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Volumn 107, Issue 10, 2006, Pages 2375-2383

Treatment of patients with metastatic renal cell cancer: A RAND appropriateness panel

Author keywords

Angiogenesis inhibitors; Immunotherapy; Neoplasm metastasis; Nephrectomy; Practice guidelines; Renal cell carcinoma

Indexed keywords

ALPHA INTERFERON; ANGIOGENESIS INHIBITOR; BEVACIZUMAB; GAMMA INTERFERON; INTERLEUKIN 2; SORAFENIB; SUNITINIB; TEMSIROLIMUS; THALIDOMIDE;

EID: 33751010768     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.22260     Document Type: Article
Times cited : (54)

References (54)
  • 3
    • 0042320457 scopus 로고    scopus 로고
    • Cytokine-based therapy for metastatic renal cell cancer
    • Girlitz BJ, Figlin RA. Cytokine-based therapy for metastatic renal cell cancer. Urol Clin North Am. 2003;30:589-600.
    • (2003) Urol Clin North Am , vol.30 , pp. 589-600
    • Girlitz, B.J.1    Figlin, R.A.2
  • 4
    • 0036833980 scopus 로고    scopus 로고
    • Current status of interleukin-2 therapy for metastatic renal cell carcinoma and metastatic melanoma
    • Dutcher J. Current status of interleukin-2 therapy for metastatic renal cell carcinoma and metastatic melanoma. Oncology (Williston Park). 2002;16:4-10.
    • (2002) Oncology (Williston Park) , vol.16 , pp. 4-10
    • Dutcher, J.1
  • 5
    • 0030931682 scopus 로고    scopus 로고
    • Natural history and therapy of metastatic renal cell carcinoma: The role of interleukin-2
    • Bukowski RM. Natural history and therapy of metastatic renal cell carcinoma: the role of interleukin-2. Cancer. 1997;80:1198-1220.
    • (1997) Cancer , vol.80 , pp. 1198-1220
    • Bukowski, R.M.1
  • 6
    • 33644935244 scopus 로고    scopus 로고
    • SU11248 and AG013736: Current data and future trials in renal cell carcinoma
    • Rini BI. SU11248 and AG013736: current data and future trials in renal cell carcinoma. Clin Genitourin Cancer. 2005;4:175-180.
    • (2005) Clin Genitourin Cancer , vol.4 , pp. 175-180
    • Rini, B.I.1
  • 7
    • 33644962673 scopus 로고    scopus 로고
    • Sorafenib: Scientific rationales for single-agent and combination therapy in clear-cell renal cell carcinoma
    • Gollob JA. Sorafenib: scientific rationales for single-agent and combination therapy in clear-cell renal cell carcinoma. Clin Genitourin Cancer. 2005;4:167-174.
    • (2005) Clin Genitourin Cancer , vol.4 , pp. 167-174
    • Gollob, J.A.1
  • 11
    • 9644291700 scopus 로고    scopus 로고
    • The consistency of panelists' appropriateness ratings: Do experts produce clinically logical scores for rectal cancer treatment?
    • Hodgson DC, Brierley JD, Cernat G, et al. The consistency of panelists' appropriateness ratings: do experts produce clinically logical scores for rectal cancer treatment? Health Policy. 2005;71:57-65.
    • (2005) Health Policy , vol.71 , pp. 57-65
    • Hodgson, D.C.1    Brierley, J.D.2    Cernat, G.3
  • 12
    • 0035283198 scopus 로고    scopus 로고
    • Underuse of coronary revascularization procedures in patients considered appropriate candidates for revascularization
    • Hemingway H, Crook AM, Feder G, et al. Underuse of coronary revascularization procedures in patients considered appropriate candidates for revascularization. N Engl J Med. 2001;344:645-654.
    • (2001) N Engl J Med , vol.344 , pp. 645-654
    • Hemingway, H.1    Crook, A.M.2    Feder, G.3
  • 13
    • 0033983628 scopus 로고    scopus 로고
    • Delphi-panel analysis of appropriateness of high-dose chemotherapy and blood cell or bone marrow autotransplants in women with breast cancer
    • Gale RP, Park RE, Dubois R, et al. Delphi-panel analysis of appropriateness of high-dose chemotherapy and blood cell or bone marrow autotransplants in women with breast cancer. Clin Transplant. 2000;14:32-41.
