메뉴 건너뛰기




Volumn 12, Issue SUPPL. 7, 2006, Pages 84-90

Current experience with itraconazole in neutropenic patients: A concise overview of pharmacological properties and use in prophylactic and empirical antifungal therapy

Author keywords

Antifungal prophylaxis; Empirical antimycotic; Invasive fungal infections; Itraconazole

Indexed keywords

AMPHOTERICIN B; AMPHOTERICIN B LIPID COMPLEX; ASTEMIZOLE; CALCIUM CHANNEL BLOCKING AGENT; CARBAMAZEPINE; CASPOFUNGIN; CISAPRIDE; CYCLODEXTRIN; CYCLOSPORIN; DIGOXIN; FLUCONAZOLE; ISONIAZID; ITRACONAZOLE; MIDAZOLAM; PHENOBARBITAL; PHENYTOIN; RIFAMPICIN; TERFENADINE; TRIAZOLAM; TRIAZOLE DERIVATIVE; TSUKUBAENOLIDE; VORICONAZOLE;

EID: 33751050958     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1111/j.1469-0691.2006.01609.x     Document Type: Review
Times cited : (18)

References (54)
  • 2
    • 0023173133 scopus 로고
    • Activity of orally, topically, and parenterally administered itraconazole in the treatment of superficial and deep mycoses: Animal models
    • Van Cutsem J, Van Gerven F, Janssen PA. Activity of orally, topically, and parenterally administered itraconazole in the treatment of superficial and deep mycoses: Animal models. Rev Infect Dis 1987; 9 (suppl 1): S15-S32.
    • (1987) Rev Infect Dis , vol.9 , Issue.SUPPL. 1
    • Van Cutsem, J.1    Van Gerven, F.2    Janssen, P.A.3
  • 3
    • 0024517330 scopus 로고
    • Itraconazole: A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in superficial and systemic mycoses
    • Grant SM, Clissod SP. Itraconazole: A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in superficial and systemic mycoses. Drugs 1989; 37: 310-344.
    • (1989) Drugs , vol.37 , pp. 310-344
    • Grant, S.M.1    Clissod, S.P.2
  • 4
    • 0026582739 scopus 로고
    • Plasma itraconazole concentrations in neutropenic patients after repeated high-dose treatment
    • Persat F, Marzullo C, Guyotat D, Rochet MJ, Piens MA. Plasma itraconazole concentrations in neutropenic patients after repeated high-dose treatment. Eur J Cancer 1992; 28A: 838-841.
    • (1992) Eur J Cancer , vol.28 A , pp. 838-841
    • Persat, F.1    Marzullo, C.2    Guyotat, D.3    Rochet, M.J.4    Piens, M.A.5
  • 5
    • 0024847184 scopus 로고
    • The clinical pharmacokinetics of itraconazole: An overview
    • Heykants J, van Peer A, van de Velde V et al. The clinical pharmacokinetics of itraconazole: An overview. Mycoses 1989; 32 (suppl 1): 67-87.
    • (1989) Mycoses , vol.32 , Issue.SUPPL. 1 , pp. 67-87
    • Heykants, J.1    van Peer, A.2    van de Velde, V.3
  • 6
    • 0030451280 scopus 로고    scopus 로고
    • Antifungal prophylaxis with itraconazole in neutropenic patients: Pharmacological, microbiological and clinical aspects
    • Glasmacher A, Molitor E, Mezger J, Marklein G. Antifungal prophylaxis with itraconazole in neutropenic patients: Pharmacological, microbiological and clinical aspects. Mycoses 1996; 39: 249-258.
    • (1996) Mycoses , vol.39 , pp. 249-258
    • Glasmacher, A.1    Molitor, E.2    Mezger, J.3    Marklein, G.4
  • 7
    • 0033233203 scopus 로고    scopus 로고
    • Itraconazole trough levels in antifungal prophylaxis with six different dosing regimens using hydroxypropyl-cyclodextrin oral solution or coated-pellet capsules
    • Glasmacher A, Hahn C, Molitor E, Sauerbruch T, Schmidt-Wolf IGH. Itraconazole trough levels in antifungal prophylaxis with six different dosing regimens using hydroxypropyl-cyclodextrin oral solution or coated-pellet capsules. Mycoses 1999; 42: 591-600.
