayer lipids. Proc Natl Acad Sci USA 82:3665-3669.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 3665-3669
    • Gruner, S.M.1
  • 22
    • 0001117106 scopus 로고
    • Lipid membrane curvature elasticity and protein function
    • (Peliti L ed) Plenum Press, New York
    • Gruner SM (1991) Lipid membrane curvature elasticity and protein function, in Biologically Inspired Physics (Peliti L ed) pp. 127-135, Plenum Press, New York.
    • (1991) Biologically Inspired Physics , pp. 127-135
    • Gruner, S.M.1
  • 23
    • 27744530243 scopus 로고    scopus 로고
    • Capsaicin differentially modulates voltage-activated calcium channel currents in dorsal root ganglion neurones of rats
    • Hagenacker T, Splettstoesser F, Greffrath W, Treede RD, and Busselberg D (2005) Capsaicin differentially modulates voltage-activated calcium channel currents in dorsal root ganglion neurones of rats. Brain Res 1062:74-85.
    • (2005) Brain Res , vol.1062 , pp. 74-85
    • Hagenacker, T.1    Splettstoesser, F.2    Greffrath, W.3    Treede, R.D.4    Busselberg, D.5
  • 24
    • 0026621934 scopus 로고
    • Effect of 2,3-butanedione monoxime on myosin and myofibrillar ATPases. An example of an uncompetitive inhibitor?
    • Herrmann C, Wray J, Travers F, and Barman T (1992) Effect of 2,3-butanedione monoxime on myosin and myofibrillar ATPases. An example of an uncompetitive inhibitor? Biochemistry 31:12227-12232.
    • (1992) Biochemistry , vol.31 , pp. 12227-12232
    • Herrmann, C.1    Wray, J.2    Travers, F.3    Barman, T.4
  • 25
    • 0024602815 scopus 로고
    • Butanedione monoxime suppresses contraction and ATPase activity of rabbit skeletal muscle
    • Higuchi H and Takemori S (1989) Butanedione monoxime suppresses contraction and ATPase activity of rabbit skeletal muscle. J Biochem (Tokyo) 105:638-643.
    • (1989) J Biochem (Tokyo) , vol.105 , pp. 638-643
    • Higuchi, H.1    Takemori, S.2
  • 27
    • 0001268055 scopus 로고
    • Pharmacology of organophosphorus cholinesterase inhibitors
    • Holmstedt B (1959) Pharmacology of organophosphorus cholinesterase inhibitors. Pharmacol Rev 11:567-688.
    • (1959) Pharmacol Rev , vol.11 , pp. 567-688
    • Holmstedt, B.1
  • 28
    • 0027217027 scopus 로고
    • Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A
    • Honkanen RE (1993) Cantharidin, another natural toxin that inhibits the activity of serine/threonine protein phosphatases types 1 and 2A. FEBS Lett 330:283-286.
    • (1993) FEBS Lett , vol.330 , pp. 283-286
    • Honkanen, R.E.1
  • 29
    • 0023018907 scopus 로고
    • Deformation free energy of bilayer membrane and its effect on gramicidin channel lifetime
    • Huang HW (1986) Deformation free energy of bilayer membrane and its effect on gramicidin channel lifetime. Biophys J 50:1061-1070.
    • (1986) Biophys J , vol.50 , pp. 1061-1070
    • Huang, H.W.1
  • 30
    • 0025291674 scopus 로고
    • Direct modulation of secretory chloride channels by arachidonic and other cis unsaturated fatty acids
    • Hwang TC, Guggino SE, and Guggino WB (1990) Direct modulation of secretory chloride channels by arachidonic and other cis unsaturated fatty acids. Proc Natl Acad Sci USA 87:5706-5709.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 5706-5709
    • Hwang, T.C.1    Guggino, S.E.2    Guggino, W.B.3
  • 32
    • 0345254912 scopus 로고    scopus 로고
    • Genistein can modulate channel function by a phosphorylation-independent mechanism: Importance of hydrophobic mismatch and bilayer mechanics
    • Hwang TC, Koeppe RE 2nd, and Andersen OS (2003) Genistein can modulate channel function by a phosphorylation-independent mechanism: importance of hydrophobic mismatch and bilayer mechanics. Biochemistry 42:13646-13658.
