Puzzling through fragment-based drug design

Nature Chemical Biology

Volumn 2, Issue 12, 2006, Pages 658-659

  Hajduk, Philip J ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAMASE; LEAD; LIGAND;

BINDING AFFINITY; BINDING SITE; CHEMICAL MODIFICATION; DRUG BINDING; DRUG DESIGN; DRUG SCREENING; HIGH THROUGHPUT SCREENING; MOLECULAR RECOGNITION; MOLECULAR WEIGHT; PRIORITY JOURNAL; RECEPTOR BINDING; SHORT SURVEY;

EID: 33751112979     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio1206-658     Document Type: Short Survey

References (5)

1. Erlanson, D.A., McDowell, R.S. & O'Brien, T. J. Med. Chem. 47, 3463-3482 (2004).
2. Hajduk, P.J., Huth, J.R. & Sun, C. Methods and Principles in Medicinal Chemistry 34, 181-192 (2006).
3. Hajduk, P.J., Huth, J.R. & Fesik, S.W. J. Med. Chem. 48, 2518-2525 (2005).
4. Babaoglu, K. & Shoichet, B.K. Nat. Chem. Biol. 2, 720-723 (2006).
5. Hann, M.M., Leach, A.R. & Harper, G. J. Chem. Inf. Comput. Sci. 41, 856-864 (2001).