    • (1999) Mycoses , vol.42 , pp. 591-600
    • Glasmacher, A.1    Hahn, C.2    Molitor, E.3    Sauerbruch, T.4    Schmidt-Wolf, I.G.H.5
  • 9
    • 0031808362 scopus 로고    scopus 로고
    • Enhanced bioavailability of itraconazole in hydroxypropyl-β-cyclodextrin solution versus capsules in healty volunteers
    • Barone JA, Moskovitz BL, Guarnieri J et al. Enhanced bioavailability of itraconazole in hydroxypropyl-β-cyclodextrin solution versus capsules in healty volunteers. Antimicrob Agents Chemother 1998; 42: 1862-1865.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 1862-1865
    • Barone, J.A.1    Moskovitz, B.L.2    Guarnieri, J.3
  • 10
    • 0034955068 scopus 로고    scopus 로고
    • Itraconazole oral solution and intravenous formulations: A review of pharmacokinetics and pharmacodynamics
    • Willems L, Van Der GR, de Beule K. Itraconazole oral solution and intravenous formulations: A review of pharmacokinetics and pharmacodynamics. J Clin Pharm Ther 2001; 26: 159-169.
    • (2001) J Clin Pharm Ther , vol.26 , pp. 159-169
    • Willems, L.1    Van Der, G.R.2    de Beule, K.3
  • 11
    • 0028819881 scopus 로고
    • Multiple dose pharmacokinetics of an oral solution of itraconazole in patients receiving chemotherapy for acute myeloid leukaemia
    • Prentice AG, Warnock DW, Johnson SA, Taylor PC, Oliver DA. Multiple dose pharmacokinetics of an oral solution of itraconazole in patients receiving chemotherapy for acute myeloid leukaemia. J Antimicrob Chemother 1995; 36: 657-663.
    • (1995) J Antimicrob Chemother , vol.36 , pp. 657-663
    • Prentice, A.G.1    Warnock, D.W.2    Johnson, S.A.3    Taylor, P.C.4    Oliver, D.A.5
  • 12
    • 0028674170 scopus 로고
    • Multiple dose pharmacokinetics of an oral solution of itraconazole in autologous bone marrow transplant recipients
    • Prentice AG, Warnock DW, Johnson SA, Phillips MJ, Oliver DA. Multiple dose pharmacokinetics of an oral solution of itraconazole in autologous bone marrow transplant recipients. J Antimicrob Chemother 1994; 34: 247-252.
    • (1994) J Antimicrob Chemother , vol.34 , pp. 247-252
    • Prentice, A.G.1    Warnock, D.W.2    Johnson, S.A.3    Phillips, M.J.4    Oliver, D.A.5
  • 13
    • 33751061945 scopus 로고    scopus 로고
    • Prophylaxis of invasive Aspergillus infections with itraconazole in patients with acute leukaemia
    • [abstract]
    • Glasmacher A, Molitor E, Bomba K et al. Prophylaxis of invasive Aspergillus infections with itraconazole in patients with acute leukaemia. Br J Haematol 1996; 93 (suppl 2): 262 [abstract].
    • (1996) Br J Haematol , vol.93 , Issue.SUPPL. 2 , pp. 262
    • Glasmacher, A.1    Molitor, E.2    Bomba, K.3
  • 14
    • 0031605615 scopus 로고    scopus 로고
    • Clinical pharmacology of systemic antifungal agents: A comprehensive review of agents in clinical use, current investigational compounds, and putative targets for antifungal drug development
    • Groll A, Piscitelli S, Walsh TJ. Clinical pharmacology of systemic antifungal agents: A comprehensive review of agents in clinical use, current investigational compounds, and putative targets for antifungal drug development. Adv Pharmacol 1998; 44: 343-501.
