Prevalence of Human Cytomegalovirus UL97 D605E Mutation in Transplant Recipients in China

Transplantation Proceedings

Volumn 38, Issue 9, 2006, Pages 2926-2928

  Zhou, L ^a   Fan, J ^a   Zheng, S S ^a   Ma, W H ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EDETIC ACID; GANCICLOVIR;

ANTIBIOTIC RESISTANCE; ARTICLE; BLOOD SAMPLING; CHINA; CODON; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; GENE AMPLIFICATION; GRAFT RECIPIENT; HUMAN; HUMAN CYTOMEGALOVIRUS; MUTATIONAL ANALYSIS; ORGAN TRANSPLANTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEROPREVALENCE; VIRUS MUTANT; VIRUS MUTATION; WILD TYPE;

BONE MARROW TRANSPLANTATION; CHINA; CODON; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DNA PRIMERS; GENE AMPLIFICATION; HUMANS; KIDNEY TRANSPLANTATION; MUTATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); POSTOPERATIVE COMPLICATIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VARIATION (GENETICS);

EID: 33750965414     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2006.08.161     Document Type: Article

References (12)

1. Opelz G., Dohler B., and Ruhenstroth A. Cytomegalovirus prophylaxis and graft outcome in solid organ transplantation: a collaborative transplant study report. Am J Transplant 4 (2004) 928
2. Michel D., and Mertens T. The UL97 protein kinase of human cytomegalovirus and homologues in other herpesviruses: impact on virus and host. Biochim Biophys Acta 1697 (2004) 169
3. Baldanti F., Lurain N., Gerna G., et al. Clinical and biologic aspects of human cytomegalovirus resistance to antiviral drugs. Hum Immunol 65 (2004) 403
4. Hantz S., Michel D., Fillet A.M., et al. Early selection of a new UL97 mutant with a severe defect of ganciclovir phosphorylation after valaciclovir prophylaxis and short-term ganciclovir therapy in a renal transplant recipient. Antimicrob Agents Chemother 49 (2005) 1580
5. Zhou L., Qian J., Cai T., et al. Study on cytomegalovirus gene mutations conferring resistance to ganciclovir in heart and lung transplant patients. Chinese J Infect Dis 20 (2002) 37-40
6. Sarasini A., Baldanti F., Furione M., et al. Double resistance to ganciclovir and foscarnet of four human cytomegalovirus strains recovered from AIDS patients. J Med Virol 47 (1995) 237
7. Lurain N.S., Bhorade S.M., Pursell K.J., et al. Analysis and characterization of antiviral drug-resistant cytomegalovirus isolates from solid organ transplant recipients. J Infect Dis 186 (2002) 760
8. Alain S., Mazeron M.C., Pepin J.M., et al. Value of a new rapid non-radioactive sequencing method for analysis of the cytomegalovirus UL97 gene in ganciclovir-resistant strains. J Virol Methods 51 (1995) 241
9. Hu H., Jabs D.A., Forman M.S., et al. Comparison of cytomegalovirus (CMV) UL97 gene sequences in the blood and vitreous of patients with acquired immunodeficiency syndrome and CMV retinitis. J Infec Dis 185 (2002) 861
10. Puch S.S., Ochoa C., Carballal G., et al. Cytomegalovirus UL97 mutations associated with ganciclovir resistance in immunocompromised patients from Argentina. J Clin Virol 30 (2004) 271
11. Lurain N., Weinberg A., Crumpacker C., et al. Sequencing of cytomegalovirus UL97 gene for genotypic antiviral resistance testing. Antimicrob Agents Chemother 45 (2001) 2775
12. Chou S., Van Wechel L.C., Lichy H.M., et al. Phenotyping of cytomegalovirus drug resistance mutations by using recombinant viruses incorporating a reporter gene. Antimicrob Agents Chemother 49 (2005) 2710