Platelet aggregation and P-selectin levels during exercise treadmill test in patients with ischaemic heart disease

Kardiologia Polska

Volumn 64, Issue 10, 2006, Pages 1094-1100

  Kobusiak Prokopowicz, Małgorzata ^a,b   Kuliczkowski, Wiktor ^a   Karolko, Bozena ^a   Prajs, Iwona ^a   Mazurek, Walentyna ^a  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

^b Wroclaw Medical University Katedra i Klinika Kardiologii   (Poland)

Author keywords

Coronary artery disease; P selectin; Platelet aggregation

Indexed keywords

ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE; ARACHIDONIC ACID; COLLAGEN; GLYCOSIDASE; PADGEM PROTEIN; POLY(ADENOSINE DIPHOSPHATE RIBOSE); THROMBIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOFLUOROMETRY; DEMOGRAPHY; DOSE RESPONSE; FEMALE; HUMAN; ISCHEMIC HEART DISEASE; MALE; PROTEIN EXPRESSION; THROMBOCYTE AGGREGATION; TREADMILL EXERCISE;

EID: 33750966771     PISSN: 00229032     EISSN: 00229032     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Antithrombotic Trialists' Collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. BMJ 2002; 324: 71-86.
2. Gum PA, Kottke-Marchant K, Poggio ED, et al. Profile and prevalence of aspirin resistance in patients with cardiovascular disease. Am J Cardiol 2001; 88: 230-5.
3. Ikarugi H, Taka T, Nakajima S, et al. Detection of a prothrombotic state after acute aerobic exercise. Thromb Res 1997; 85: 351-6.
4. Held C, Hjemdahl P, Rehnqvist N, et al. Haemostatic markers, inflammatory parameters and lipids in male and female patients in the Angina Prognosis Study in Stockholm (APSIS). A comparison with healthy controls. J Intern Med 1997; 241: 59-69.
5. Li N, Wallen NH, Hjemdahl P. Evidence for prothrombotic effects of exercise and limited protection by aspirin. Circulation 1999; 100: 1374-9.
6. Koenig W, Ernst E. Exercise and thrombosis. Coron Artery Dis 2000; 11: 123-7.
7. El-Sayed MS. Exercise and training effects on platelets in health and disease. Platelets 2002; 13: 261-6.
8. McEver RP. Leukocyte interactions mediated by P-selectin. In: Lipsky PE, Rothlein R, Kishimoto TK, et al. (eds). Structure, function and regulation of molecules involved in leukocyte adhesion. Springer Verlag 1991: 135-50.
9. Nicholson NS, Panzer-Knodle SG, Haas NF, et al. Assessment of platelet function assays. Am Heart J 1998; 135: S170-8.
10. Kobzar G, Mardla V, Ratsep I. Aspirin increases platelet sensitivity to adenosine diphosphate in patients with coronary artery disease. Platelets 1999; 10: 191-2.
11. Hamburger SA, McEver RP. GMP-140 mediates adhesion of stimulated platelets to neutrophils. Blood 1990; 75: 550-4.
12. Burger PC, Wagner DD. Soluble P-selectin, a marker of endothelial activation. ESC Congress 2004, Munich, abstract P485.
13. Wang JS. Intense exercise increases shear-induced platelet aggregation in men through enhancement of von Willbrand factor binding, glycoprotein IIb/IIIa activation, and P-selectin expression on platelets. Eur J Appl Physiol 2004: 91: 741-7.
14. Lindemann S, Klingel B, Fisch A, et al. Increased platelet sensitivity toward platelet inhibitors during physical exercise in patients with coronary artery disease. Thromb Res 1999; 93: 51-9.
15. Tanasescu M, Leitzmann MF, Rimm EB, et al. Exercise type and intensity in relation to coronary heart disease in men. JAMA 2002; 288: 1994-2000.
16. Hurlen M, Seljeflot I, Arnesen H. Increased platelet aggregability during exercise in patients with previous myocardial infarction. Lack of inhibition by aspirin. Thromb Res 2000; 99: 487-94.
17. Albert CM, Mittleman MA, Chae CU, et al. Triggering of sudden death from cardiac causes by vigorous exertion. N Engl J Med 2000; 343: 1355-61.
18. Cadroy Y, Pillard F, Sakariassen KS, et al. Strenuous but not moderate exercise increases the thrombotic tendency in healthy sedentary male volunteers. J Appl Physiol 2002; 93: 829-33.
19. Ikarugi H, Taka T, Nakajima S. Norepinephrine, but not epinephrine, enhances platelet reactivity and coagulation after exercise in humans. J Appl Physiol 1999; 86: 133-8.
20. Fletcher GF, Balady GJ, Amsterdam EA, et al. Exercise standards for testing and training: a statement for healthcare professionals from the American Heart Association. Circulation 2001; 104: 1694-740.