Estimating the combined toxicity by two-step prediction model on the complicated chemical mixtures from wastewater treatment plant effluents

Environmental Toxicology and Chemistry

Volumn 25, Issue 8, 2006, Pages 2107-2113

  Ra, Jin Sung ^a   Lee, Byoung Cheun ^a   Chang, Nam Ik ^b   Kim, Sang Don ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

^b Youngsan River Environmental Research Laboratory   (South Korea)

Author keywords

Daphnia magna; Mixture toxicity; Two step predictions; Wastewater treatment plant effluents

Indexed keywords

CONCENTRATION (PROCESS); EFFLUENT TREATMENT; GAS CHROMATOGRAPHY; STATISTICAL METHODS; TOXICITY;

DAPHNIA MAGNA; MIXTURE TOXICITY; TWO-STEP PREDICTIONS; WASTEWATER TREATMENT PLANT EFFLUENTS;

WASTEWATER TREATMENT;

2,4,6 TRICHLOROPHENOL; 4 OCTYLPHENOL; CHOLINESTERASE INHIBITOR; DIMPYLATE; FENOBUCARB; ISOFENPHOS; PENDIMETHALIN; PHTHALIC ACID; PHTHALIC ACID BENZYL BUTYL ESTER; PHTHALIC ACID DIBUTYL ESTER;

CHEMICAL COMPOUND; CRUSTACEAN; EFFLUENT; GAS CHROMATOGRAPHY; INHIBITOR; MASS SPECTROMETRY; PREDICTION; TOXICITY; TOXICITY TEST;

ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DAPHNIA; EFFLUENT TOXICITY; GAS CHROMATOGRAPHY; MASS SPECTROMETRY; MATHEMATICAL MODEL; NONHUMAN; PRIORITY JOURNAL; THEORETICAL MODEL; WASTE WATER MANAGEMENT; WASTE WATER TREATMENT PLANT;

ANIMALS; DAPHNIA; INDUSTRIAL WASTE; MODELS, THEORETICAL; WATER POLLUTANTS, CHEMICAL;

DAPHNIA MAGNA;

EID: 33751027742     PISSN: 07307268     EISSN: None     Source Type: Journal    
DOI: 10.1897/05-484R.1     Document Type: Article

References (29)

