Autologous hematopoietic stem cell transplants that utilize total body irradiation can safely be carried out entirely on an outpatient basis

Bone Marrow Transplantation

Volumn 38, Issue 11, 2006, Pages 757-764

  Stiff, P ^a   Mumby, P ^a   Miler, L ^a   Rodriguez, T ^a   Parthswarthy, M ^a   Kiley, K ^a   Porter, N ^a   Batiste, R ^a   Wojtowitz, S ^a   Lichtenstein, S ^a   Fox Geiman, M ^a   Toor, A ^a  

^a LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CILASTATIN PLUS IMIPENEM; CYCLOPHOSPHAMIDE; ETOPOSIDE; FENTANYL; MELPHALAN; MORPHINE;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; ARTICLE; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; CANCER SURVIVAL; CAREGIVER; CHRONIC LYMPHATIC LEUKEMIA; CHRONIC MYELOID LEUKEMIA; CLINICAL PROTOCOL; CONTROLLED STUDY; COST CONTROL; DISEASE COURSE; DISEASE SEVERITY; FEBRILE NEUTROPENIA; FEMALE; HEMATOLOGIC MALIGNANCY; HOSPITAL ADMISSION; HUMAN; INFECTION; MAJOR CLINICAL STUDY; MALE; MUCOSA INFLAMMATION; MYELOMA; NONHODGKIN LYMPHOMA; OUTPATIENT CARE; PAIN; PATIENT SATISFACTION; PRIORITY JOURNAL; QUALITY OF LIFE; SYMPTOM; TREATMENT OUTCOME; WHOLE BODY RADIATION;

ADULT; COST SAVINGS; FEMALE; FOLLOW-UP STUDIES; HEMATOLOGIC NEOPLASMS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; KAPLAN-MEIERS ESTIMATE; MALE; OUTPATIENTS; PAIN; PATIENT ADMISSION; QUALITY OF LIFE; TRANSPLANTATION, AUTOLOGOUS; WHOLE-BODY IRRADIATION;

EID: 33751049413     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/sj.bmt.1705525     Document Type: Article

References (22)

1. Dix SP, Geller RB. High-dose chemotherapy with autologous stem cell rescue in the outpatient setting. Oncology 2000; 14: 171-185.
2. Gonzalez-Ryan L, Haut PR, Coyne K, Syckle KV, Duerst R, Haro D et al. Developing a pediatric outpatient transplantation program. The Children's Memorial Hospital experience. Front Biosci 2001; 6: 1-5.
3. Corcoran-Buchsel P, Parchem C. Ambulatory care of the bone marrow transplant patient. Semin Oncol Nursing 1988; 4: 41-46.
4. Seropian S, Nadkarni R, Jillella AP, Salloum E, Burtness B, Hu GL et al. Neutropenic infections in 100 patients with non-Hodgkin's lymphoma or Hodgkin's disease treated with highdose BEAM chemotherapy and peripheral blood progenitor cell transplant: Outpatient treatment is a viable option. Bone Marrow Transplant 1999; 23: 599-605.
5. Meisenberg BR, Ferran K, Hollenbach K, Brehm T, Jollon J, Piro LD. Reduced charges and costs associated with outpatient autologous stem cell transplantation. Bone Marrow Transplant 1998; 21: 927-932.
6. Coleman EA, Loon SK, Mattox SG, O'Sullivan P. Symptom management and successful outpatient transplantation for patients with multiple myeloma. Cancer Nurs 2002; 25: 452-460.
7. Ferrara F, Palmieri S, Viola A, Copia C, Schiavone EM, De Simone M et al. Outpatient-based peripheral blood stem cell transplantation for patients with multiple myeloma. Hematol J 2004; 5: 222-225.
8. Jagannath S, Vesole DH, Zhang M, Desikan KR, Copelan N, Jagannath M et al. Feasibility and cost-effectiveness of out-patient transplants in multiple myeloma. Bone Marrow Transplant 1997; 20: 445-450.
9. Grimm PM, Zawacki KL, Mock V, Krumm S, Frink BB. Caregiver responses and needs. An ambulatory bone marrow transplant model. Cancer Practice 2000; 8: 120-128.
10. Stiff PJ, Koester AR, Weidner MK, Dvorak K, Fisher RI. Autologous bone marrow transplantation using unfractionated cells cryopreserved in dimethylsulfoxide and hydroxyethylstarch without controlled-rate freezing. Blood 1987; 70: 974-978.
11. Derogatis LR, Derogatis MF. Pais & PAIS-SR: Administration, Scoring & Procedures Manual-I. Clinical Psychometric Research: Baltimore, MD, 1990.
12. Smilkstein G. The family APGAR: A proposal for a family function test and its use by physicians. J Family Practice 1978; 6: 1231-1239.
13. Montgomery RJV, Gonyea JG, Hooyman NR. Caregiving and the experience of subjective and objective burden. Family Relat 1985; 34: 19-26.
14. Sorror ML, Maris MB, Storb R, Baron F, Sandmaier BM, Maloney DG et al. Hematopoietic cell transplantation (HCT)-specific comorbidity index: A new tool for risk assessment before allogeneic HCT. Blood 2005; 106: 2912-2919.
15. Bredeson C, Perry G, Martens C, McDiarmid S, Bence-Bruckler I, Atkins H et al. Outpatient total body irradiation as a component of a comprehensive outpatient transplant program. Bone Marrow Transplant 2002; 29: 667-671.
16. Dagher R, Robertson KA, Lucas KG, Emmanuel D, Smith FO. Outpatient total body irradiation for pediatric patients undergoing stem cell transplantation. Bone Marrow Transplant 1997; 19: 1065-1067.
17. Hermann RP, Trent M, Cooney J, Cannell PK. Infections in patients managed at home during autologous stem cell transplantation for lymphoma and multiple myeloma. Bone Marrow Transplant 1999; 24: 1213-1217.
18. Westermann AM, Holtkamp MM, Linthorst GA, van Leeuwen L, Willemese EJ, van Dijk WC et al. At home management of aplastic phase following high-dose chemotherapy with stem-cell rescue for hematological and nonhematological malignancies. Ann Oncol 1999; 10: 511-517.
19. Siston AK, List MA, Daugherty CK, Banik DM, Menke C, Cornetta K et al. Psychosocial adjustment of patients and caregivers prior to allogeneic bone marrow transplantation. Bone Marrow Transplant 2001; 27: 1181-1188.
20. Foxall MJ, Gaston-Johansson F. Burden and health outcomes of family caregivers of hospitalized bone marrow transplant patients. J Advanced Nursing 1996; 24: 915-923.
21. Rizzo JD, Vogelsang GB, Krumm S, Frink B, Mock V, Bass EB. Out-patient-based bone marrow transplantation for hematologic malignancies: Cost saving or cost shifting? J Clin Oncol 1999; 17: 2811-2818.
22. Selby GB, Ali LI, Carter TH, Veseley S, Roy V. The influence of health insurance on outcomes of related-donor hematopoietic stem cell transplantation for AML and CML. Biol Blood Marrow Transplant 2001; 7: 576.