Pharmacokinetics of orally administered tetrahydrobiopterin in patients with phenylalanine hydroxylase deficiency

Journal of Inherited Metabolic Disease

Volumn 29, Issue 6, 2006, Pages 725-731

  Zurfluh M R ^a   Fiori, L ^b   Fiege, B ^a   Ozen, I ^c   Demirkol, M ^c   Gartner K H ^a   Thony B ^a   Giovannini, M ^b   Blau, Nenad ^a  

^a UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^b Azienda Ospedaliera San Paolo   (Italy)

^c ISTANBUL UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN; PHENYLALANINE 4 MONOOXYGENASE; TETRAHYDROBIOPTERIN;

AREA UNDER THE CURVE; ARTICLE; CLINICAL PROTOCOL; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; DISEASE SEVERITY; DOSE RESPONSE; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG DOSE REGIMEN; DRUG ELIMINATION; GENOTYPE; HUMAN; HYPERPHENYLALANINEMIA; LOADING TEST; MAJOR CLINICAL STUDY; PHENOTYPE; PHENYLKETONURIA; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; AMINO ACID METABOLISM, INBORN ERRORS; AREA UNDER CURVE; BIOPTERIN; GENOTYPE; HUMANS; KINETICS; PHENOTYPE; PHENYLALANINE; PHENYLALANINE HYDROXYLASE; TIME FACTORS;

EID: 33751064142     PISSN: 01418955     EISSN: 15732665     Source Type: Journal    
DOI: 10.1007/s10545-006-0425-6     Document Type: Article

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