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Volumn 42, Issue 16, 2006, Pages 2815-2820

Expression of p16INK4a in relation to histopathology and viral load of 'high-risk' HPV types in cervical neoplastic lesions

Author keywords

Cervical neoplastic lesions; Human papillomavirus; p16INK4a; Viral load

Indexed keywords

PROTEIN P16INK4A;

EID: 33750992174     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2006.06.023     Document Type: Article
Times cited : (11)

References (31)
  • 1
    • 0036221471 scopus 로고    scopus 로고
    • The causal relation between human papillomavirus and cervical cancer
    • Bosch F.X., Lorinca A., Munoz N., Meijer C.J., and Shah K.V. The causal relation between human papillomavirus and cervical cancer. J Clin Pathol 55 (2002) 244-265
    • (2002) J Clin Pathol , vol.55 , pp. 244-265
    • Bosch, F.X.1    Lorinca, A.2    Munoz, N.3    Meijer, C.J.4    Shah, K.V.5
  • 2
    • 0032840918 scopus 로고    scopus 로고
    • Human papillomavirus is a necessary cause of invasive cervical cancer worldwide
    • Walboomers J.M., Jacobs M.V., Manos M.M., et al. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol 189 1 (1999) 12-19
    • (1999) J Pathol , vol.189 , Issue.1 , pp. 12-19
    • Walboomers, J.M.1    Jacobs, M.V.2    Manos, M.M.3
  • 3
    • 0027215213 scopus 로고
    • Epidemiologic evidence showing that human papillomavirus infection causes most cervical intraepithelial neoplasia
    • Schiffman M.H., Bauer H.M., Hoover R.N., et al. Epidemiologic evidence showing that human papillomavirus infection causes most cervical intraepithelial neoplasia. J Natl Cancer Inst 85 12 (1993) 958-964
    • (1993) J Natl Cancer Inst , vol.85 , Issue.12 , pp. 958-964
    • Schiffman, M.H.1    Bauer, H.M.2    Hoover, R.N.3
  • 4
    • 13944260766 scopus 로고    scopus 로고
    • Development and duration of human papillomavirus lesions, after initial infection
    • Winer R.L., Kiviat N., Hughes J.P., et al. Development and duration of human papillomavirus lesions, after initial infection. J Infect Dis 191 5 (2005) 731-738
    • (2005) J Infect Dis , vol.191 , Issue.5 , pp. 731-738
    • Winer, R.L.1    Kiviat, N.2    Hughes, J.P.3
  • 5
    • 0033519946 scopus 로고    scopus 로고
    • Relation of human papillomavirus status to cervical lesions and consequences for cervical-cancer screening: a prospective study
    • Nobbenhuis M.A., Walboomers J.M., Helmerhorst T.J., et al. Relation of human papillomavirus status to cervical lesions and consequences for cervical-cancer screening: a prospective study. Lancet 354 9172 (1999) 20-25
    • (1999) Lancet , vol.354 , Issue.9172 , pp. 20-25
    • Nobbenhuis, M.A.1    Walboomers, J.M.2    Helmerhorst, T.J.3
  • 6
    • 0037421589 scopus 로고    scopus 로고
    • Epidemiologic classification of human papillomavirus types associated with cervical cancer
    • Munoz N., Bosch F.X., de Sanjose S., et al. Epidemiologic classification of human papillomavirus types associated with cervical cancer. N Engl J Med 348 6 (2003) 518-527
    • (2003) N Engl J Med , vol.348 , Issue.6 , pp. 518-527
    • Munoz, N.1    Bosch, F.X.2    de Sanjose, S.3
  • 7
    • 0028181889 scopus 로고
    • Invasive cancer of the cervix in women with mild dyskaryosis followed up cytologically
    • Soutter W.P., and Fletcher A. Invasive cancer of the cervix in women with mild dyskaryosis followed up cytologically. BMJ 308 6941 (1994) 1421-1423
    • (1994) BMJ , vol.308 , Issue.6941 , pp. 1421-1423
    • Soutter, W.P.1    Fletcher, A.2
  • 8
    • 0034709683 scopus 로고    scopus 로고
    • Viral load of human papilloma virus 16 as a determinant for development of cervical carcinoma in situ: a nested case-control study
    • Josefsson A.M., Magnusson P.K., Ylitalo N., et al. Viral load of human papilloma virus 16 as a determinant for development of cervical carcinoma in situ: a nested case-control study. Lancet 355 9222 (2000) 2189-2192