    • (1998) Adv Pharmacol , vol.44 , pp. 343-501
    • Groll, A.1    Piscitelli, S.2    Walsh, T.J.3
  • 15
    • 0026690747 scopus 로고
    • Systemically administered antifungal agents: A review of their clinical pharmacology and therapeutic applications
    • Lyman CA, Walsh TJ. Systemically administered antifungal agents: A review of their clinical pharmacology and therapeutic applications. Drugs 1992; 44: 9-35.
    • (1992) Drugs , vol.44 , pp. 9-35
    • Lyman, C.A.1    Walsh, T.J.2
  • 16
    • 0030003444 scopus 로고    scopus 로고
    • Itraconazole: Pharmacology, clinical experience and future development
    • de Beule K. Itraconazole: Pharmacology, clinical experience and future development. Int J Antimicrob Agents 1996; 6: 175-181.
    • (1996) Int J Antimicrob Agents , vol.6 , pp. 175-181
    • de Beule, K.1
  • 17
    • 24144435977 scopus 로고    scopus 로고
    • Making sense of itraconazole pharmacokinetics
    • Prentice AG, Glasmacher A. Making sense of itraconazole pharmacokinetics. J Antimicrob Chemother 2005; 56 (suppl 1): I17-i22.
    • (2005) J Antimicrob Chemother , vol.56 , Issue.SUPPL. 1
    • Prentice, A.G.1    Glasmacher, A.2
  • 19
    • 0023769462 scopus 로고
    • Itraconazole pharmacokinetics in patients with renal dysfunction
    • Boelart J, Schurgers M, Matthys E et al. Itraconazole pharmacokinetics in patients with renal dysfunction. Antimicrob Agents Chemother 1988; 32: 1595-1597.
    • (1988) Antimicrob Agents Chemother , vol.32 , pp. 1595-1597
    • Boelart, J.1    Schurgers, M.2    Matthys, E.3
  • 21
    • 0032418143 scopus 로고    scopus 로고
    • In-vitro activity of voriconazole, itraconazole and amphotericin B against filamentous fungi
    • Johnson EM, Szekely A, Warnock DW. In-vitro activity of voriconazole, itraconazole and amphotericin B against filamentous fungi. J Antimicrob Chemother 1998; 42: 741-745.
    • (1998) J Antimicrob Chemother , vol.42 , pp. 741-745
    • Johnson, E.M.1    Szekely, A.2    Warnock, D.W.3
  • 23
    • 0024916061 scopus 로고
    • Antifungal prophylaxis with itraconazole in prolonged neutropenia: Correlation with plasma levels
    • Boogaerts MA, Verhoef GE, Zachee P, Demuynck H, Verbist L, DeBeule K. Antifungal prophylaxis with itraconazole in prolonged neutropenia: correlation with plasma levels. Mycoses 1989; 32: 103-108.
    • (1989) Mycoses , vol.32 , pp. 103-108
    • Boogaerts, M.A.1    Verhoef, G.E.2    Zachee, P.3    Demuynck, H.4    Verbist, L.5    DeBeule, K.6
  • 24
    • 0024891173 scopus 로고
    • The in vitro antifungal spectrum of itraconazole
    • Van Cutsem J. The in vitro antifungal spectrum of itraconazole. Mycoses 1989; 32: 7-13.
    • (1989) Mycoses , vol.32 , pp. 7-13
    • Van Cutsem, J.1
  • 25
    • 0031893541 scopus 로고    scopus 로고
    • Evaluation of possible correlations between antifungal susceptibilities of filamentous fungi in vitro and antifungal treatment outcomes in animal infections models
    • Odds FC, Van Gerven F, Espinel Ingroff A et al. Evaluation of possible correlations between antifungal susceptibilities of filamentous fungi in vitro and antifungal treatment outcomes in animal infections models. Antimicrob Agents Chemother 1998; 42: 282-288.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 282-288
    • Odds, F.C.1    Van Gerven, F.2    Espinel Ingroff, A.3
  • 26
    • 0028300472 scopus 로고
    • Itraconazole for experimental pulmonary aspergillosis: Comparison with amphotericin B, interaction with cyclosporin A, and correlation between therapeutic response and itraconazole concentrations in plasma
    • Berenguer J, Ali NM, Allende CM et al. Itraconazole for experimental pulmonary aspergillosis: Comparison with amphotericin B, interaction with cyclosporin A, and correlation between therapeutic response and itraconazole concentrations in plasma. Antimicrob Agents Chemother 1994; 38: 1303-1308.
