L-DOPA inhibits depolarization-induced [3H]GABA release in the dopamine-denervated globus pallidus of the rat: The effect is dopamine independent and mediated by D2-like receptors

Journal of Neural Transmission

Volumn 113, Issue 12, 2006, Pages 1847-1853

  Silva, I ^a   Cortes, H ^a   Escartin E ^c   Rangel, C ^a   Floran L ^a   Erlij, D ^b   Aceves, J ^a   Floran B ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

^b NEW YORK UNIVERSITY   (United States)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

AADC; Dopamine receptors; GABA release; L DOPA effects; NSD 1015; Parkinson disease; Presynaptic D2 receptors

Indexed keywords

3 HYDROXYBENZYLHYDRAZINE; 4 AMINOBUTYRIC ACID; DOPA DECARBOXYLASE INHIBITOR; DOPAMINE; DOPAMINE 2 RECEPTOR; LEVODOPA METHYL ESTER;

4 AMINOBUTYRIC ACID RELEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN DAMAGE; CONTROLLED STUDY; DENERVATION; DEPOLARIZATION; DOPAMINE BRAIN LEVEL; DOPAMINE RELEASE; DRUG MECHANISM; DRUG RECEPTOR BINDING; EXTRAPYRAMIDAL SYNDROME; GLOBUS PALLIDUS; IC 50; MALE; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT;

ANIMALS; DATA INTERPRETATION, STATISTICAL; DECARBOXYLATION; DENERVATION; DOPA DECARBOXYLASE; DOPAMINE; DOPAMINE AGENTS; DOPAMINE ANTAGONISTS; ENZYME INHIBITORS; GAMMA-AMINOBUTYRIC ACID; GLOBUS PALLIDUS; HYDRAZINES; LEVODOPA; MALE; MEDIAL FOREBRAIN BUNDLE; OXIDOPAMINE; POTASSIUM; RATS; RATS, WISTAR; RECEPTORS, DOPAMINE D2; STEREOTYPED BEHAVIOR; SULPIRIDE; SYMPATHECTOMY, CHEMICAL; SYMPATHOLYTICS;

EID: 33750997314     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-006-0493-7     Document Type: Article

References (28)

