Beneficial effects of the glutamate-modulating agent riluzole on disordered eating and pathological skin-picking behaviors [13]

Journal of Clinical Psychopharmacology

Volumn 26, Issue 6, 2006, Pages 685-687

  Sasso, David A ^a   Kalanithi, Paul S A ^a   Trueblood, Kevin V ^a   Pittenger, Christopher ^a   Kelmendi, Ben ^a   Wayslink, Suzanne ^a   Malison, Robert T ^a   Krystal, John H ^a   Coric, Vladimir ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARIPIPRAZOLE; CITALOPRAM; CLOMIPRAMINE; DULOXETINE; ESCITALOPRAM; FLUOXETINE; GLUTAMIC ACID; LITHIUM; NEFAZODONE; PAROXETINE; RILUZOLE; RISPERIDONE; VALPROIC ACID; ZIPRASIDONE;

ADULT; ANAMNESIS; BEHAVIOR DISORDER; CASE REPORT; CLINICAL FEATURE; DEPRESSION; DRUG TOLERABILITY; EATING DISORDER; FATIGUE; FEMALE; HUMAN; LABORATORY TEST; LETTER; OBSESSIVE COMPULSIVE DISORDER; PATIENT MONITORING; PRIORITY JOURNAL;

DEPRESSIVE DISORDER, MAJOR; EATING DISORDERS; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; HUMANS; MIDDLE AGED; OBSESSIVE-COMPULSIVE DISORDER; PSYCHIATRIC STATUS RATING SCALES; RILUZOLE; SELF-INJURIOUS BEHAVIOR; SKIN; TREATMENT OUTCOME;

EID: 33751082088     PISSN: 02710749     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.jcp.0000245567.29531.d6     Document Type: Letter

References (15)

1. Krystal JH, Sanacora G, Blumberg H, et al. Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments. Mol Psychiatry. 2002;7(suppl 1):S71-S80.
2. Pittenger C, Krystal JH, Coric V. Glutamate-modulating drugs as novel pharmacotherapeutic agents in the treatment of obsessive-compulsive disorder. NeuroRx. 2006;3(1):69-81.
3. Zarate CA Jr, Payne JL, Quiroz J, et al. An open-label trial of riluzole in patients with treatment-resistant major depression. Am J Psychiatry. 2004;161(1):171-174.
4. Coric V, Taskiran S, Pittenger C, et al. Riluzole augmentation in treatment-resistant obsessive-compulsive disorder: an open-label trial. Biol Psychiatry. 2005;58(5):424-428.
5. Keuthen NJ, Deckersbach T, Wilhelm S, et al. The Skin Picking Impact Scale (SPIS): scale development and psychometric analyses. Psychosomatics. 2001;42(5):397-403.
6. Arnold LM, Auchenbach MB, McElroy SL. Psychogenic excoriation. Clinical features, proposed diagnostic criteria, epidemiology and approaches to treatment. CNS Drugs. 2001;15(5):351-359.
7. Burns GA, Ritter RC. The non-competitive NMDA antagonist MK-801 increases food intake in rats. Pharmacol Biochem Behav. 1997;56(1):145-149.
8. Georgescu D, Sears RM, Hommel JD, et al. The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance. J Neurosci. 2005;25(11):2933-2940.
9. Zeni LA, Seidler HB, De Carvalho NA, et al. Glutamatergic control of food intake in pigeons: effects of central injections of glutamate, NMDA, and AMPA receptor agonists and antagonists. Pharmacol Biochem Behav. 2000;65(1):67-74.
10. Mills IH, Park GR, Manara AR, et al. Treatment of compulsive behaviour in eating disorders with intermittent ketamine infusions. QJM. 1998;91(7):493-503.
11. McElroy SL, Arnold LM, Shapira NA, et al. Topiramate in the treatment of binge eating disorder associated with obesity: a randomized, placebo-controlled trial. Am J Psychiatry. 2003;160(2):255-261.
12. De Bernardi C, Ferraris S, D'Innella P, et al. Topiramate for binge eating disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2005;29(2):339-341.
13. Kalivas PW, Volkow N, Seamans J. Unmanageable motivation in addiction: a pathology in prefrontal-accumbens glutamate transmission. Neuron. 2005;45(5):647-650.
14. Pittenger C, Krystal JH, Coric V. Initial evidence of the beneficial effects of glutamate-modulating agents in the treatment of self-injurious behavior associated with borderline personality disorder. J Clin Psychiatry. 2005;66(11):1492-1493.
15. Coric V, Kelmendi BA, Pittenger C, et al. Beneficial effects of the antiglutamatergic agent riluzole in a patient diagnosed with trichotillomania. J Clin Psychiatry. In press.