99mTc-Sestamibi, A sensitive probe for In Vivo imaging of P-Glycoprotein inhibition by modulators and mdr1 antisense oligodeoxynucleotides

Molecular Imaging and Biology

Volumn 8, Issue 6, 2006, Pages 333-339

  Jekerle, Veronika ^a,b   Wang, Jing Hung ^a   Scollard, Deborah A ^c   Reilly, Raymond M ^a,c   Wiese Michael, M ^b   Piquette Miller, Micheline ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF BONN   (Germany)

^c TORONTO GENERAL HOSPITAL   (Canada)

Author keywords

99mTc sestamibi; Antisense oligodeoxynucleotides; Modulation; Ovarian cancer; P glycoprotein

Indexed keywords

ANTINEOPLASTIC AGENT; ANTISENSE OLIGODEOXYNUCLEOTIDE; ANTISENSE OLIGONUCLEOTIDE; DAUNORUBICIN; GLYCOPROTEIN P; GLYCOPROTEIN P INHIBITOR; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; MULTIDRUG RESISTANCE PROTEIN 1; UNCLASSIFIED DRUG; WK X 34; BENZAMIDE DERIVATIVE; COMPLEMENTARY DNA; RADIOPHARMACEUTICAL AGENT; WK-X-34;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER; CANCER CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; CORRELATION ANALYSIS; DOWN REGULATION; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; FLUORESCENCE MICROSCOPY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMAGE ANALYSIS; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MALE; MODULATION; MOUSE; MOUSE STRAIN; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RADIOISOTOPE DISTRIBUTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY ANALYSIS; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TUMOR CELL; TUMOR XENOGRAFT; ANIMAL; CANCER TRANSPLANTATION; DRUG SCREENING; EVALUATION; GENETICS; METABOLISM; MULTIDRUG RESISTANCE; NUDE MOUSE; OLIGONUCLEOTIDE PROBE; TUMOR CELL LINE;

ANIMALS; BENZAMIDES; CELL LINE, TUMOR; DNA, ANTISENSE; DOWN-REGULATION; DRUG RESISTANCE, MULTIPLE; HUMANS; MALE; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; OLIGONUCLEOTIDE PROBES; P-GLYCOPROTEIN; RADIOPHARMACEUTICALS; TECHNETIUM TC 99M SESTAMIBI; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 33751016632     PISSN: 15361632     EISSN: 18602002     Source Type: Journal    
DOI: 10.1007/s11307-006-0057-0     Document Type: Article

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