    • (2000) Clin Transplant , vol.14 , pp. 32-41
    • Gale, R.P.1    Park, R.E.2    Dubois, R.3
  • 14
    • 0034849915 scopus 로고    scopus 로고
    • Developing indications for the use of sentinel lymph node biopsy and adjuvant high-dose interferon alfa-2b in melanoma
    • Dubois RW, Swetter SM, Atkins M, et al. Developing indications for the use of sentinel lymph node biopsy and adjuvant high-dose interferon alfa-2b in melanoma. Arch Dermatol. 2001;137:1217-1224.
    • (2001) Arch Dermatol , vol.137 , pp. 1217-1224
    • Dubois, R.W.1    Swetter, S.M.2    Atkins, M.3
  • 15
    • 27244450852 scopus 로고    scopus 로고
    • OncoSurge: A strategy for improving resectability with curative intent in metastatic colorectal cancer
    • Poston GJ, Adam R, Alberts S, et al. OncoSurge: a strategy for improving resectability with curative intent in metastatic colorectal cancer. J Clin Oncol. 2005;23:7125-7134.
    • (2005) J Clin Oncol , vol.23 , pp. 7125-7134
    • Poston, G.J.1    Adam, R.2    Alberts, S.3
  • 16
    • 0032459734 scopus 로고    scopus 로고
    • Delphi-panel analysis of appropriateness of high-dose chemotherapy and blood cell or bone marrow autotransplants in diffuse large-cell lymphoma
    • Gale RP, Park RE, Dubois R, et al. Delphi-panel analysis of appropriateness of high-dose chemotherapy and blood cell or bone marrow autotransplants in diffuse large-cell lymphoma. Leuk Lymphoma. 1998;32:139-149.
    • (1998) Leuk Lymphoma , vol.32 , pp. 139-149
    • Gale, R.P.1    Park, R.E.2    Dubois, R.3
  • 17
    • 0344690184 scopus 로고    scopus 로고
    • Delphi-panel analysis of appropriateness of high-dose therapy and bone marrow transplants in adults with acute myelogenous leukemia in 1st remission
    • Gale RP, Park RE, Dubois RW, et al. Delphi-panel analysis of appropriateness of high-dose therapy and bone marrow transplants in adults with acute myelogenous leukemia in 1st remission. Leuk Res. 1999;23:709-718.
    • (1999) Leuk Res , vol.23 , pp. 709-718
    • Gale, R.P.1    Park, R.E.2    Dubois, R.W.3
  • 18
    • 0032789247 scopus 로고    scopus 로고
    • Delphi-panel analysis of appropriateness of high-dose therapy and bone marrow transplants in chronic myelogenous leukemia in chronic phase
    • Gale RP, Park RE, Dubois RW, et al. Delphi-panel analysis of appropriateness of high-dose therapy and bone marrow transplants in chronic myelogenous leukemia in chronic phase. Leuk Res. 1999;23:817-826.
    • (1999) Leuk Res , vol.23 , pp. 817-826
    • Gale, R.P.1    Park, R.E.2    Dubois, R.W.3
  • 19
    • 0032935505 scopus 로고    scopus 로고
    • Delphi-panel analysis of appropriateness of high-dose therapy and bone marrow autotransplants in newly diagnosed multiple myeloma
    • Gale RP, Park RE, Dubois RW, et al. Delphi-panel analysis of appropriateness of high-dose therapy and bone marrow autotransplants in newly diagnosed multiple myeloma. Leuk Lymphoma. 1999;33:511-519.
    • (1999) Leuk Lymphoma , vol.33 , pp. 511-519
    • Gale, R.P.1    Park, R.E.2    Dubois, R.W.3
  • 20
    • 0032772880 scopus 로고    scopus 로고
    • Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma
    • Motzer RJ, Mazumdar M, Bacik J, Berg W, Amsterdam A, Ferrara J. Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma. J Clin Oncol. 1999;17:2530-2540.