    • (2003) Biochemistry , vol.42 , pp. 13646-13658
    • Hwang, T.C.1    Koeppe II, R.E.2    Andersen, O.S.3
  • 33
    • 0028340159 scopus 로고
    • Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysis
    • Hwang TC, Nagel G, Nairn AC, and Gadsby DC (1994) Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysis. Proc Natl Acad Sci USA 91:4698-4702.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4698-4702
    • Hwang, T.C.1    Nagel, G.2    Nairn, A.C.3    Gadsby, D.C.4
  • 34
    • 28744445039 scopus 로고    scopus 로고
    • Effect of genistein on L-type calcium current in guinea pig ventricular myocytes
    • Ji ES, Yin JX, Ma HJ, and He RR (2004) Effect of genistein on L-type calcium current in guinea pig ventricular myocytes. Sheng Li Xue Bao 56:466-470.
    • (2004) Sheng Li Xue Bao , vol.56 , pp. 466-470
    • Ji, E.S.1    Yin, J.X.2    Ma, H.J.3    He, R.R.4
  • 36
    • 0038364008 scopus 로고    scopus 로고
    • Lipid-protein interactions in biological membranes: A structural perspective
    • Lee AG (2003) Lipid-protein interactions in biological membranes: a structural perspective. Biochim Biophys Acta 1612:1-40.
    • (2003) Biochim Biophys Acta , vol.1612 , pp. 1-40
    • Lee, A.G.1
  • 37
    • 33751079805 scopus 로고    scopus 로고
    • The phytoestrogen genistein inhibits calcium spark production and ryanodine binding in adult male ventricular myocytes
    • Liew R, Scoote M, Stagg MA, Collins P, Williams AJ, and MacLeod KT (2004) The phytoestrogen genistein inhibits calcium spark production and ryanodine binding in adult male ventricular myocytes. Biophys J 86:111A.
    • (2004) Biophys J , vol.86
    • Liew, R.1    Scoote, M.2    Stagg, M.A.3    Collins, P.4    Williams, A.J.5    MacLeod, K.T.6
  • 38
    • 0027496762 scopus 로고
    • 2,3-Butanedione monoxime (BDM) inhibition of delayed rectifier DRK1 (Kv2.1) potassium channels expressed in Xenopus oocytes
    • Lopatin AN and Nichols CG (1993) 2,3-Butanedione monoxime (BDM) inhibition of delayed rectifier DRK1 (Kv2.1) potassium channels expressed in Xenopus oocytes. J Pharmacol Exp Ther 265:1011-1016.
    • (1993) J Pharmacol Exp Ther , vol.265 , pp. 1011-1016
    • Lopatin, A.N.1    Nichols, C.G.2
  • 39
    • 0028053841 scopus 로고
    • Lysophospholipids modulate channel function by altering the mechanical properties of lipid bilayers
    • Lundbæk JA and Andersen OS (1994) Lysophospholipids modulate channel function by altering the mechanical properties of lipid bilayers. J Gen Physiol 104:645-673.
    • (1994) J Gen Physiol , vol.104 , pp. 645-673
    • Lundbæk, J.A.1    Andersen, O.S.2
  • 40
  • 42
    • 4143140746 scopus 로고    scopus 로고
    • The influence of short-chain alcohols on interfacial tension, mechanical properties, area/molecule, and permeability of fluid lipid bilayers
    • Ly HV and Longo ML (2004) The influence of short-chain alcohols on interfacial tension, mechanical properties, area/molecule, and permeability of fluid lipid bilayers. Biophys J 87:1013-1033.
    • (2004) Biophys J , vol.87 , pp. 1013-1033
    • Ly, H.V.1    Longo, M.L.2
  • 45
    • 0021474573 scopus 로고
    • Mattress model of lipid-protein interactions in membranes
    • Mouritsen OG and Bloom M (1984) Mattress model of lipid-protein interactions in membranes. Biophys J 46:141-153.
    • (1984) Biophys J , vol.46 , pp. 141-153
    • Mouritsen, O.G.1    Bloom, M.2
  • 46
    • 0033737385 scopus 로고    scopus 로고
    • Inclusion-induced bilayer deformations: Effects of monolayer equilibrium curvature
    • Nielsen C and Andersen OS (2000) Inclusion-induced bilayer deformations: effects of monolayer equilibrium curvature. Biophys J 79:2583-2604.
    • (2000) Biophys J , vol.79 , pp. 2583-2604
    • Nielsen, C.1    Andersen, O.S.2
  • 49
    • 0001182731 scopus 로고    scopus 로고
    • Hydration, curvature, and bending elasticity of phospholipid monolayers
    • Rand RP and Parsegian VA (1997) Hydration, curvature, and bending elasticity of phospholipid monolayers. Curr Topics Mem Transp 44:167-189.
    • (1997) Curr Topics Mem Transp , vol.44 , pp. 167-189
    • Rand, R.P.1    Parsegian, V.A.2
  • 50
    • 0000380033 scopus 로고
    • Physical basis of trigger processes and membrane structures
    • (Chapman D ed) Academic Press, London
    • Sackmann E (1984) Physical basis of trigger processes and membrane structures, in Biological Membranes (Chapman D ed) pp 105-143, Academic Press, London.
