The effect of STAT1 antisense oligonucleotides on lung fibroblast proliferation and hydroxyproline secretion

Zhonghua Jiehe he Huxi Zazhi

Volumn 28, Issue 10, 2005, Pages 709-713

  Fan, Xian Ming ^a   Liu, Chun Tao ^b   Zhan, Xiao Qin ^b   Xiong, Ying ^b   Feng, Yu Lin ^b   Wang, Zeng Li ^b  

^a SOUTHWEST MEDICAL UNIVERSITY   (China)

^b NONE

Author keywords

Antisense; Lung fibroblast; Macrophages, alveolar; Oligonucleotides; Pulmonary fibrosis; STAT1

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; HYDROXYPROLINE; INTERCELLULAR ADHESION MOLECULE 1; STAT1 PROTEIN; STAT1 PROTEIN, RAT;

ANIMAL; ARTICLE; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECT; FEMALE; FIBROBLAST; LUNG; LUNG ALVEOLUS MACROPHAGE; METABOLISM; RAT; SECRETION; WISTAR RAT;

ANIMALS; CELL PROLIFERATION; FEMALE; FIBROBLASTS; HYDROXYPROLINE; INTERCELLULAR ADHESION MOLECULE-1; LUNG; MACROPHAGES, ALVEOLAR; OLIGONUCLEOTIDES, ANTISENSE; RATS; RATS, WISTAR; STAT1 TRANSCRIPTION FACTOR;

EID: 33751115494     PISSN: 10010939     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Green FH. Overview of pulmonary fibrosis. Chest, 2002, 122(6 Suppl):334S-339S.
2. American Thoracic Society (ATS). Idiopathic pulmonary fibrosis: diagnosis and treatment. Am J Respir Crit Care Med, 2000, 161: 646-664.
3. Rijcken E, Krieglstein CF, Anthoni C, et al. ICAM-1 and VCAM-1 antisense oligonucleotides attenuate in vivo leucocyte adherence and inflammation in rat inflammatory bowel disease. Gut, 2002, 51: 529-535.
4. Bromberg J, Darnell JE Jr. The role of STATs in transcriptional control and their impact on cellular function. Oncogene, 2000, 19: 2468-2473.
5. Walter MJ, Look DC, Tidwell RM, et al. Targeted inhibition of interferon-gamma-dependent intercellular adhesion molecule-1 (ICAM-1) expression using dominant-negative stall. J Biol Chem, 1997, 272:28582-28589.
6. Kvale D, Brandtzaeg P. Immune modulation of adhesion molecules ICAM-1 (CD54) and LFA-3 (CD58) in human hepatocytic cell lines. J Hepatol, 1993, 17:347-352.
7. Gordon JR, Burd PR, Galli SJ. Mast cells as a source of multifunctional cytokines. Immunol Today, 1990, 11:458-464.
8. Tani K, Yasuoka S, Ogushi F, et al. Thrombin enhances lung fibroblast proliferation in bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol, 1991, 5:34-40.
9. Raghu G, Chan YY, Rusch V, et al. Differential proliferation of fibroblasts cultured from normal and fibrotic human lungs. Am Rev Respir Dis, 1988, 138:703-708.
10. Hernnas J, Nettelbladt O, Bjermer L, et al. Alveolar accumulation of fibronectin and hyaluronan precedes bleomycin-induced pulmonary fibrosis in the rat. Eur Respir J, 1992, 5:404-410.