    • (1999) J Clin Oncol , vol.17 , pp. 2530-2540
    • Motzer, R.J.1    Mazumdar, M.2    Bacik, J.3    Berg, W.4    Amsterdam, A.5    Ferrara, J.6
  • 21
    • 0038354576 scopus 로고    scopus 로고
    • Prognostic factors and clinical trials of new agents in patients with metastatic renal cell carcinoma
    • Motzer RJ. Prognostic factors and clinical trials of new agents in patients with metastatic renal cell carcinoma. Crit Rev Oncol Hematol. 2003;46(Suppl):S33-S39.
    • (2003) Crit Rev Oncol Hematol , vol.46
    • Motzer, R.J.1
  • 22
    • 1442290393 scopus 로고    scopus 로고
    • Prognostic factors for survival in previously treated patients with metastatic renal cell carcinoma
    • Motzer RJ, Bacik J, Schwartz LH, et al. Prognostic factors for survival in previously treated patients with metastatic renal cell carcinoma. J Clin Oncol. 2004;22:454-463.
    • (2004) J Clin Oncol , vol.22 , pp. 454-463
    • Motzer, R.J.1    Bacik, J.2    Schwartz, L.H.3
  • 23
    • 0029117871 scopus 로고
    • The use of polyethylene glycol-modified interleukin-2 (PEG-IL-2) in the treatment of patients with metastatic renal cell carcinoma and melanoma. A Phase I study and a randomized prospective study comparing IL-2 alone versus IL-2 combined with PEG-IL-2
    • Yang JC, Topalian SL, Schwartzentruber DJ, et al. The use of polyethylene glycol-modified interleukin-2 (PEG-IL-2) in the treatment of patients with metastatic renal cell carcinoma and melanoma. A Phase I study and a randomized prospective study comparing IL-2 alone versus IL-2 combined with PEG-IL-2. Cancer. 1995;76:687-694.
    • (1995) Cancer , vol.76 , pp. 687-694
    • Yang, J.C.1    Topalian, S.L.2    Schwartzentruber, D.J.3
  • 24
    • 0042914703 scopus 로고    scopus 로고
    • Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer
    • Yang JC, Sherry RM, Steinberg SM, et al. Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer. J Clin Oncol. 2003;21:3127-3132.
    • (2003) J Clin Oncol , vol.21 , pp. 3127-3132
    • Yang, J.C.1    Sherry, R.M.2    Steinberg, S.M.3
  • 25
    • 0041411517 scopus 로고    scopus 로고
    • Adjuvant high-dose bolus interleukin-2 for patients with high-risk renal cell carcinoma: A cytokine working group randomized trial
    • Clark JI, Atkins MB, Urba WJ, et al. Adjuvant high-dose bolus interleukin-2 for patients with high-risk renal cell carcinoma: a cytokine working group randomized trial. J Clin Oncol. 2003;21:3133-3140.
    • (2003) J Clin Oncol , vol.21 , pp. 3133-3140
    • Clark, J.I.1    Atkins, M.B.2    Urba, W.J.3
  • 26
    • 0032784492 scopus 로고    scopus 로고
    • Multicenter, randomized, Phase III trial of CD8(+) tumor-infiltrating lymphocytes in combination with recombinant interleukin-2 in metastatic renal cell carcinoma
    • Figlin RA, Thompson JA, Bukowski RM, et al. Multicenter, randomized, Phase III trial of CD8(+) tumor-infiltrating lymphocytes in combination with recombinant interleukin-2 in metastatic renal cell carcinoma. J Clin Oncol. 1999;17:2521-2529.
    • (1999) J Clin Oncol , vol.17 , pp. 2521-2529
    • Figlin, R.A.1    Thompson, J.A.2    Bukowski, R.M.3
  • 27
    • 0029090362 scopus 로고
    • Phase III randomized trial of interleukin-2 with or without lymphokine-activated killer cells in the treatment of patients with advanced renal cell carcinoma
    • Law TM, Motzer RJ, Mazumdar M, et al. Phase III randomized trial of interleukin-2 with or without lymphokine-activated killer cells in the treatment of patients with advanced renal cell carcinoma. Cancer. 1995;76:824-832.