    • (1984) Biological Membranes , pp. 105-143
    • Sackmann, E.1
  • 51
    • 0029548431 scopus 로고
    • Oxime depression of the fast sodium current in myocardial cells
    • Sada H, Ban T, and Sperelakis N (1995) Oxime depression of the fast sodium current in myocardial cells. Arch Int Pharmacodyn Ther 330:319-331.
    • (1995) Arch Int Pharmacodyn Ther , vol.330 , pp. 319-331
    • Sada, H.1    Ban, T.2    Sperelakis, N.3
  • 52
    • 0037010863 scopus 로고    scopus 로고
    • Interaction of genistein with the mitochondrial electron transport chain results in opening of the membrane transition pore
    • Salvi M, Brunati AM, Clari G, Toninello A (2002) Interaction of genistein with the mitochondrial electron transport chain results in opening of the membrane transition pore. Biochim Biophys Acta 1556:187-196.
    • (2002) Biochim Biophys Acta , vol.1556 , pp. 187-196
    • Salvi, M.1    Brunati, A.M.2    Clari, G.3    Toninello, A.4
  • 53
    • 0024339942 scopus 로고
    • Induction of conductance heterogeneity in gramicidin channels
    • Sawyer DB, Koeppe RE 2nd, and Andersen OS (1989) Induction of conductance heterogeneity in gramicidin channels. Biochemistry 28:6571-6583.
    • (1989) Biochemistry , vol.28 , pp. 6571-6583
    • Sawyer, D.B.1    Koeppe II, R.E.2    Andersen, O.S.3
  • 54
    • 0025343395 scopus 로고
    • Gramicidin single-channel properties show no solvent-history dependence
    • Sawyer DB, Koeppe RE 2nd, and Andersen OS (1990) Gramicidin single-channel properties show no solvent-history dependence. Biophys J 57:515-523.
    • (1990) Biophys J , vol.57 , pp. 515-523
    • Sawyer, D.B.1    Koeppe II, R.E.2    Andersen, O.S.3
  • 55
    • 0033679854 scopus 로고    scopus 로고
    • 2+-induced NADH formation and inhibits electron transport in rat hearts
    • 2+-induced NADH formation and inhibits electron transport in rat hearts. Am J Physiol 279:H1839-H1848.
    • (2000) Am J Physiol , vol.279
    • Scaduto Jr., R.C.1    Grotyohann, L.W.2
  • 56
    • 0028237855 scopus 로고
    • Multiple effects of 2,3-butanedione monoxime
    • Sellin LC and McArdle JJ (1994) Multiple effects of 2,3-butanedione monoxime. Pharmacol Toxicol 74:305-313.
    • (1994) Pharmacol Toxicol , vol.74 , pp. 305-313
    • Sellin, L.C.1    McArdle, J.J.2
  • 57
    • 0028238355 scopus 로고
    • The modulation of protein kinase C activity by membrane lipid bilayer structure
    • Slater SJ, Kelly MB, Taddeo FJ, Rubin E, and Stubbs CD (1994) The modulation of protein kinase C activity by membrane lipid bilayer structure. J Biol Chem 269:17160-17165.
    • (1994) J Biol Chem , vol.269 , pp. 17160-17165
    • Slater, S.J.1    Kelly, M.B.2    Taddeo, F.J.3    Rubin, E.4    Stubbs, C.D.5
  • 58
    • 0028359669 scopus 로고
    • + channels in isolated mouse pancreatic beta-cells by 2,3-butanedione monoxime
    • + channels in isolated mouse pancreatic beta-cells by 2,3-butanedione monoxime. Br J Pharmacol 112:143-149.
    • (1994) Br J Pharmacol , vol.112 , pp. 143-149
    • Smith, P.A.1    Williams, B.A.2    Ashcroft, F.M.3
  • 59
    • 33750881068 scopus 로고    scopus 로고
    • BDM drives protein dephosphorylation and inhibits adenine nucleotide exchange in cardiomyocytes
    • Stapleton MT, Fuchsbauer CM, and Allshire AP (1998) BDM drives protein dephosphorylation and inhibits adenine nucleotide exchange in cardiomyocytes. Am J Physiol 275:H1260-H1266.
