Exaggerated cardiovascular stress responses and impaired β-adrenergic-mediated pressor recovery in obese Zucker rats

Hypertension

Volumn 48, Issue 6, 2006, Pages 1109-1115

  D'Angelo, Gerard ^a   Mintz, James D ^a   Tidwell, John E ^a   Schreihofer, Ann M ^a   Pollock, David M ^a   Stepp, David W ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Arterial pressure; Behavioral stress; Cardiac output; Regional blood flow; Thyroid

Indexed keywords

BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; ISOPRENALINE; PROPRANOLOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; BEHAVIOR; BLOOD PRESSURE REGULATION; CARDIOVASCULAR RESPONSE; CONDUCTANCE; CONTROLLED STUDY; MALE; MEAN ARTERIAL PRESSURE; MESENTERIC ARTERY; NONHUMAN; OBESITY; PRESSOR RESPONSE; PRIORITY JOURNAL; RAT; RAT STRAIN; STATISTICAL SIGNIFICANCE; STRESS; TELEMETRY; VASCULAR RESISTANCE; VASODILATATION;

ANIMALS; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; MALE; OBESITY; RATS; RATS, ZUCKER; RECEPTORS, ADRENERGIC, BETA; RECOVERY OF FUNCTION; STRESS, PSYCHOLOGICAL; VASODILATION;

EID: 33751079358     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000247306.53547.d4     Document Type: Article

References (36)

