Gene transfection of Livin isoforms into A549 cell line and its effect on cell growth and sensitivity to chemotherapy and radiotherapy

Zhonghua Jiehe he Huxi Zazhi

Volumn 28, Issue 12, 2005, Pages 836-840

  Sun, Jian Guo ^a   Liao, Rong Xia ^a   Chen, Zheng Tang ^a   Wang, Zhi Xin ^a   Zhang, Qing ^a   Hu, Yi De ^a   Wang, Dong Lin ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Carcinoma, non small cell lung; Drug resistance, neoplasm; Gene transfer techniques; Livin

Indexed keywords

BIRC7 PROTEIN, HUMAN; INHIBITOR OF APOPTOSIS PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR PROTEIN;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; DRUG RESISTANCE; GENETIC TRANSFECTION; GENETICS; HUMAN; TUMOR CELL LINE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG RESISTANCE, NEOPLASM; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; NEOPLASM PROTEINS; TRANSFECTION;

EID: 33751105534     PISSN: 10010939     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

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2. Kasof GM, Gomes BC. Livin, a novel inhibitor of apoptosis protein family member. J Biol Chem, 2001, 276:3238-3246.
3. Ashhab Y, Alian A, Polliack A, et al. Two splicing variants of a new inhibitor of apoptosis gene with different biological properties and tissue distribution pattern. FEBS Lett, 2001, 495:56-60.
4. Vucic D, Stennicke HR, Pisabarro MT, et al. ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas. Curr Biol, 2000, 10:1359-1366.
5. Yagihashi A, Asanuma K, Tsuji N, et al. Detection of anti-livin antibody in gastrointestinal cancer patients. Clin Chem, 2003, 49:1206-1208.
6. Gazzaniga P, Gradilone A, Giuliani L, et al. Expression and prognostic significance of LIVIN, SURVFVIN and other apoptosis-related genes in the progression of superficial bladder cancer. Ann Oncol, 2003, 14:85-90.
7. Crnkovic-Mertens I, Hoppe-Seyler F, Butz K. Induction of apoptosis in tumor cells by siRNA-mediated silencing of the livin/ML-IAP/KIAP gene. Oncogene, 2003, 22:8330-8336.