    • (1995) Cancer , vol.76 , pp. 824-832
    • Law, T.M.1    Motzer, R.J.2    Mazumdar, M.3
  • 28
    • 0033839619 scopus 로고    scopus 로고
    • Expanding the indications for surgery and adjuvant interleukin-2-based immunotherapy in patients with advanced renal cell carcinoma
    • Belldegrun A, Shvarts O, Figlin RA. Expanding the indications for surgery and adjuvant interleukin-2-based immunotherapy in patients with advanced renal cell carcinoma. Cancer J Sci Am. 2000;6(Suppl 1):S88-S92.
    • (2000) Cancer J Sci Am , vol.6 , Issue.SUPPL. 1
    • Belldegrun, A.1    Shvarts, O.2    Figlin, R.A.3
  • 29
    • 2442737061 scopus 로고    scopus 로고
    • Prospective randomized trial of interferon alfa-2a plus vinblastine versus vinblastine alone in patients with advanced renal cell cancer
    • Pyrhonen S, Salminen E, Ruutu M, et al. Prospective randomized trial of interferon alfa-2a plus vinblastine versus vinblastine alone in patients with advanced renal cell cancer. J Clin Oncol. 1999;17:2859-2867.
    • (1999) J Clin Oncol , vol.17 , pp. 2859-2867
    • Pyrhonen, S.1    Salminen, E.2    Ruutu, M.3
  • 30
    • 0033514050 scopus 로고    scopus 로고
    • Interferon-alpha and survival in metastatic renal carcinoma: Early results of a randomised controlled trial
    • Medical Research Council Renal Cancer Collaborators
    • Medical Research Council Renal Cancer Collaborators. Interferon-alpha and survival in metastatic renal carcinoma: early results of a randomised controlled trial. Lancet. 1999;353:14-17.
    • (1999) Lancet , vol.353 , pp. 14-17
  • 31
    • 0033902999 scopus 로고    scopus 로고
    • Phase III trial of interferon alfa-2a with or without 13-cis-retinoic acid for patients with advanced renal cell carcinoma
    • Motzer RJ, Murphy BA, Bacik J, et al. Phase III trial of interferon alfa-2a with or without 13-cis-retinoic acid for patients with advanced renal cell carcinoma. J Clin Oncol. 2000;18:2972-2980.
    • (2000) J Clin Oncol , vol.18 , pp. 2972-2980
    • Motzer, R.J.1    Murphy, B.A.2    Bacik, J.3
  • 32
    • 0035818877 scopus 로고    scopus 로고
    • Nephrectomy followed by interferon alfa-2b compared with interferon alfa-2b alone for metastatic renal-cell cancer
    • Flanigan RC, Salmon SE, Blumenstein BA, et al. Nephrectomy followed by interferon alfa-2b compared with interferon alfa-2b alone for metastatic renal-cell cancer. N Engl J Med. 2001;345:1655-1659.
    • (2001) N Engl J Med , vol.345 , pp. 1655-1659
    • Flanigan, R.C.1    Salmon, S.E.2    Blumenstein, B.A.3
  • 33
    • 0035934596 scopus 로고    scopus 로고
    • Radical nephrectomy plus interferon-alfa-based immunotherapy compared with interferon alfa alone in metastatic renal-cell carcinoma: A randomised trial
    • Mickisch GH, Garin A, van Poppel H, et al. Radical nephrectomy plus interferon-alfa-based immunotherapy compared with interferon alfa alone in metastatic renal-cell carcinoma: a randomised trial. Lancet. 2001;358:966-970.
    • (2001) Lancet , vol.358 , pp. 966-970
    • Mickisch, G.H.1    Garin, A.2    Van Poppel, H.3
  • 34
    • 0029655348 scopus 로고    scopus 로고
    • Interleukin-2 based home therapy of metastatic renal cell carcinoma: Risks and benefits in 215 consecutive single institution patients
    • Lopez Hanninen E, Kirchner H, Atzpodien J. Interleukin-2 based home therapy of metastatic renal cell carcinoma: risks and benefits in 215 consecutive single institution patients. J Urol. 1996;155:19-25.