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 1303-1308
    • Berenguer, J.1    Ali, N.M.2    Allende, C.M.3
  • 27
    • 0031052377 scopus 로고    scopus 로고
    • Development of interpretive breakpoints for antifungal susceptibility testing: Conceptual framework and analysis of in vitro-in vivo correlation data for fluconazole, itraconazole, and candida infections. Subcommittee on Antifungal Susceptibility Testing of the National Committee for Clinical Laboratory Standards
    • Rex JH, Pfaller MA, Galgiani JN et al. Development of interpretive breakpoints for antifungal susceptibility testing: Conceptual framework and analysis of in vitro-in vivo correlation data for fluconazole, itraconazole, and candida infections. Subcommittee on Antifungal Susceptibility Testing of the National Committee for Clinical Laboratory Standards. Clin Infect Dis 1997; 24: 235-247.
    • (1997) Clin Infect Dis , vol.24 , pp. 235-247
    • Rex, J.H.1    Pfaller, M.A.2    Galgiani, J.N.3
  • 28
    • 3442892763 scopus 로고    scopus 로고
    • Advances in the molecular and serological diagnosis of invasive fungal infection in haemato-oncology patients
    • McLintock LA, Jones BL. Advances in the molecular and serological diagnosis of invasive fungal infection in haemato-oncology patients. Br J Haematol 2004; 126: 289-297.
    • (2004) Br J Haematol , vol.126 , pp. 289-297
    • McLintock, L.A.1    Jones, B.L.2
  • 29
    • 0035109799 scopus 로고    scopus 로고
    • Aspergillosis case-fatality rate: Systematic review of the literature
    • Lin SJ, Schranz J, Teutsch SM. Aspergillosis case-fatality rate: systematic review of the literature. Clin Infect Dis 2001; 32: 358-366.
    • (2001) Clin Infect Dis , vol.32 , pp. 358-366
    • Lin, S.J.1    Schranz, J.2    Teutsch, S.M.3
  • 30
    • 0141928531 scopus 로고    scopus 로고
    • The European Confederation of Medical Mycology (ECMM) survey of candidaemia in Italy: Antifungal susceptibility patterns of 261 non-albicans Candida isolates from blood
    • Tortorano AM, Rigoni AL, Biraghi E, Prigitano A, Viviani MA. The European Confederation of Medical Mycology (ECMM) survey of candidaemia in Italy: Antifungal susceptibility patterns of 261 non-albicans Candida isolates from blood. J Antimicrob Chemother 2003; 52: 679-682.
    • (2003) J Antimicrob Chemother , vol.52 , pp. 679-682
    • Tortorano, A.M.1    Rigoni, A.L.2    Biraghi, E.3    Prigitano, A.4    Viviani, M.A.5
  • 31
    • 1542438612 scopus 로고    scopus 로고
    • Itraconazole prevents invasive fungal infections in neutropenic patients treated for haematological malignancies: Evidence from a meta-analysis of 3,597 patients
    • Glasmacher A, Prentice AG, Gorschluter M et.al. Itraconazole prevents invasive fungal infections in neutropenic patients treated for haematological malignancies: Evidence from a meta-analysis of 3,597 patients. J Clin Oncol 2003; 21: 4615-4626.
