Silk sericin-insulin bioconjugates: Synthesis, characterization and biological activity

Journal of Controlled Release

Volumn 115, Issue 3, 2006, Pages 307-315

  Zhang, Yu Qing ^a   Ma, Yan ^a   Xia, Yun Yue ^a   Shen, Wei De ^a   Mao, Jian Ping ^a   Xue, Ren Yu ^a  

^a SOOCHOW UNIVERSITY   (China)

Author keywords

Bioconjugates; Cross linking; Insulin; Silk sericin

Indexed keywords

DEGRADATION; DEGUMMING; INSULIN; SYNTHESIS (CHEMICAL);

CONJUGATES; NATIVE INSULIN; SILK SERICINS;

SILK;

BOVINE SERUM ALBUMIN; GLUTARALDEHYDE; INSULIN; POLYPEPTIDE; SERICIN;

ANTIGENICITY; ARTICLE; BIOLOGICAL ACTIVITY; CROSS LINKING; DRUG CONJUGATION; DRUG HALF LIFE; DRUG SYNTHESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOGENICITY; IN VITRO STUDY; IN VIVO STUDY; INSULIN SYNTHESIS; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SILK;

AMINO ACID SEQUENCE; ANIMALS; BLOOD GLUCOSE; BOMBYX; CHEMISTRY, PHARMACEUTICAL; CROSS-LINKING REAGENTS; DIABETES MELLITUS, EXPERIMENTAL; DRUG STABILITY; GLUTARAL; HYPOGLYCEMIC AGENTS; INSECT PROTEINS; INSULIN; MALE; MICE; MOLECULAR WEIGHT; RABBITS; SERICINS; SERUM ALBUMIN, BOVINE; SILK;

DEGRADATION; SILK; SYNTHESIS;

EID: 33751038123     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.08.019     Document Type: Article

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