    • (1996) J Urol , vol.155 , pp. 19-25
    • Lopez Hanninen, E.1    Kirchner, H.2    Atzpodien, J.3
  • 35
    • 7144227930 scopus 로고    scopus 로고
    • Recombinant human interleukin-2, recombinant human interferon alfa-2a, or both in metastatic renal-cell carcinoma
    • Negrier S, Escudier B, Lasset C, et al. Recombinant human interleukin-2, recombinant human interferon alfa-2a, or both in metastatic renal-cell carcinoma. N Engl J Med. 1998;338:1272-1278.
    • (1998) N Engl J Med , vol.338 , pp. 1272-1278
    • Negrier, S.1    Escudier, B.2    Lasset, C.3
  • 36
    • 0031846011 scopus 로고    scopus 로고
    • A randomized Phase II trial of interleukin 2 and interleukin 2-interferon alpha in advanced renal cancer
    • Jayson GC, Middleton M, Lee SM, Ashcroft L, Thatcher N. A randomized Phase II trial of interleukin 2 and interleukin 2-interferon alpha in advanced renal cancer. Br J Cancer. 1998;78:366-369.
    • (1998) Br J Cancer , vol.78 , pp. 366-369
    • Jayson, G.C.1    Middleton, M.2    Lee, S.M.3    Ashcroft, L.4    Thatcher, N.5
  • 37
    • 0031674558 scopus 로고    scopus 로고
    • Interleukin-2, interferon-alpha and interleukin-2 plus interferon-alpha in renal cell carcinoma. A randomized Phase II trial
    • Boccardo F, Rubagotti A, Canobbio L, et al. Interleukin-2, interferon-alpha and interleukin-2 plus interferon-alpha in renal cell carcinoma. A randomized Phase II trial. Tumori. 1998;84:534-539.
    • (1998) Tumori , vol.84 , pp. 534-539
    • Boccardo, F.1    Rubagotti, A.2    Canobbio, L.3
  • 38
    • 0034671326 scopus 로고    scopus 로고
    • Treatment of patients with metastatic renal carcinoma with a combination of subcutaneous interleukin-2 and interferon alfa with or without fluorouracil
    • Negrier S, Caty A, Lesimple T, et al. Treatment of patients with metastatic renal carcinoma with a combination of subcutaneous interleukin-2 and interferon alfa with or without fluorouracil. J Clin Oncol. 2000;18:4009-4015.
    • (2000) J Clin Oncol , vol.18 , pp. 4009-4015
    • Negrier, S.1    Caty, A.2    Lesimple, T.3
  • 39
    • 2142695181 scopus 로고    scopus 로고
    • Interleukin-2- and interferon alfa-2a-based immunochemotherapy in advanced renal cell carcinoma: A Prospectively Randomized Trial of the German Cooperative Renal Carcinoma Chemoimmunotherapy Group (DGCIN)
    • Atzpodien J, Kirchner H, Jonas U, et al. Interleukin-2- and interferon alfa-2a-based immunochemotherapy in advanced renal cell carcinoma: a Prospectively Randomized Trial of the German Cooperative Renal Carcinoma Chemoimmunotherapy Group (DGCIN). J Clin Oncol. 2004;22:1188-1194.
    • (2004) J Clin Oncol , vol.22 , pp. 1188-1194
    • Atzpodien, J.1    Kirchner, H.2    Jonas, U.3
  • 40
    • 16644401873 scopus 로고    scopus 로고
    • Randomized Phase III trial of high-dose interleukin-2 versus subcutaneous interleukin-2 and interferon in patients with metastatic renal cell carcinoma
    • McDermott DF, Regan MM, Clark JI, et al. Randomized Phase III trial of high-dose interleukin-2 versus subcutaneous interleukin-2 and interferon in patients with metastatic renal cell carcinoma. J Clin Oncol. 2005;23:133-141.
    • (2005) J Clin Oncol , vol.23 , pp. 133-141
    • McDermott, D.F.1    Regan, M.M.2    Clark, J.I.3
  • 41
    • 0031879499 scopus 로고    scopus 로고
    • Standard interleukin-2 (IL-2) and interferon-alpha immunotherapy versus an IL-2 and 4-epirubicin immuno-chemotherapeutic association in metastatic renal cell carcinoma
    • Naglieri E, Gebbia V, Durini E, et al. Standard interleukin-2 (IL-2) and interferon-alpha immunotherapy versus an IL-2 and 4-epirubicin immuno-chemotherapeutic association in metastatic renal cell carcinoma. Anticancer Res. 1998;18:2021-2026.
