Carboxymethylcellulose as a new carrier substance for intravitreal injection of reproducible amounts of triamcinolone

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 244, Issue 11, 2006, Pages 1385-1390

  Kube, T ^a   Sutter, M ^b   Trittler, R ^b   Feltgen, N ^a   Hansen, L L ^a   Agostini, Hansjuergen T ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Diabetes mellitus; Drug therapy; Eye; Macular degeneration; Pharmaceutical; Preservatives; Steroids; Therapeutics

Indexed keywords

CARBOXYMETHYLCELLULOSE; DRUG CARRIER; TRIAMCINOLONE; TRIAMCINOLONE ACETONIDE;

ARTICLE; CALCULATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; EYE; FILTRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INJECTION; PHYSICAL MODEL; PRIORITY JOURNAL; SEDIMENTATION;

CARBOXYMETHYLCELLULOSE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CARRIERS; FILTRATION; GLUCOCORTICOIDS; HUMANS; INJECTIONS; OPHTHALMIC SOLUTIONS; PHARMACEUTICAL PREPARATIONS; PRESERVATIVES, PHARMACEUTICAL; TRIAMCINOLONE ACETONIDE; VEHICLES; VITREOUS BODY;

EID: 33750991051     PISSN: 0721832X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00417-006-0326-2     Document Type: Article

References (49)