    • (2000) Lancet , vol.355 , Issue.9222 , pp. 2189-2192
    • Josefsson, A.M.1    Magnusson, P.K.2    Ylitalo, N.3
  • 9
    • 16244375196 scopus 로고    scopus 로고
    • High viral loads of human papillomavirus predict risk of invasive cervical carcinoma
    • Moberg M., Gustavsson I., Wilander E., and Gyllensten U. High viral loads of human papillomavirus predict risk of invasive cervical carcinoma. Br J Cancer 92 5 (2005) 891-894
    • (2005) Br J Cancer , vol.92 , Issue.5 , pp. 891-894
    • Moberg, M.1    Gustavsson, I.2    Wilander, E.3    Gyllensten, U.4
  • 10
    • 22044437091 scopus 로고    scopus 로고
    • Type distribution, viral load and integration status of high-risk human papillomaviruses in pre-stages of cervical cancer (CIN)
    • Andersson S., Safari H., Mints M., Lewensohn-Fuchs I., Gyllensten U., and Johansson B. Type distribution, viral load and integration status of high-risk human papillomaviruses in pre-stages of cervical cancer (CIN). Br J Cancer 92 12 (2005) 2195-2200
    • (2005) Br J Cancer , vol.92 , Issue.12 , pp. 2195-2200
    • Andersson, S.1    Safari, H.2    Mints, M.3    Lewensohn-Fuchs, I.4    Gyllensten, U.5    Johansson, B.6
  • 11
    • 17844387136 scopus 로고    scopus 로고
    • p16(INK4a) as a complementary marker of high-grade intraepithelial lesions of the uterine cervix. I: Experience with squamous lesions in 189 consecutive cervical biopsies
    • Dray M., Russell P., Dalrymple C., et al. p16(INK4a) as a complementary marker of high-grade intraepithelial lesions of the uterine cervix. I: Experience with squamous lesions in 189 consecutive cervical biopsies. Pathology 37 2 (2005) 112-124
    • (2005) Pathology , vol.37 , Issue.2 , pp. 112-124
    • Dray, M.1    Russell, P.2    Dalrymple, C.3
  • 12
    • 0029975913 scopus 로고
    • Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity
    • Khleif S.N., DeGregori J., Yee C.L., et al. Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity. Proc Natl Acad Sci 93 9 (1995) 4350-4354
    • (1995) Proc Natl Acad Sci , vol.93 , Issue.9 , pp. 4350-4354
    • Khleif, S.N.1    DeGregori, J.2    Yee, C.L.3
  • 13
    • 0141705411 scopus 로고    scopus 로고
    • P16 overexpression and human papillomavirus infection in small cell carcinoma of the uterine cervix
    • Masumoto N., Fujii T., Ishikawa M., et al. P16 overexpression and human papillomavirus infection in small cell carcinoma of the uterine cervix. Hum Pathol 34 8 (2003) 778-783
    • (2003) Hum Pathol , vol.34 , Issue.8 , pp. 778-783
    • Masumoto, N.1    Fujii, T.2    Ishikawa, M.3
  • 14
    • 0031740497 scopus 로고    scopus 로고
    • Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions
    • Sano T., Oyama T., Kashiwabara K., Fukuda T., and Nakajima T. Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions. Am J Pathol 153 (1998) 1741-1748
    • (1998) Am J Pathol , vol.153 , pp. 1741-1748
    • Sano, T.1    Oyama, T.2    Kashiwabara, K.3    Fukuda, T.4    Nakajima, T.5
  • 15
    • 0035871985 scopus 로고    scopus 로고
    • Overexpression of p16(INK4A) as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri
    • Klaes R., Friedrich T., Spitkovsky D., et al. Overexpression of p16(INK4A) as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri. Int J Cancer 92 2 (2001) 276-284
    • (2001) Int J Cancer , vol.92 , Issue.2 , pp. 276-284
    • Klaes, R.1    Friedrich, T.2    Spitkovsky, D.3
  • 16
    • 0036850358 scopus 로고    scopus 로고
    • New markers for cervical dysplasia to visualise the genomic chaos created by aberrant oncogenic papillomavirus infections
    • von Knebel Doeberitz M. New markers for cervical dysplasia to visualise the genomic chaos created by aberrant oncogenic papillomavirus infections. Eur J Cancer 38 17 (2002) 2229-2242
    • (2002) Eur J Cancer , vol.38 , Issue.17 , pp. 2229-2242
    • von Knebel Doeberitz, M.1
  • 17
    • 12144251609 scopus 로고    scopus 로고
    • p16INK4A positivity in benign, premalignant and malignant cervical glandular lesions: a potential diagnostic problem