    • (2003) J Clin Oncol , vol.21 , pp. 4615-4626
    • Glasmacher, A.1    Prentice, A.G.2    Gorschluter, M.3
  • 32
    • 24144448601 scopus 로고    scopus 로고
    • Evidence-based review of antifungal prophylaxis in neutropenic patients with haematological malignancies
    • Glasmacher A, Prentice AG. Evidence-based review of antifungal prophylaxis in neutropenic patients with haematological malignancies. J Antimicrob Chemother 2005; 56 (suppl 1): I23-i32.
    • (2005) J Antimicrob Chemother , vol.56 , Issue.SUPPL. 1
    • Glasmacher, A.1    Prentice, A.G.2
  • 33
    • 0034306850 scopus 로고    scopus 로고
    • Prophylactic action of oral fluconazole against fungal infection in neutropenic patients. A meta-analysis of 16 randomized, controlled trials
    • Kanda Y, Yamamoto R, Chizuka A et al. Prophylactic action of oral fluconazole against fungal infection in neutropenic patients. A meta-analysis of 16 randomized, controlled trials. Cancer 2000; 89: 1611-1625.
    • (2000) Cancer , vol.89 , pp. 1611-1625
    • Kanda, Y.1    Yamamoto, R.2    Chizuka, A.3
  • 34
    • 24144435977 scopus 로고    scopus 로고
    • Making sense of itraconazole pharmacokinetics
    • Prentice AG, Glasmacher A. Making sense of itraconazole pharmacokinetics. J Antimicrob Chemother 2005; 56 (suppl 1): I17-i22.
    • (2005) J Antimicrob Chemother , vol.56 , Issue.SUPPL. 1
    • Prentice, A.G.1    Glasmacher, A.2
  • 35
    • 0842328814 scopus 로고    scopus 로고
    • Itraconazole versus fluconazole for prevention of fungal infections in patients receiving allogeneic stem cell transplants
    • Marr KA, Crippa F, Leisenring W et al. Itraconazole versus fluconazole for prevention of fungal infections in patients receiving allogeneic stem cell transplants. Blood 2004; 103: 1527-1533.
    • (2004) Blood , vol.103 , pp. 1527-1533
    • Marr, K.A.1    Crippa, F.2    Leisenring, W.3
  • 36
    • 0842307309 scopus 로고    scopus 로고
    • Cyclophosphamide metabolism is affected by azole antifungals
    • Marr KA, Leisenring W, Crippa F et al. Cyclophosphamide metabolism is affected by azole antifungals. Blood 2004; 103: 1557-1559.
    • (2004) Blood , vol.103 , pp. 1557-1559
    • Marr, K.A.1    Leisenring, W.2    Crippa, F.3
  • 37
    • 0037736664 scopus 로고    scopus 로고
    • Intravenous and oral itraconazole versus intravenous and oral fluconazole for long-term antifungal prophylaxis in allogeneic hematopoietic stem-cell transplant recipients. A multicenter, randomized trial
    • Winston DJ, Maziarz RT, Chandrasekar PH et al. Intravenous and oral itraconazole versus intravenous and oral fluconazole for long-term antifungal prophylaxis in allogeneic hematopoietic stem-cell transplant recipients. A multicenter, randomized trial. Ann Intern Med 2003; 138: 705-713.
    • (2003) Ann Intern Med , vol.138 , pp. 705-713
    • Winston, D.J.1    Maziarz, R.T.2    Chandrasekar, P.H.3
  • 38
    • 4444367711 scopus 로고    scopus 로고
    • Elimination of Aspergillus infection in allogeneic stem cell transplant recipients with long-term itraconazole prophylaxis: Prevention is better than treatment
    • Winston DJ, Emmanouilides C, Bartoni K, Schiller GJ, Paquette R, Territo MC. Elimination of Aspergillus infection in allogeneic stem cell transplant recipients with long-term itraconazole prophylaxis: prevention is better than treatment. Blood 2004; 104: 1581.