1. Alldredge CD, Garretson BR (2003) Intravitreal triamcinolone for the treatment of idiopathic juxtafoveal telangiectasis. Retina 23:113-116
2. Antcliff RJ, Spalton DJ, Stanford MR, Graham EM, Ffytche TJ, Marshall J (2001) Intravitreal triamcinolone for uveitic cystoid macular edema: An optical coherence tomography study. Ophthalmology 108:765-772
3. Beer PM, Bakri SJ, Singh RJ, Liu W, Peters GB 3rd, Miller M (2003) Intraocular concentration and pharmacokinetics of triamcinolone acetonide after a single intravitreal injection. Ophthalmology 110:681-686
4. Benhamou N, Massin P, Haouchine B, Audren F, Tadayoni R, Gaudric A (2003) Intravitreal triamcinolone for refractory pseudophakic macular edema. Am J Ophthalmol 135:246-249
5. Berry GK, Reed JB (2005) The effect of sedimentation on the concentration of triamcinolone acetonide. Invest Ophthalmol Vis Sci 46:492-
6. Burk SE, Da Mata AP, Snyder ME, Schneider S, Osher RH, Cionni RJ (2003) Visualizing vitreous using Kenalog suspension. J Cataract Refract Surg 29:645-651
7. Bynoe LA, Weiss JN (2003) Retinal endovascular surgery and intravitreal triamcinolone acetonide for central vein occlusion in young adults. Am J Ophthalmol 135:382-384
8. Challa JK, Gillies MC, Penfold PL, Gyory JF, Hunyor AB, Billson FA (1998) Exudative macular degeneration and intravitreal triamcinolone: 18 month follow up. Aust N Z J Ophthalmol 26:277-281
9. Conway MD, Canakis C, Livir-Rallatos C, Peyman GA (2003) Intravitreal triamcinolone acetonide for refractory chronic pseudophakic cystoid macular edema. J Cataract Refract Surg 29:27-33
10. Danis RP, Ciulla TA, Pratt LM, Anliker W (2000) Intravitreal triamcinolone acetonide in exudative age-related macular degeneration. Retina 20:244-250
11. Degenring RF, Jonas JB (2003) Intravitreal injection of triamcinolone acetonide as treatment for chronic uveitis. Br J Ophthalmol 87:361
12. Degenring RF, Kamppeter B, Kreissig I, Jonas JB (2003) Morphological and functional changes after intravitreal triamcinolone acetonide for retinal vein occlusion. Acta Ophthalmol Scand 81:548-550
13. Fernandez-Vigo J, Refojo MF, Jumblatt M (1989) Elimination of hydroxypropyl methylcellulose from the anterior chamber of the rabbit. J Cataract Refract Surg 15:191-195
14. Fernandez-Vigo J, Refojo MF, Verstraeten T (1990) Evaluation of a viscoelastic solution of hydroxypropyl methylcellulose as a potential vitreous substitute. Retina 10:148-152
15. Gillies MC, Simpson JM, Luo W, Penfold P, Hunyor AB, Chua W, Mitchell P, Billson F (2003) A randomized clinical trial of a single dose of intravitreal triamcinolone acetonide for neovascular age-related macular degeneration: One-year results. Arch Ophthalmol 121:667-673
16. Greenberg PB, Martidis A, Rogers AH, Duker JS, Reichel E (2002) Intravitreal triamcinolone acetonide for macular oedema due to central retinal vein occlusion. Br J Ophthalmol 86:247-248
17. Hida T, Chandler D, Arena JE, Machemer R (1986) Experimental and clinical observations of the intraocular toxicity of commercial corticosteroid preparations. Am J Ophthalmol 101:190-195
18. Ip M, Kahana A, Altaweel M (2003) Treatment of central retinal vein occlusion with triamcinolone acetonide: An optical coherence tomography study. Semin Ophthalmol 18:67-73
19. Jonas JB (2002) Concentration of intravitreally injected triamcinolone acetonide in aqueous humour. Br J Ophthalmol 86:1066
20. Jonas JB, Sofker A (2001) Intraocular injection of crystalline cortisone as adjunctive treatment of diabetic macular edema. Am J Ophthalmol 132:425-427
21. Jonas JB, Hayler JK, Panda-Jonas S (2000) Intravitreal injection of crystalline cortisone as adjunctive treatment of proliferative vitreoretinopathy. Br J Ophthalmol 84:1064-1067
22. Jonas JB, Hayler JK, Sofker A, Panda-Jonas S (2001) Intravitreal injection of crystalline cortisone as adjunctive treatment of proliferative diabetic retinopathy. Am J Ophthalmol 131:468-471
23. Jonas JB, Kreissig I, Degenring R (2002) Repeated intravitreal injections of triamcinolone acetonide as treatment of progressive exudative age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol 240:873-874
24. Jonas JB, Kreissig I, Degenring RF (2002) Intravitreal triamcinolone acetonide as treatment of macular edema in central retinal vein occlusion. Graefes Arch Clin Exp Ophthalmol 240:782-783
25. Jonas JB, Kreissig I, Degenring RF (2003) Intravitreal triamcinolone acetonide for pseudophakic cystoid macular edema. Am J Ophthalmol 136:384-386
