Ramelteon for insomnia in two youths with autistic disorder

Journal of Child and Adolescent Psychopharmacology

Volumn 16, Issue 5, 2006, Pages 631-636

  Stigler, Kimberly A ^a   Posey, David J ^a   McDougle, Christopher J ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARIPIPRAZOLE; CLONIDINE; DIPHENHYDRAMINE; FLUOXETINE; GABAPENTIN; GUANFACINE; HORMONE RECEPTOR STIMULATING AGENT; MELATONIN; METHYLPHENIDATE; OLANZAPINE; PAROXETINE; QUETIAPINE; RAMELTEON; RISPERIDONE; SERTRALINE; TRAZODONE; UNCLASSIFIED DRUG;

ADULT; AROUSAL; ARTICLE; AUTISM; CASE REPORT; CLINICAL FEATURE; CLINICAL GLOBAL IMPRESSION SCALE; CLINICAL TRIAL; DAYTIME SOMNOLENCE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; HUMAN; INSOMNIA; MALE; OPEN STUDY; SCHOOL CHILD; SEDATION; SIDE EFFECT; SLEEP INDUCTION; SYMPTOMATOLOGY; TREATMENT DURATION; TREATMENT RESPONSE;

ADOLESCENT; AUTISTIC DISORDER; CHILD; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; HUMANS; INDENES; MALE; SLEEP INITIATION AND MAINTENANCE DISORDERS;

EID: 33750956249     PISSN: 10445463     EISSN: None     Source Type: Journal    
DOI: 10.1089/cap.2006.16.631     Document Type: Article

References (27)

1. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR). Washington, DC, American Psychiatric Association, 2000.
2. Corkum P, Tannock R, Moldofsky H: Sleep disturbances in children with attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry 37:637-646, 1998.
3. Diomedi M, Curatolo P, Scalise A, Placidi F, Caretto F, Gigli GL: Sleep abnormalities in mentally retarded autistic subjects, Down's syndrome with mental retardation and normal subjects. Brain Dev 21:548-553, 1999.
4. Elia M, Ferri R, Musumeci SA, Del Gracco S, Bottitta M, Scuderi C, Miano G, Panerai S, Bertrand T, Grubar JC: Sleep in subjects with autistic disorder: A neurophysiological and psychological study. Brain Dev 22:88-92, 2000.
5. Erman M, Seiden D, Zammit G, Sainati S, Zhang J: An efficacy, safety, and dose-response study of ramelteon in patients with chronic primary insomnia. Sleep Med 7:17-24, 2006.
6. Guy W: ECDEU Assessment Manual for Psychopharmacology. Washington, D.C., DHEW, NMH, 1976.
7. Hayashi E. Effects of melatonin on sleep-wake rhythm: The sleep diary of an autistic male. Psychiat Clin Neurosci 54:383-384, 2000.
8. Hering E, Epstein R, Elroy S, Iancu DR, Zelnik N: Sleep patterns in autistic children. J Autism Dev Disorders 29:143-147, 1999.
9. Honomichl RD, Goodlin-Jones BL, Burnham M, Gaylor E, Anders TF: Sleep patterns of children with pervasive developmental disorders. J Autism Dev Disord 32:553-561, 2002.
10. Horrigan JP, Barnhill LJ: More on melatonin [letter to the editor]. J Am Acad Child Adolesc Psychiatry 36:1014, 1997.
11. Hoshino Y, Watanabe H, Yashima Y, Kaneko M, Kumashiro H: An investigation on sleep disturbance of autistic children. Folia Psychiatr Neurol Jpn 38:45-52, 1984.
12. Kato K, Harai K, Nishiyama K, Uchikawa O, Fukatsu K, Ohkawa S, Kawamata Y, Hinuma S, Miyamoto M: Neurochemical properties of ramelteon (TAK-375), a selective MT1/MT2 receptor agonist. Neuropharmacology 48:301-310, 2005.
13. Kulman G, Lissoni P, Rovelli F, Roselli MG, Brivio F, Sequeri P: Evidence of pineal endocrine hypofunction in autistic children. Neuroendocrinol Lett 21:31-34, 2000.
14. Lancioni GE, O'Reilly MF, Basili G: Review of strategies for treating sleep problems in persons with severe or profound mental retardation or multiple handicaps. Am J Mental Retard 104:170-186, 1999.
15. Malow BA: Sleep disorders, epilepsy, and autism. Mental Retard Devel Disabilities Res Rev 10:122-125, 2004.
16. McDougle CJ, Erickson CA, Stigler KA, Posey DJ: Neurochemistry in the pathophysiology of autism. J Clin Psychiatry 66 Suppl 10:9-18, 2005.
17. Nir I, Meir D, Zilber N, Knobler H, Hadjez J, Lerner Y: Brief report: Circadian melatonin, thyroid-stimulating hormone, prolactin, and cortisol levels in serum of young adults with autism. J Autism Dev Disord 25:641-654, 1995.
18. Paavonen EJ, Nieminen-von Wendt T, Vanhala R, Aronen ET, von Wendt L: Effectiveness of melatonin in the treatment of sleep disturbances in children with Asperger's disorder. J Child Adolesc Psychopharmacol 13:83-95, 2003.
19. Patzold LM, Richdale AL, Tonge BJ: An investigation into sleep characteristics of children with autism and Asperger's disorder. J Paediatr Child Health 34:528-533, 1998.
20. Polimeni AL, Richdale AL, Francis AJP: A survey of sleep problems in autism, Asperger's disorder and typically developing children. J Intellect Disabil 49:260-268, 2005.
21. Richdale AL: Sleep problems in autism: Prevalence, cause, and intervention. Dev Med Child Neurol 41:60-66, 1999.
22. Richdale AL: Sleep in autism and Asperger's syndrome. In: Sleep Disturbance in Children and Adolescents with Disorders of Development: Its Significance and Management. Edited by Stores G, Wiggs L. London, Mac Keith Press, pp 181-191, 2001.
23. Roth T, Stubbs C, Walsh JK: Ramelteon (TAK-375), a selective MT1/MT2-receptor agonist, reduces latency to persistent sleep in a model of transient insomnia related to a novel sleep environment. Sleep 28:303-307, 2005.
24. Stigler KA, Posey DJ, McDougle CJ: Recent advances in the pharmacotherapy of autism. Expert Rev Neurotherapeutics 2:499-510, 2002.
25. Tiara M, Takase M, Sasaki J: Sleep disorder in children with autism. Psychiatry Clin Neurosci 52:182-183, 1998.
26. Tordjman S, Anderson GM, Pichard N, Charbuy H, Touitou Y: Nocturnal excretion of 6-sulphatoxymelatonin in children and adolescents with autistic disorder. Biol Psychiatry 57:134-138, 2005.
27. Wiggs L, Stores G: Severe sleep disturbance and daytime challenging behavior in children with severe learning disabilities. J Intellect Disabil Res 40:518-528, 1996.