    • (2004) Blood , vol.104 , pp. 1581
    • Winston, D.J.1    Emmanouilides, C.2    Bartoni, K.3    Schiller, G.J.4    Paquette, R.5    Territo, M.C.6
  • 40
    • 0842307151 scopus 로고    scopus 로고
    • Empirical antifungal therapy
    • Klastersky J. Empirical antifungal therapy. Int J Antimicrob Agents 2004; 23: 105-112.
    • (2004) Int J Antimicrob Agents , vol.23 , pp. 105-112
    • Klastersky, J.1
  • 41
    • 0019946004 scopus 로고
    • Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia
    • Pizzo PA, Robichaud KJ, Gill FA, Witebsky FG. Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopenia. Am J Med 1982; 72: 101-111.
    • (1982) Am J Med , vol.72 , pp. 101-111
    • Pizzo, P.A.1    Robichaud, K.J.2    Gill, F.A.3    Witebsky, F.G.4
  • 42
    • 0024687690 scopus 로고
    • Empiric antifungal therapy in febrile granulocytopenic patients
    • EORTC International Antimicrobial Therapy Cooperative Group. EORTC International Antimicrobial Therapy Cooperative Group
    • EORTC International Antimicrobial Therapy Cooperative Group. Empiric antifungal therapy in febrile granulocytopenic patients. EORTC International Antimicrobial Therapy Cooperative Group. Am J Med 1989; 86: 668-672.
    • (1989) Am J Med , vol.86 , pp. 668-672
  • 43
    • 0033545538 scopus 로고    scopus 로고
    • Liposomal amphotericin B for empirical therapy in patients with persistent fever and neutropenia
    • Walsh TJ, Finberg R, Arndt C et al. Liposomal amphotericin B for empirical therapy in patients with persistent fever and neutropenia. N Engl J Med 1999; 340: 764-771.
    • (1999) N Engl J Med , vol.340 , pp. 764-771
    • Walsh, T.J.1    Finberg, R.2    Arndt, C.3
  • 44
    • 0033545538 scopus 로고    scopus 로고
    • Liposomal amphotericin B for empirical therapy in patients with persistent fever and neutropenia
    • National Institute of Allergy and Infectious Diseases Mycoses Study Group
    • Walsh TJ, Finberg RW, Arndt C et al. Liposomal amphotericin B for empirical therapy in patients with persistent fever and neutropenia. National Institute of Allergy and Infectious Diseases Mycoses Study Group. N Engl J Med 1999; 340: 764-771.
    • (1999) N Engl J Med , vol.340 , pp. 764-771
    • Walsh, T.J.1    Finberg, R.W.2    Arndt, C.3
  • 45
    • 4644346490 scopus 로고    scopus 로고
    • Caspofungin versus liposomal amphotericin B for empirical antifungal therapy in patients with persistent fever and neutropenia
    • Walsh TJ, Teppler H, Donowitz GR et al. Caspofungin versus liposomal amphotericin B for empirical antifungal therapy in patients with persistent fever and neutropenia. N Engl J Med 2004; 351: 1391-1402.
    • (2004) N Engl J Med , vol.351 , pp. 1391-1402
    • Walsh, T.J.1    Teppler, H.2    Donowitz, G.R.3
  • 46
    • 0035909054 scopus 로고    scopus 로고
    • Intravenous and oral itraconazole versus intravenous amphotericin B deoxycholate as empirical antifungal therapy for persistent fever in neutropenic patients with cancer who are receiving broad-spectrum antibacterial therapy. A randomized, controlled trial
    • Boogaerts M, Winston DJ, Bow EJ et al. Intravenous and oral itraconazole versus intravenous amphotericin B deoxycholate as empirical antifungal therapy for persistent fever in neutropenic patients with cancer who are receiving broad-spectrum antibacterial therapy. A randomized, controlled trial. Ann Intern Med 2001; 135: 412-422.