26. Jonas JB, Kreissig I, Hugger P, Sauder G, Panda-Jonas S, Degenring R (2003) Intravitreal triamcinolone acetonide for exudative age related macular degeneration. Br J Ophthalmol 87:462-468
27. Jonas JB, Kreissig I, Sofker A, Degenring RF (2003) Intravitreal injection of triamcinolone for diffuse diabetic macular edema. Arch Ophthalmol 121:57-61
28. Jonas JB, Akkoyun I, Budde WM, Kreissig I, Degenring RF (2004) Intravitreal reinjection of triamcinolone for exudative age-related macular degeneration. Arch Ophthalmol 122:218-222
29. Karacorlu M, Ozdemir H, Karacorlu S (2003) Intravitreal triamcinolone acetonide for the treatment of chronic pseudophakic cystoid macular oedema. Acta Ophthalmol Scand 81:648-652
30. Kumagai K (2003) Introduction of a new method for the preparation of triamcinolone acetonide solution as an aid to visualization of the vitreous and the posterior hyaloid during pars plana vitrectomy. Retina 23:881-882
31. Liang C, Peyman GA, Serracarbassa P, Calixto N, Chow AA, Rao P (1998) An evaluation of methylated collagen as a substitute for vitreous and aqueous humor. Int Ophthalmol 22:13-18
32. Martidis A, Duker JS, Puliafito CA (2001) Intravitreal triamcinolone for refractory cystoid macular edema secondary to birdshot retinochoroidopathy. Arch Ophthalmol 119:1380-1383
33. Martidis A, Duker JS, Greenberg PB, Rogers AH, Puliafito CA, Reichel E, Baumal C (2002) Intravitreal triamcinolone for refractory diabetic macular edema. Ophthalmology 109:920-927
34. McCuen BW 2nd, Bessler M, Tano Y, Chandler D, Machemer R (1981) The lack of toxicity of intravitreally administered triamcinolone acetonide. Am J Ophthalmol 91:785-788
35. Moshfeghi DM, Kaiser PK, Scott IU, Sears JE, Benz M, Sinesterra JP, Kaiser RS, Bakri SJ, Maturi RK, Belmont J, Beer PM, Murray TG, Quiroz-Mercado H, Mieler WF (2003) Acute endophthalmitis following intravitreal triamcinolone acetonide injection. Am J Ophthalmol 136:791-796
36. Nelson ML, Martidis A (2003) Managing cystoid macular edema after cataract surgery. Curr Opin Ophthalmol 14:39-43
37. Nishimura A, Kobayashi A, Segawa Y, Sakurai M, Shirao E, Shirao Y, Sugiyama K (2003) Isolating triamcinolone acetonide particles for intravitreal use with a porous membrane filter. Retina 23:777-779
38. Park CH, Jaffe GJ, Fekrat S (2003) Intravitreal triamcinolone acetonide in eyes with cystoid macular edema associated with central retinal vein occlusion. Am J Ophthalmol 136:419-425
39. Parke DW (2003) Intravitreal triamcinolone and endophthalmitis. Am J Ophthalmol 136:918-919
40. Penfold PL (2002) Intravitreal triamcinolone in recurrence of choroidal neovascularisation. Br J Ophthalmol 86:600-601
41. Penfold PL, Gyory JF, Hunyor AB, Billson FA (1995) Exudative macular degeneration and intravitreal triamcinolone. A pilot study. Aust N Z J Ophthalmol 23:293-298
42. Peyman GA, Cheema R, Conway MD, Fang T (2000) Triamcinolone acetonide as an aid to visualization of the vitreous and the posterior hyaloid during pars plana vitrectomy. Retina 20:554-555
43. Ranson NT, Danis RP, Ciulla TA, Pratt L (2002) Intravitreal triamcinolone in subfoveal recurrence of choroidal neovascularisation after laser treatment in macular degeneration. Br J Ophthalmol 86:527-529
44. Rechtman E, Allen VD, Danis RP, Pratt LM, Harris A, Speicher MA (2003) Intravitreal triamcinolone for choroidal neovascularization in ocular histoplasmosis syndrome. Am J Ophthalmol 136:739-741
45. Roth DB, Chieh J, Spirn MJ, Green SN, Yarian DL, Chaudhry NA (2003) Noninfectious endophthalmitis associated with intravitreal triamcinolone injection. Arch Ophthalmol 121:1279-1282
46. Sakamoto T, Miyazaki M, Hisatomi T, Nakamura T, Ueno A, Itaya K, Ishibashi T (2002) Triamcinolone-assisted pars plana vitrectomy improves the surgical procedures and decreases the postoperative blood-ocular barrier breakdown. Graefes Arch Clin Exp Ophthalmol 240:423-429
47. Spaide RF, Sorenson J, Maranan L (2003) Combined photodynamic therapy with verteporfin and intravitreal triamcinolone acetonide for choroidal neovascularization. Ophthalmology 110:1517-1525
48. Sutter FK, Gillies MC (2003) Intravitreal triamcinolone for radiation-induced macular edema. Arch Ophthalmol 121:1491-1493
49. Young S, Larkin G, Branley M, Lightman S (2001) Safety and efficacy of intravitreal triamcinolone for cystoid macular oedema in uveitis. Clin Exp Ophthalmol 29:2-6