1. Hall JE, Jones DP, Kuo JJ, da Silva A, Tallam L, Liu J. Impact of the obesity epidemic on hypertension and renal disease. Curr Hypertens Rep. 2003;5:386-392.
2. Hall JE, Brands MW, Henegar JR, Shek EW. Abnormal kidney function as a cause and a consequence of obesity hypertension. Clin Exp Pharmacol Physiol. 1998;25:58-64.
3. Hall JE, Brands MW, Henegar JR. Mechanisms of hypertension and kidney disease in obesity. Ann NY Acad Sci. 1999;892:91-107.
4. Barnes V, Treiber F, Davis H, Kelley T, Strong W. Central adiposity and hemodynamic functioning at rest and during stress in adolescents. Int J Obes (Lond). 1998;22:1079-1083.
5. Sung BH, Wilson MF, Izzo JL, Ramirez L, Dandona P. Moderately obese, insulin-resistant women exhibit abnormal vascular reactivity to stress. Hypertension. 1997;30:848-853.
6. Seematter G, Guenat E, Schneiter P, Cayeux C, Jéquier E, Tappy L. Effects of mental stress on insulin-mediated glucose metabolism and energy expenditure in lean and obese women. Am J Physiol Endocrinol Metab. 2000;279:E799-E805.
7. Davis MC, Twamley EW, Hamilton NA, Swan PD. Body fat distribution and hemodynamic stress responses in premenopausal obese women: a preliminary study. Health Psychol. 1999;18:625-633.
8. Ribeiro MM, Silva AG, Santos NS, Guazzelle I, Matos LN, Trombetta IC, Halpern A, Negrão CE, Villares SM. Diet and exercise training restore blood pressure and vasodilatory responses during physiological maneuvers in obese children. Circulation. 2005;111:1915-1923.
9. Jern S, Bergbrant A, Björntorp P, Hansson L. Relation of central hemodynamics to obesity and body fat distribution. Hypertension. 1992;19:520-527.
10. Steptoe A, Wardle J. Cardiovascular stress responsivity, body mass and abdominal adiposity. Int J Obes (Lond). 2005;29:1329-1337.
11. Agapitov AV, Correia ML, Sinkey CA, Dopp JM, Haynes WG. Impaired skeletal muscle and skin microcirculatory function in human obesity. J Hypertens. 2002;20:1401-1405.
12. Zucker LM, Antoniades HN. Insulin and obesity in the Zucker genetically obese rat "fatty." Endocrinology. 1972;90:12320-12330.
13. Schreihofer AM, Hair CD, Stepp DW. Reduced plasma volume and mesenteric vascular reactivity in obese Zucker rats. Am J Physiol Regul Integr Comp Physiol. 2005;288:R253-R261.
14. Carlson SH, Shelton J, White CR, Wyss JM. Elevated sympathetic activity contributes to hypertension and salt sensitivity in diabetic obese Zucker rats. Hypertension. 2000;35:403-408.
15. Pamidimukkala J, Jandhyala BS. Evaluation of hemodynamics, vascular reactivity and baroceptor compensation in the insulin resistant Zucker obese rats. Clin Exp Hypertens. 1996;18:1089-1104.
16. Romanko OP, Stepp DW. Reduced constrictor reactivity balances impaired vasodilation in the mesenteric circulation of the obese Zucker rat. Am J Physiol Heart Circ Physiol. 2005;289:H2097-H2102.
17. DiBona GF, Jones SY. Analysis of renal sympathetic nerve responses to stress. Hypertension. 1995;25:531-538.
18. Koepke JP, DiBona GF. Central beta-adrenergic receptors mediate renal nerve activity during stress in conscious spontaneously hypertensive rats. Hypertension. 1985;7:350-356.
19. Koepke JP, Jones S, DiBona GF. Stress increases renal nerve activity and decreases sodium excretion in Dahl rats. Hypertension. 1988;11:334-338.
20. Granneman JG. Effects of agonist exposure on the coupling of beta 1 and beta 3 adrenergic receptors to adenylyl cyclase in isolated adipocytes. J Pharmacol Exp Therap. 1992;261:638-642.
21. Guerre-Millo M. Regulation of ob gene and overexpression in obesity. Biomed Pharmacother. 1997;51:318-323.
22. Scheurink AJW, Steffens AB, Roossien B, Balkan B. Sympathoadrenal function in genetically obese Zucker rats. Physiol Behav. 1992;52:679-685.
23. Pacak K, McCarty R, Palkovitz M, Cizza G, Kopin IJ, Goldstein DS, Chrousos GP. Decreased central and peripheral catecholaminergic activation in obese Zucker rats. Endocrinology. 1995;136:4360-4367.
24. Levin BE, Triscari J, Sullivan AC. Abnormal sympatho-adrenal function and plasma catecholamines in obese Zucker rats. Pharmacol Biochem Behav. 1980;13:107-113.
25. Timofeeva E, Picard F, Duclos M, Deshaies Y, Richard D. Neuronal activation and corticotropin-releasing hormone expression in the brain of obese (fa/fa) and lean (fa/?) Zucker rats in response to refeeding. Eur J Neurosci. 2002;15:1013-1029.
26. Edwards E, King JA, Fray J. Hypertens and insulin resistant models have divergent propensities to learned helpless behavior in rodents. Am J Hypertens. 2000;13:659-665.
27. Danzi S, Klein I. Thyroid hormone and the cardiovascular system. Minerva Endocrinologica. 2004;29:139-150.
28. 2- adrenergic receptors. Mol Pharmacol. 2001;60:955-962.
29. Kaprio J, Koskenvuo M, Rita H. Mortality after bereavement: a prospective study of 95,647 persons. Am J Public Health. 1987;77:283-287.
30. Leor J, Poole WK, Kloner RA. Sudden cardiac death triggered by an earthquake. N Engl J Med. 1996;334:413-419.
31. Meisel SR, Kutz I, Dayan KI, Pauzner H, Chetboun I, Arbel Y, David D. Effect of Iraqi missile war on incidence of acute myocardial infarction and sudden death in Israeli civilians. Lancet. 1991;338:660-661.
32. Mittleman MA, Maclure M, Sherwood JB, Mulry RP, Tofler GH, Jacobs SC, Friedman R, Benson H, Muller JE. Triggering of acute myocardial infarction onset by episodes of anger. Circulation. 1995;92:1720-1725.
33. Light KC, Dolan CA, Davis MR, Sherwood A. Cardiovascular responses to an active coping challenge as predictors of blood pressure patterns 10 to 15 years later. Psychosom Med. 1992;54:217-230.
34. Matthews KA, Woodall KL, Allen MT. Cardiovascular reactivity to stress predicts future blood pressure status. Hypertension. 1993;22:479-485.
35. Gerin W, Pickering TG. Association between delayed recovery of blood pressure after acute mental stress and parental history of hypertension. J Hypertens. 1995;13:603-610.
36. Schuler JL, O'Brien WH. Cardiovascular recovery from stress and hypertension risk: a meta-analytic review. Psychophysiol. 1997;34:649-659.