    • (2001) Ann Intern Med , vol.135 , pp. 412-422
    • Boogaerts, M.1    Winston, D.J.2    Bow, E.J.3
  • 47
    • 33749511722 scopus 로고    scopus 로고
    • Intravenous itraconazole followed by oral itraconazole versus intravenous amphotericin B as empirical antifungal therapy for febrile neutropenic haematological cancer patients
    • [abstract]
    • Ehninger G, Schuler U, Bammer S et al. Intravenous itraconazole followed by oral itraconazole versus intravenous amphotericin B as empirical antifungal therapy for febrile neutropenic haematological cancer patients. Blood 2002; 100 (suppl): 42b [abstract].
    • (2002) Blood , vol.100 , Issue.SUPPL. 42b
    • Ehninger, G.1    Schuler, U.2    Bammer, S.3
  • 48
    • 24144465716 scopus 로고    scopus 로고
    • Strategies for managing systemic fungal infection and the place of itraconazole
    • Potter M. Strategies for managing systemic fungal infection and the place of itraconazole. J Antimicrob Chemother 2005; 56 (suppl 1): i49-i54.
    • (2005) J Antimicrob Chemother , vol.56 , Issue.SUPPL. 1
    • Potter, M.1
  • 49
    • 24144434097 scopus 로고    scopus 로고
    • The place for itraconazole in treatment
    • Maertens J, Boogaerts M. The place for itraconazole in treatment. J Antimicrob Chemother 2005; 56 (suppl 1): I33-i38.
    • (2005) J Antimicrob Chemother , vol.56 , Issue.SUPPL. 1
    • Maertens, J.1    Boogaerts, M.2
  • 50
    • 0035134450 scopus 로고    scopus 로고
    • The cost of treating systemic fungal infections
    • van Gool R. The cost of treating systemic fungal infections. Drugs 2001; 61 (suppl 1): 49-56.
    • (2001) Drugs , vol.61 , Issue.SUPPL. 1 , pp. 49-56
    • van Gool, R.1
  • 51
    • 0037165259 scopus 로고    scopus 로고
    • Voriconazole compared with liposomal amphotericin B for empirical antifungal therapy in patients with neutropenia and persistent fever
    • Walsh TJ, Pappas P, Winston DJ et al. Voriconazole compared with liposomal amphotericin B for empirical antifungal therapy in patients with neutropenia and persistent fever. N Engl J Med 2002; 346: 225-234.
    • (2002) N Engl J Med , vol.346 , pp. 225-234
    • Walsh, T.J.1    Pappas, P.2    Winston, D.J.3
  • 52
    • 0034926627 scopus 로고    scopus 로고
    • Itraconazole versus amphotericin B plus nystatin in the prophylaxis of fungal infections in neutropenic cancer patients
    • Boogaerts M, Maertens J, van Hoof A et al. Itraconazole versus amphotericin B plus nystatin in the prophylaxis of fungal infections in neutropenic cancer patients. J Antimicrob Chemother 2001; 48: 97-103.
    • (2001) J Antimicrob Chemother , vol.48 , pp. 97-103
    • Boogaerts, M.1    Maertens, J.2    van Hoof, A.3
  • 53
    • 33751049592 scopus 로고    scopus 로고
    • Itraconazole i.v. compared to amphotericin B as empirical therapy of neutropenic fever in patients with haematological malignancies
    • [abstract]
    • Ehninger G, Schuler U, Bammer S et al. Itraconazole i.v. compared to amphotericin B as empirical therapy of neutropenic fever in patients with haematological malignancies. Onkologie 2002; 25 (suppl 4): 129 [abstract].
    • (2002) Onkologie , vol.25 , Issue.SUPPL. 4 , pp. 129
    • Ehninger, G.1    Schuler, U.2    Bammer, S.3
  • 54
    • 0032886182 scopus 로고    scopus 로고
    • Breakthrough invasive fungal infections in neutropenic patients after prophylaxis with itraconazole
    • Glasmacher A, Hahn C, Leutner C et al. Breakthrough invasive fungal infections in neutropenic patients after prophylaxis with itraconazole. Mycoses 1999; 42: 443-451.
    • (1999) Mycoses , vol.42 , pp. 443-451
    • Glasmacher, A.1    Hahn, C.2    Leutner, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.