Effect of isoquinoline alkaloids of different structural types on antiplatelet aggregation in vitro

Planta Medica

Volumn 72, Issue 13, 2006, Pages 1238-1241

  Chia, Yi Chen ^a   Chang, Fang Rong ^b   Wu, Chin Chung ^b   Teng, Che Ming ^c   Chen, Keh Shaw ^a   Wu, Yang Chang ^b  

^a TAJEN INSTITUTE OF TECHNOLOGY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE; ANTITHROMBOCYTIC AGENT; ARACHIDONIC ACID; COLLAGEN; DISCRETAMINE; ISOQUINOLINE ALKALOID; ISOTETRANDRINE; LINDOLDHAMINE; NORARMEPAVINE; O METHYLARMEPAVINEMETHINE; OCHOTENSIMINE; PAPAVERINE; PROTOPINE; THALICARPINE; THROMBOCYTE ACTIVATING FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG INHIBITION; DRUG ISOLATION; IN VITRO STUDY; NONHUMAN; STRUCTURE ACTIVITY RELATION; THROMBOCYTE AGGREGATION;

ALKALOIDS; ANIMALS; BLOOD PLATELETS; CELLS, CULTURED; ISOQUINOLINES; PLANT EXTRACTS; PLANTS; PLATELET AGGREGATION INHIBITORS; RABBITS;

EID: 33751043645     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-947196     Document Type: Article

References (26)

1. Wu YC, Liou YF, Lu ST, Chen CH, Chang JJ, Lee KH. Cytotoxicity of isoquinoline alkaloids and their N-oxides. Planta Med 1989; 55: 163-5
2. Tzeng CC, Wu YC, Su TL, Watanabe KA, Lu ST, Chou TC. Inhibitory effects of isoquinoline-type alkaloids on leukemic cell growth and macromolecule biosynthesis. Kaohsiung J Med Sci 1990; 6: 58-65
3. Tsai IL, Liou YF, Lu ST. Screening of isoquinoline alkaloids and their derivatives for antibacterial and antifungal activities. Kaohsiung J Med Sci 1989; 5: 132-45
4. Chen KS, Ko FN, Teng CM, Wu YC. Antiplatelet and vasorelaxing actions of some aporphinoids. Planta Med 1996; 62: 133-6
5. Chia YC, Chen KS, Chang YL, Teng CM, Wu YC. Antiplatelet actions of aporphinoids from Formosan plants. Bioorg Med Chem Lett 1999; 9: 3295-300
6. Ukita T, Mizuno D, Tamura T. Studies on the antibacterial properties of berberinium chloride. Jpn J Exp Med 1949; 20: 103-8
7. Awe WU, Gottingen G. Berberine derivatives. VII. Cleavage of 9-benzyl-16,17-dihydrodesoxypalmatine by iodine or mercuric acetate. Arch Pharm 1944; 282: 97-100
8. Yang TH, Lu ST. Studies on the alkaloids of Berberidaceous plants XXVI. Alkaloids of Berberis mingetsensis Hayata. Yakugaku Zasshi 1960; 80: 849-51
9. Sun TT, Loh SH, Kyi ZY. Synthesis of compound related to corydalis B (tetrahydropalmatine). IV. The synthesis of some acyloxy- and alkoxyberbines. Yao Xue Xue Bao 1965; 12: 314-8
10. Richter WJ, Brochmann-Hanssen E. The structure of discretamine, a tetrahydroprotoberberine alkaloid. Helv Chim Acta 1975; 58: 209-11
11. Debska W. Separation and determination of the dissociation constants of chelidonine and protopine by paper chromatography. Nature 1958; 182: 666-7
12. Lu ST, Wang SJ, Su TL. Studies on the alkaloids of Formosan Corydalis species. I. Alkaloids of Corydalis campulicarpa Hayata. Yakugaku Zasshi 1971; 91: 778-81
13. Lu ST, Lan PK. Studies on the alkaloids of Formosa Lauraceous plants. VIII. Alkaloids of Crypyocarya chinensis Hemsl. (1). Structures of the new alkaloids "crychine" and "caryachine". Yakugaku Zasshi 1966; 86: 177-84
14. Lu ST. Studies on the alkaloids of Formosan Lauraceous plants IX. Alkaloids of Cryptocarya chinensis Hemsl and Cryptocarya konishii Hayata. Yakugaku Zasshi 1966; 86: 296-9
15. Lu ST, Su TL, Kametani T, Ihara M. Structural elucidation of two new spirobenzylisoquinoline alkaloids, yenhusomine and yenhusomidine. Heterocycles 1975; 3: 301-5
16. Lu ST, Wu YC, Leou SP. The oxidation of isoquinoline alkaloids with m-chloroperbenzoic acid. J Chin Chem Soc 1987; 34: 33-42
17. Tomita M, Yang TH, Lu ST. Studies on the alkaloids of Formosan Lauraceous plants. I. Alkaloids of Machilus kusanoi Hayata. (1). The isolation of L-(-)-N-norarmepavine. Yakugaku Zasshi 1963; 83: 15-8
18. Lu ST. Studies on the alkaloids of Formosan Lauraceous plants II. Alkaloids of Machilus kusanoi Hayata. (2). The isolation of dl-coclaurine. Yakugaku Zasshi 1963; 83: 19-21
19. Lu ST, Chen IS. Structure of a new bisbenzylisoquinoline alkaloids, m-doldhamine. Heterocycles 1976; 4: 1073-6
20. Tomita M, Furukawa H, Lu ST. The constitution of thalicarpine. Chem Pharm Bull 1967; 15: 959-63
21. Wu YC, Liou YF, Lu ST. Antimicrobial activity of isoquinoline alkaloids and their N-oxide derivatives. Kaohsiung Med Sci 1988; 4: 336-44
22. Yang TH, Lu ST. Studies on the alkaloids of Magnoliaceous plants XXXV. Alkaloids of Magnolia kachirachirai Dandy. (2). The isolation of D-(+)-N-norarmepavine. Yakugaku Zasshi 1963; 83: 22-5
23. Lu ST, Tsai IL. Hofmann elimination with diazomethane on quaternary benzyltetrahydroisoquinoline related alkaloids. Heterocycles 1988; 27: 751-68
24. Lu ST, Su TL, Wang EC. Studies on the alkaloids of Formosan Lauraceous plants XVIII. Alkaloids of Neolitsea buisanensis Yamamato et Kamikoti and Neolitsea aurata (Hay.) Koidz. J Chin Chem Soc 1975; 22: 349-53
25. Lu ST, Wu YC, Leou SP. Alkaloids of Formosan Fissistigma and Goniothalamus species. Phytochemistry 1985; 24: 1829-34
26. Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol 1971; 231: 232-5