    • (1998) Anticancer Res , vol.18 , pp. 2021-2026
    • Naglieri, E.1    Gebbia, V.2    Durini, E.3
  • 42
    • 0042343801 scopus 로고    scopus 로고
    • A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
    • Yang JC, Haworth L, Sherry RM, et al. A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N Engl J Med. 2003;349:427-434.
    • (2003) N Engl J Med , vol.349 , pp. 427-434
    • Yang, J.C.1    Haworth, L.2    Sherry, R.M.3
  • 43
    • 1542398693 scopus 로고    scopus 로고
    • Randomized Phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma
    • Atkins MB, Hidalgo M, Stadler WM, et al. Randomized Phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma. J Clin Oncol. 2004;22:909-918.
    • (2004) J Clin Oncol , vol.22 , pp. 909-918
    • Atkins, M.B.1    Hidalgo, M.2    Stadler, W.M.3
  • 44
    • 7144255510 scopus 로고    scopus 로고
    • Interferon gamma-1b compared with placebo in metastatic renal-cell carcinoma
    • Gleave ME, Elhilali M, Fradet Y, et al. Interferon gamma-1b compared with placebo in metastatic renal-cell carcinoma. N Engl J Med. 1998;338:1265-1271.
    • (1998) N Engl J Med , vol.338 , pp. 1265-1271
    • Gleave, M.E.1    Elhilali, M.2    Fradet, Y.3
  • 45
    • 0038016523 scopus 로고    scopus 로고
    • Thalidomide therapy for renal cell carcinoma
    • Amato RJ. Thalidomide therapy for renal cell carcinoma. Crit Rev Oncol Hematol. 2003;46(Suppl):S59-S65.
    • (2003) Crit Rev Oncol Hematol , vol.46 , Issue.SUPPL.
    • Amato, R.J.1
  • 46
    • 9744226669 scopus 로고    scopus 로고
    • SUO11248, a novel tyrosine kinase inhibitor, shows antitumor activity in second-line therapy for patients with metastatic renal cell carcinoma: Results of a Phase 2 trial
    • Abstract
    • Motzer RJ, Rini BI, Michaelson MD, et al. SUO11248, a novel tyrosine kinase inhibitor, shows antitumor activity in second-line therapy for patients with metastatic renal cell carcinoma: results of a Phase 2 trial. J Clin Oncol (Meeting Abstracts). 2004;22:4500. Abstract.
    • (2004) J Clin Oncol (Meeting Abstracts) , vol.22 , pp. 4500
    • Motzer, R.J.1    Rini, B.I.2    Michaelson, M.D.3
  • 47
    • 4644276593 scopus 로고    scopus 로고
    • Preliminary antitumor activity of BAY 43-9006 in metastatic renal cell carcinoma and other advanced refractory solid tumors in a Phase II randomized discontinuation trial (RDT)
    • Abstract
    • Ratain MJ, Flaherty KT, Stadler WM, et al. Preliminary antitumor activity of BAY 43-9006 in metastatic renal cell carcinoma and other advanced refractory solid tumors in a Phase II randomized discontinuation trial (RDT). J Clin Oncol. 2004;22:4501. Abstract.
    • (2004) J Clin Oncol , vol.22 , pp. 4501
    • Ratain, M.J.1    Flaherty, K.T.2    Stadler, W.M.3
  • 48
    • 23844480013 scopus 로고    scopus 로고
    • Phase 2 trials of SU11248 show antitumor activity in second-line therapy for patients with metastatic renal cell carcinoma (RCC)
    • Abstract
    • Motzer RJ, Rini BI, Michaelson MD, et al. Phase 2 trials of SU11248 show antitumor activity in second-line therapy for patients with metastatic renal cell carcinoma (RCC). J Clin Oncol (MeetingAbstracts). 2005;23:4508. Abstract.