1. J Aceves AC Cuello 1981 Dopamine release induced by electrical stimulation of microdissected caudate-putamen and substantia nigra of the rat brain Neuroscience 6 2069 2075
2. J Aceves B Floran D Martinez-Fong A Sierra S Hernandez S Mariscal 1991 L-dopa stimulates the release of [3H]gamma-aminobutyric acid in the basal ganglia of 6-hydroxydopamine lesioned rats Neurosci Lett 121 223 226
3. R Arai N Karasawa M Geffard T Nagatsu I Nagatsu 1994 Immunohistochemical evidence that central serotonin neurons produce dopamine from exogenous L-DOPA in the rat, with reference to the involvement of aromatic L-amino acid decarboxylase Brain Res 667 295 299
4. D Bengel O Johren AM Andrews A Heils R Mossner GL Sanvitto JM Saavedra KP Lesch DL Murphy 1997 Cellular localization and expression of the serotonin transporter in mouse brain Brain Res 778 338 345
5. AJ Cooper IM Stanford 2001 Dopamine D2 receptor mediated presynaptic inhibition of striatopallidal GABA (A) IPSCs in vitro Neuropharmacology 41 62 71
6. MR DeLong 1990 Primate models of movement disorders of basal ganglia origin Trends Neurosci 13 281 285
7. A Fisher CS Biggs O Eradiri MS Starr 2000 Dual effects of L-3, 4-dihydroxyphenylalanine on aromatic L-amino acid decarboxylase, dopamine release and motor stimulation in the reserpine-treated rat: evidence that behaviour is dopamine independent Neuroscience 95 97 111
8. B Floran J Aceves A Sierra D Martinez-Fong 1990 Activation of D1 dopamine receptors stimulates the release of GABA in the basal ganglia of the rat Neurosci Lett 116 136 140
9. B Floran C Barajas L Floran D Erlij J Aceves 2002 Adenosine A1 receptors control dopamine D1-dependent (3)H-GABA release in slices of substantia nigra pars reticulata and motor behavior in the rat Neuroscience 115 743 751
10. B Floran L Floran A Sierra J Aceves 1997 D2 receptor-mediated inhibition of GABA release by endogenous dopamine in the rat globus pallidus Neurosci Lett 237 1 4
11. B Floran I Silva C Nava J Aceves 1988 Presynaptic modulation of the release of GABA by GABAA receptors in pars compacta and by GABAB receptors in pars reticulata of the rat substantia nigra Eur J Pharmacol 150 277 286
12. AL Frankhuyzen AH Mulder 1982 A cumulative dose-response technique for the characterization of presynaptic receptors modulating Eur J Pharmacol 78 91 97
13. A Galvan B Floran D Erlij J Aceves 2001 Intrapallidal dopamine restores motor deficits induced by 6-hydroxydopamine in the rat J Neural Transm 108 153 166
14. JL Gongora A Sierra S Mariscal J Aceves 1988 Physostigmine stimulates phosphoinositide breakdown in the rat neostriatum Eur J Pharmacol 155 49 55
15. JL Hudson CG van Horne I Stromberg S Brock J Clayton J Masserano BJ Hoffer GA Gerhardt 1993 Correlation of apomorphine- and amphetamine-induced turning with nigrostriatal dopamine content in unilateral 6-hydroxydopamine lesioned rats Brain Res 626 167 174
16. A Lopez A Munoz MJ Guerra JL Labandeira-Garcia 2001 Mechanisms of the effects of exogenous levodopa on the dopamine- denervated striatum Neuroscience 103 639 651
17. Y Misu Y Goshima T Kubo 1986 Biphasic actions of L-DOPA on the release of endogenous dopamine via presynaptic receptors in rat striatal slices Neurosci Lett 72 194 198
18. Y Misu Y Goshima T Miyamae 2002 Is DOPA a neurotransmitter? TIPS 23 262 268
19. S Nakamura JL Yue Y Goshima T Miyamae H Ueda Y Misu 1994 Non-effective dose of exogenously applied L-dopa itself stereoselectively potentiates postsynaptic D2 receptor-mediated locomotor activities of conscious rats Neurosci Lett 170 22 26
20. T Nakazato A Akiyama 2002 Behavioral activity and stereotypy in rats induced by L-DOPA metabolites: a possible role in the adverse effects of chronic L-DOPA treatment of Parkinson's disease Brain Res 930 134 142
21. T Nakazato A Akiyama 1989 Effect of exogenous L-dopa on behavior in the rat: an in vivo voltammetric study Brain Res 490 332 338
22. J Opacka-Juffry S Ashworth RG Ahier SP Hume 1998 Modulatory effects of L-DOPA on D2 dopamine receptors in rat striatum, measured using in vivo microdialysis and PET J Neural Transm 105 349 364
23. E Querejeta A Delgado R Valdiosera D Erlij J Aceves 2001 Intrapallidal D2 dopamine receptors control globus pallidus neuron activity in the rat Neurosci Lett 300 79 82
24. MG Rosales D Martinez-Fong R Morales A Nunez G Flores JL Gongora-Alfaro B Floran J Aceves 1997 Reciprocal interaction between glutamate and dopamine in the pars reticulata of the rat substantia nigra: a microdialysis study Neuroscience 80 803 810
25. Y Takeuchi T Sawada S Blunt P Jenner CD Marsden 1991 Effects of 6-hydroxydopamine lesions of the nigrostriatal pathway on striatal serotonin innervation in adult rats Brain Res 562 301 305
26. H Tanaka K Kannari T Maeda M Tomiyama T Suda M Matsunaga 1999 Role of serotonergic neurons in L-DOPA-derived extracellular dopamine in the striatum of 6-OHDA-lesioned rats Neuroreport 10 631 634
27. SA Treseder S Rose L Summo P Jenner 2003 Commonly used L-amino acid decarboxylase inhibitors block monoamine oxidase activity in the rat J Neural Transm 110 229 238
28. JL Yue S Nakamura H Ueda Y Misu 1994 Endogenously released L-dopa itself tonically functions to potentiate postsynaptic D2 receptor-mediated locomotor activities of conscious rats Neurosci Lett 170 107 110