1. Cizmas L, McDonald TJ, Phillips TD, Gillespie AM, Lingenfelt er RA, Kubena LF, Phillips TD, Donnelly KC. 2004. Toxicity characterization of complex mixtures using biological and chemical analysis in preparation for assessment of mixture similarity. Environ Sci Technol 38:5127-5133.
2. U.S. Environmental Protection Agency. 1986. Guidelines for the health risk assessment of chemical mixtures; Risk assessment forum. EPA/630/R-98/002. Washington, DC.
3. U.S. Environmental Protection Agency. 2000. Supplementary guidance for conducting health risk assessment of chemical mixtures: Risk assessment forum. EPA/630/R-00/002. Washington, DC.
4. Ren S. 2004. Assessing wastewater toxicity to activated sludge: Recent research and developments. Environ Int 30:1151-1164.
5. Chapman PM. 2000. Whole effluent toxicity testing-Usefulness, level of protection, and risk assessment. Environ Toxicol Chem 19:3-13.
6. Cleuvers M, Altenburger R, Ratte TH. 2002. Combination effect of light and toxicity in algal tests. J Environ Qual 31:539-546.
7. Nissanka R, Delia O, Anderas K. 2001. Defining the impact of weakly estrogenic chemicals on the action of steroidal estrogens. Toxicol Sci 60:296-304.
8. Vighi M, Altenburger R, Arrhenius A, Backhaus T, Bödeker W, Blanck H, Consolaro F, Faust M, Finizio A, Froehner K, Gramatica P, Grimme LH, Grönvall F, Hamer V, Scholze M, Walter H. 2003. Water-quality objectives for mixtures of toxic chemicals: Problems and perspectives. Ecotoxicol Environ Saf 54:139-150.
9. Altenburger R, Schmitt H, Schuurmann G. 2005. Algal toxicity of nitrobenzenes: Combined effect analysis as a pharmacological probe for similar modes of interaction. Environ Toxicol Chem 24:324-333.
10. Drecher K, Boedeker W. 1995. Assessment of the combined effect of substances-The relationship between concentration addition and independent action. Biometrics 51:716-730.
11. Faust M, Altenburger R, Backhaus T, Blanck H, Boedeker W, Gramatica P, Hamer V, Scholze M, Vighi M, Grimme LH. 2001. Predicting the joint algal toxicity of multicomponent s-triazine mixtures at low-effect concentrations of individual toxicants. Aquat Toxicol 56:13-32.
12. Faust M, Altenburger R, Backhaus T, Blanck H, Boedeker W, Gramatica P, Hamer V, Scholze M, Vighi M, Grimme LH. 2003. Joint algal toxicity of 16 dissimilarly acting chemicals is predictable by the concept of independent action. Aquat Toxicol 63:43-63.
13. Backhaus T, Scholze M, Grimme LH. 2000. The single substance and mixture toxicity of quinolones to the bioluminescent bacterium Vibrio fischeri. Aquat Toxicol 49:49-61.
14. Backhaus T. 2004. Toxicity of a mixture of dissimilarly acting substances to natural algal communities: Predictive power and limitations of independent action and concentration addition. Environ Sci Technol 38:6363-6370.
15. Walter H, Consolaro F, Gramatica P, Scholze M, Altenburger R. 2002. Mixture toxicity of priority pollutants at no observed effect concentrations (NOECs). Ecotoxicology 11:299-310.
16. Silva E, Rajapakse N, Kortenkamp A. 2002. Something from "Nothing"-Eight weak estrogenic chemicals combined at concentrations below NOECs produce significant mixture effects. Environ Sci Technol 36:1751-1756.
17. Merino-García D, Kusk KO, Christensen ER. 2003. Joint toxicity of similarly and dissimilarly acting chemicals to Daphnia magna at different response level. Arch Environ Contant Toxicol 45:289-296.
18. Verhaar HJM, Solbé J, Speksnijder J, van Leeuwen CJ, Hermens JLM. 2000. Classifying environmental pollutants: Part 3. External validation of the classification system. Chemosphere 40:875-883.
19. Russom CL, Bradbury SP, Broderius SJ, Hammermeister DE, Drummond RA. 1997. Predicting modes of toxic action from chemical structure: Acute toxicity in the fathead minnow (Pimephales promelas). Environ Toxicol Chem 16:948-967.
20. Altenburger R, Walter H, Grote M. 2004. What contributes to the combined effect of a chemical mixture? Environ Sci Technol 38:6353-6362.
21. Junghans M. 2004. Studies on combination effects of environmentally relevant toxicants. PhD thesis. University of Bremen, Bremen, Germany.
22. Li DH, Park JM, Oh JR. 2001. Silyl derivatization of alkylphenols, chlorophenols, and bisphenol A for simultaneous GC/MS determination. Anal Chem 73:3089-3095.
23. U.S. Environmental Protection Agency. 1993. Methods for measuring the acute toxicity of effluents and receiving waters to freshwater and marine organisms, 4th ed. EPA/600/4-90/027F. Office of Research and Development, Cincinnati, OH.
24. Murk AJ, Legler J, van Lipzig MMH, Meerman JHN, Belfroid AC, Spenkelink A, van der Burg B, Rijs GBJ, Vethaak D. 2002. Detection of estrogenic potency in wastewater and surface water with three in vitro bioassay. Environ Toxicol Chem 21:16-23.
25. Rajapakse N, Silva E, Scholze M, Kortenkamp A. 2004. Deviation from additivity with estrogenic mixtures containing 4-nonylphenol and 4-tert-octylphenol detected in the E-screening assay. Environ Sci Technol 38:6343-6352.
26. Payne J, Rajapakse N, Wilkins M, Kortenkamp A. 2000. Prediction and assessment of the effects of mixtures of four xenoestrogens. Environ Health Perspect 108:983-987.
27. Payne J, Scholze M, Kortenkamp A. 2001. Mixtures of four organochlorines enhance human breast cancer cell proliferation. Environ Health Perspect 109:391-397.
28. Staples CA, Adeams WJ, Parkerton TF, Gorsuch JG, Biddinger GR, Reinert K. 1997. Aquatic toxicity of eighteen phthalate esters. Environ Sci Technol 16:875-891.
29. Bearden AP, Schultz TW. 1997. Structure-activity relationships for Pimephales and Tetrahymena: A mechanism of action approach. Environ Toxicol Chem 16:1311-1317.