    • (2005) J Clin Oncol (MeetingAbstracts) , vol.23 , pp. 4508
    • Motzer, R.J.1    Rini, B.I.2    Michaelson, M.D.3
  • 49
    • 23844558595 scopus 로고    scopus 로고
    • Randomized Phase III trial of the Raf kinase and VEGFR inhibitor sorafenib (BAY 43-9006) in patients with advanced renal cell carcinoma (RCC)
    • Abstract
    • Escudier B, Szczylik C, Eisen T, et al. Randomized Phase III trial of the Raf kinase and VEGFR inhibitor sorafenib (BAY 43-9006) in patients with advanced renal cell carcinoma (RCC). J Clin Oncol (Meeting Abstracts). 2005;23:LBA4510. Abstract.
    • (2005) J Clin Oncol (Meeting Abstracts) , vol.23
    • Escudier, B.1    Szczylik, C.2    Eisen, T.3
  • 50
    • 23844455555 scopus 로고    scopus 로고
    • Final findings from a Phase II, placebo-controlled randomized discontinuation trial (RDT) of sorafenib (BAY 43-9006) in patients with advanced renal cell carcinoma (RCC)
    • Abstract
    • Ratain MJ, Eisen T, Stadler WM, et al. Final findings from a Phase II, placebo-controlled randomized discontinuation trial (RDT) of sorafenib (BAY 43-9006) in patients with advanced renal cell carcinoma (RCC). J Clin Oncol (Meeting Abstracts). 2005;23:4544. Abstract.
    • (2005) J Clin Oncol (Meeting Abstracts) , vol.23 , pp. 4544
    • Ratain, M.J.1    Eisen, T.2    Stadler, W.M.3
  • 51
    • 33646571274 scopus 로고    scopus 로고
    • Do cytokines improve survival in patients with metastatic renal cell carcinoma (MRCC) of intermediate prognosis? Results of the prospective randomized PERCY Quattro trial
    • Abstract
    • Negrier S, Perol D, Ravaud A, et al. Do cytokines improve survival in patients with metastatic renal cell carcinoma (MRCC) of intermediate prognosis? Results of the prospective randomized PERCY Quattro trial. J Clin Oncol (Meeting Abstracts). 2005;23:LBA4511. Abstract.
    • (2005) J Clin Oncol (Meeting Abstracts) , vol.23
    • Negrier, S.1    Perol, D.2    Ravaud, A.3
  • 52
    • 33748590610 scopus 로고    scopus 로고
    • Phase III randomized trial of sunitinib malate (SU11248) versus interferon-alfa (IFN-α) as first-line systemic therapy for patients with metastatic renal cell carcinoma (mRCC)
    • Abstract
    • Motzer RJ, Hutson TE, Tomczak P, et al. Phase III randomized trial of sunitinib malate (SU11248) versus interferon-alfa (IFN-α) as first-line systemic therapy for patients with metastatic renal cell carcinoma (mRCC). J Clin Oncol (Meeting Abstracts). 2006;18S:LBA3. Abstract.
    • (2006) J Clin Oncol (Meeting Abstracts) , vol.18
    • Motzer, R.J.1    Hutson, T.E.2    Tomczak, P.3
  • 53
    • 33748363166 scopus 로고    scopus 로고
    • A Phase 3, randomized, 3-arm study of temsirolimus (TEMSR) or interferon-alpha (IFN) or the combination of TEMSR + IFN in the treatment of first-line, poor-risk patients with advanced renal cell carcinoma (adv RCC)
    • Abstract
    • Hudes G, Carducci M, Tomczak P, et al. A Phase 3, randomized, 3-arm study of temsirolimus (TEMSR) or interferon-alpha (IFN) or the combination of TEMSR + IFN in the treatment of first-line, poor-risk patients with advanced renal cell carcinoma (adv RCC). J Clin Oncol (Meeting Abstracts). 2006;18S:LBA4. Abstract.
    • (2006) J Clin Oncol (Meeting Abstracts) , vol.18
    • Hudes, G.1    Carducci, M.2    Tomczak, P.3
  • 54
    • 0034852781 scopus 로고    scopus 로고
    • Guidelines for the safe administration of high-dose interleukin-2
    • Schwartzentruber DJ. Guidelines for the safe administration of high-dose interleukin-2. J Immunol 2001;24:287-293.
    • (2001) J Immunol , vol.24 , pp. 287-293
    • Schwartzentruber, D.J.1


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