    • Murphy N., Heffron C.C., King B., et al. p16INK4A positivity in benign, premalignant and malignant cervical glandular lesions: a potential diagnostic problem. Virchows Arch 445 6 (2004) 610-615
    • (2004) Virchows Arch , vol.445 , Issue.6 , pp. 610-615
    • Murphy, N.1    Heffron, C.C.2    King, B.3
  • 18
    • 20844443130 scopus 로고    scopus 로고
    • p16INK4A, CDC6, and MCM5: predictive biomarkers in cervical preinvasive neoplasia and cervical cancer
    • Murphy N., Ring M., Heffron C.C., et al. p16INK4A, CDC6, and MCM5: predictive biomarkers in cervical preinvasive neoplasia and cervical cancer. J Clin Pathol 58 5 (2005) 525-534
    • (2005) J Clin Pathol , vol.58 , Issue.5 , pp. 525-534
    • Murphy, N.1    Ring, M.2    Heffron, C.C.3
  • 19
    • 1842583607 scopus 로고    scopus 로고
    • Predictive significance of the alterations of p16INK4A, p14ARF, p53, and proliferating cell nuclear antigen expression in the progression of cervical cancer
    • Wang J.L., Zheng B.Y., Li X.D., Angstrom T., Lindstrom M.S., and Wallin K.L. Predictive significance of the alterations of p16INK4A, p14ARF, p53, and proliferating cell nuclear antigen expression in the progression of cervical cancer. Clin Cancer Res 10 7 (2004) 2407-2414
    • (2004) Clin Cancer Res , vol.10 , Issue.7 , pp. 2407-2414
    • Wang, J.L.1    Zheng, B.Y.2    Li, X.D.3    Angstrom, T.4    Lindstrom, M.S.5    Wallin, K.L.6
  • 20
    • 0344990170 scopus 로고    scopus 로고
    • Expression of p16 protein identifies a distinct entity of tonsillar carcinomas associated with human papillomavirus
    • Klussmann J.P., Gultekin E., Weissenborn S.J., et al. Expression of p16 protein identifies a distinct entity of tonsillar carcinomas associated with human papillomavirus. Am J Pathol 162 3 (2003) 747-753
    • (2003) Am J Pathol , vol.162 , Issue.3 , pp. 747-753
    • Klussmann, J.P.1    Gultekin, E.2    Weissenborn, S.J.3
  • 21
    • 0036895918 scopus 로고    scopus 로고
    • Overexpression of p16INK4A in liquid-based specimens (SurePath) as marker of cervical dysplasia and neoplasia
    • Saqi A., Pasha T.L., McGrath C.M., Yu G.H., Zhang P., and Gupta P. Overexpression of p16INK4A in liquid-based specimens (SurePath) as marker of cervical dysplasia and neoplasia. Diagn Cytopathol 27 6 (2002) 365-370
    • (2002) Diagn Cytopathol , vol.27 , Issue.6 , pp. 365-370
    • Saqi, A.1    Pasha, T.L.2    McGrath, C.M.3    Yu, G.H.4    Zhang, P.5    Gupta, P.6
  • 22
    • 0036826860 scopus 로고    scopus 로고
    • p16INK4a immunohistochemistry improves interobserver agreement in the diagnosis of cervical intraepithelial neoplasia
    • Klaes R., Benner A., Friedrich T., et al. p16INK4a immunohistochemistry improves interobserver agreement in the diagnosis of cervical intraepithelial neoplasia. Am J Surg Pathol 26 11 (2002) 1389-1399
    • (2002) Am J Surg Pathol , vol.26 , Issue.11 , pp. 1389-1399
    • Klaes, R.1    Benner, A.2    Friedrich, T.3
  • 23
    • 0032589106 scopus 로고    scopus 로고
    • Immunohistochemical survey of p16INK4A expression in normal human adult and infant tissues
    • Nielsen G.P., Stemmer-Rachamimov A.O., Shaw J., Roy J.E., Koh J., and Louis D.N. Immunohistochemical survey of p16INK4A expression in normal human adult and infant tissues. Lab Invest 79 9 (1999) 1137-1143
    • (1999) Lab Invest , vol.79 , Issue.9 , pp. 1137-1143
    • Nielsen, G.P.1    Stemmer-Rachamimov, A.O.2    Shaw, J.3    Roy, J.E.4    Koh, J.5    Louis, D.N.6
  • 24
    • 0042261942 scopus 로고    scopus 로고
    • Ki-67 immunocytochemistry in liquid based cervical cytology: useful as an adjunctive tool?
    • Sahebali S., Depuydt C.E., Segers K., Vereecken A.J., Van Marck E., and Bogers J.J. Ki-67 immunocytochemistry in liquid based cervical cytology: useful as an adjunctive tool?. J Clin Pathol 56 9 (2003) 681-686
    • (2003) J Clin Pathol , vol.56 , Issue.9 , pp. 681-686