    • (1998) Am J Physiol , vol.275
    • Stapleton, M.T.1    Fuchsbauer, C.M.2    Allshire, A.P.3
  • 60
    • 29244437861 scopus 로고    scopus 로고
    • The cystic fibrosis transmembrane conductance regulator is regulated by a direct interaction with the protein phosphatase 2A
    • Thellin WR, Kesimer M, Tarran R, Kreda SM, Grubb BR, Sheehan JK, Stutts MJ, and Milgram SL (2005) The cystic fibrosis transmembrane conductance regulator is regulated by a direct interaction with the protein phosphatase 2A. J Biol Chem 280:41512-41520.
    • (2005) J Biol Chem , vol.280 , pp. 41512-41520
    • Thellin, W.R.1    Kesimer, M.2    Tarran, R.3    Kreda, S.M.4    Grubb, B.R.5    Sheehan, J.K.6    Stutts, M.J.7    Milgram, S.L.8
  • 61
    • 0037318953 scopus 로고    scopus 로고
    • Caveat experimentor-is your myosin really inhibited?
    • Titus MA (2003) Caveat experimentor-is your myosin really inhibited? Nat Cell Biol 5:95.
    • (2003) Nat Cell Biol , vol.5 , pp. 95
    • Titus, M.A.1
  • 62
    • 0033010266 scopus 로고    scopus 로고
    • 2+ release channels (ryanodine receptors) of cardiac and skeletal muscle
    • 2+ release channels (ryanodine receptors) of cardiac and skeletal muscle. J Membr Biol 169:189-198.
    • (1999) J Membr Biol , vol.169 , pp. 189-198
    • Tripathy, A.1    Xu, L.2    Pasek, D.A.3    Meissner, G.4
  • 63
    • 0030975525 scopus 로고    scopus 로고
    • Reversible blockade of gap junctional communication by 2,3-butanedione monoxime in rat cardiac myocytes
    • Verrecchia F and Herve JC (1997) Reversible blockade of gap junctional communication by 2,3-butanedione monoxime in rat cardiac myocytes. Am J Physiol 272:C875-C885.
    • (1997) Am J Physiol , vol.272
    • Verrecchia, F.1    Herve, J.C.2
  • 65
    • 0036384724 scopus 로고    scopus 로고
    • Improved right heart function after myocardial preservation with 2,3-butanedione 2-monoxime in a porcine model of allogenic heart transplantation
    • Warnecke G, Schulze B, Hagl C, Haverich A, and Klima U (2002) Improved right heart function after myocardial preservation with 2,3-butanedione 2-monoxime in a porcine model of allogenic heart transplantation. J Thorac Cardiovasc Surg 123:81-88.
    • (2002) J Thorac Cardiovasc Surg , vol.123 , pp. 81-88
    • Warnecke, G.1    Schulze, B.2    Hagl, C.3    Haverich, A.4    Klima, U.5
  • 66
    • 0031283371 scopus 로고    scopus 로고
    • Does tyrosine kinase modulate delayed-rectifier K channels in guinea pig ventricular cells?
    • Washizuka T, Horie M, Obayashi K, and Sasayama S (1997) Does tyrosine kinase modulate delayed-rectifier K channels in guinea pig ventricular cells? Heart Vessels Suppl 12:173-174.
    • (1997) Heart Vessels Suppl , vol.12 , pp. 173-174
    • Washizuka, T.1    Horie, M.2    Obayashi, K.3    Sasayama, S.4
  • 70
    • 0029077384 scopus 로고
    • + current of rat ventricular myocytes
    • + current of rat ventricular myocytes. Life Sci 57:335-343.
    • (1995) Life Sci , vol.57 , pp. 335-343
    • Xiao, Y.F.1    McArdle, J.J.2
  • 71
    • 0030607205 scopus 로고    scopus 로고
    • 2,3-Butanedione monoxime modifies the glycine-gated chloride current of acutely isolated murine hypothalamic neurons
    • Ye JH and McArdle JJ (1996) 2,3-Butanedione monoxime modifies the glycine-gated chloride current of acutely isolated murine hypothalamic neurons. Brain Res 735:20-29.
    • (1996) Brain Res , vol.735 , pp. 20-29
    • Ye, J.H.1    McArdle, J.J.2
  • 73
    • 0038506486 scopus 로고    scopus 로고
    • Genistein directly blocks glycine receptors of rat neurons freshly isolated from the ventral tegmental area
    • Zhu L, Jiang ZL, Krnjevic K, Wang FS, and Ye JH (2003) Genistein directly blocks glycine receptors of rat neurons freshly isolated from the ventral tegmental area. Neuropharmacology 45:270-280.
    • (2003) Neuropharmacology , vol.45 , pp. 270-280
    • Zhu, L.1    Jiang, Z.L.2    Krnjevic, K.3    Wang, F.S.4    Ye, J.H.5


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