    • Sahebali, S.1    Depuydt, C.E.2    Segers, K.3    Vereecken, A.J.4    Van Marck, E.5    Bogers, J.J.6
  • 25
    • 0037385666 scopus 로고    scopus 로고
    • Low- and high-risk CIN 1 and 2 lesions: prospective predictive value of grade, HPV, and Ki-67 immuno-quantitative variables
    • Kruse A.J., Baak J.P., Janssen E.A., et al. Low- and high-risk CIN 1 and 2 lesions: prospective predictive value of grade, HPV, and Ki-67 immuno-quantitative variables. J Pathol 199 4 (2003) 462-470
    • (2003) J Pathol , vol.199 , Issue.4 , pp. 462-470
    • Kruse, A.J.1    Baak, J.P.2    Janssen, E.A.3
  • 26
    • 26644461201 scopus 로고    scopus 로고
    • Cell cycle and/or proliferation markers: what is the best method to discriminate cervical high-grade lesions?
    • Lorenzato M., Caudroy S., Bronner C., et al. Cell cycle and/or proliferation markers: what is the best method to discriminate cervical high-grade lesions?. Hum Pathol 36 10 (2005) 1101-1107
    • (2005) Hum Pathol , vol.36 , Issue.10 , pp. 1101-1107
    • Lorenzato, M.1    Caudroy, S.2    Bronner, C.3
  • 27
    • 0036411845 scopus 로고    scopus 로고
    • Immunohistochemical staining with MIB1, bcl2 and p16 assists in the distinction of cervical glandular intraepithelial neoplasia from tubo-endometrial metaplasia, endometriosis and microglandular hyperplasia
    • Cameron R.I., Maxwell P., Jenkins D., and McCluggage W.G. Immunohistochemical staining with MIB1, bcl2 and p16 assists in the distinction of cervical glandular intraepithelial neoplasia from tubo-endometrial metaplasia, endometriosis and microglandular hyperplasia. Histopathology 41 4 (2002) 313-321
    • (2002) Histopathology , vol.41 , Issue.4 , pp. 313-321
    • Cameron, R.I.1    Maxwell, P.2    Jenkins, D.3    McCluggage, W.G.4
  • 28
    • 33244466951 scopus 로고    scopus 로고
    • Immunohistochemical expression of p16 (INK4a) is predictive of HR-HPV infection in cevical low-grade lesions
    • Benevolo M., Mottolese M., Marandino F., Vocaturo G., Sindico R., and Piperno G. Immunohistochemical expression of p16 (INK4a) is predictive of HR-HPV infection in cevical low-grade lesions. Mod Pathol 19 3 (2006) 384-391
    • (2006) Mod Pathol , vol.19 , Issue.3 , pp. 384-391
    • Benevolo, M.1    Mottolese, M.2    Marandino, F.3    Vocaturo, G.4    Sindico, R.5    Piperno, G.6
  • 29
    • 0029041842 scopus 로고
    • Prevalence of human papillomavirus in cervical cancer: a worldwide perspective. International biological study on cervical cancer (IBSCC) Study Group
    • Bosch F.X., Manos M.M., Munoz N., et al. Prevalence of human papillomavirus in cervical cancer: a worldwide perspective. International biological study on cervical cancer (IBSCC) Study Group. J Natl Cancer Inst 87 11 (1995) 796-802
    • (1995) J Natl Cancer Inst , vol.87 , Issue.11 , pp. 796-802
    • Bosch, F.X.1    Manos, M.M.2    Munoz, N.3
  • 30
    • 0037454284 scopus 로고    scopus 로고
    • Epidemiologic studies of a necessary causal risk factor: human papillomavirus infection and cervical neoplasia
    • Schiffman M.H., and Castle P. Epidemiologic studies of a necessary causal risk factor: human papillomavirus infection and cervical neoplasia. J Natl Cancer Inst 95 6 (2003) E2
    • (2003) J Natl Cancer Inst , vol.95 , Issue.6
    • Schiffman, M.H.1    Castle, P.2
  • 31
    • 25844441585 scopus 로고    scopus 로고
    • A comparison of the HPV test and Pap smear as a second screening method for women with minor cytological abnormalities
    • Andersson S., Dillner L., Elfgren K., Mints M., Persson M., and Rylander E. A comparison of the HPV test and Pap smear as a second screening method for women with minor cytological abnormalities. Acta Obstet Gynecol Scand 84 10 (2004) 996-1000
    • (2004) Acta Obstet Gynecol Scand , vol.84 , Issue.10 , pp. 996-1000
    • Andersson, S.1    Dillner, L.2    Elfgren, K.3    Mints, M.4    Persson, M.5    Rylander, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.