The effect of gamma irradiation on anterior cruciate ligament allograft biomechanical and biochemical properties in the caprine model at time zero and at 6 months after surgery

American Journal of Sports Medicine

Volumn 34, Issue 11, 2006, Pages 1747-1755

  Schwartz, Herbert E ^a,b   Matava, Matthew J ^c,d,g   Proch, Frank S ^a,b   Butler, Charles A ^c,e   Ratcliffe, Anthony ^f   Levy, Martin ^a   Butler, David L ^a  

^a 705 Engineering Research Center   (United States)

^b Schwartz Biomedical LLC   (United States)

^c Deaconess Hospital Cincinnati   (United States)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e North Florida Sportsmedicine and Orthopaedic Center   (United States)

^f Synthasome Inc   (United States)

^g East Pavilion   (United States)

Author keywords

Allograft; Anterior cruciate ligament (ACL); Biomechanics; Gamma irradiation

Indexed keywords

ALLOGRAFT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTERIOR CRUCIATE LIGAMENT; ARTICLE; BIOCHEMISTRY; BIOMECHANICS; CONTROLLED STUDY; EXPERIMENTAL MODEL; FEMALE; FEMUR; FORCE; GAMMA IRRADIATION; GOAT; LABORATORY TEST; LIGAMENT SURGERY; NONHUMAN; PATELLA TENDON; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RADIATION DOSE; RIGIDITY; STRUCTURE ANALYSIS; TENDON GRAFT; TENSILE STRENGTH; TIBIA; TIME; VISCOELASTICITY;

ANIMALS; ANTERIOR CRUCIATE LIGAMENT; BONE-PATELLAR TENDON-BONE GRAFT; FEMALE; GAMMA RAYS; GLYCOSAMINOGLYCANS; GOATS; HYDROXYPROLINE; MODELS, ANIMAL; PATELLAR LIGAMENT; PROTEOGLYCANS; RANDOM ALLOCATION; STERILIZATION; TENSILE STRENGTH; TIME FACTORS; TRANSPLANTATION, HOMOLOGOUS; WEIGHT-BEARING;

EID: 33750945308     PISSN: 03635465     EISSN: 15523365     Source Type: Journal    
DOI: 10.1177/0363546506288851     Document Type: Article

References (47)

1. American Association of Tissue Banks. AAOS and AATB Information for Patients. McLean, Va: American Association of Tissue Banks. 2003.
2. Asselmeier MA, Caspari RB, Bottenfield S. A review of allograft processing and sterilization techniques and their role in transmission of the human immunodeficiency virus. Am J Sports Med. 1993;21:170-175.
3. Bailey AJ, Tromans WJ. Effect of ionizing radiation on the ultrastructure of collagen fibers. Radiation Res. 1964;23:145-155.
4. Bartlett RJ, Clatworthy MG, Nguyen TN. Graft selection in reconstruction of the anterior cruciate ligament. J Bone Joint Surg Br. 2001;83:625-634.
5. Bright RW, Smarsh JD, Gambill VM. Sterilization of human bone by irradiation. In: Friedlaender GE, ed. Osteochondral Allograft Biology, Banking, and Clinical Applications. Boston, Mass: Little, Brown; 1983:223-232.
6. Butler DL, Oster DM, Feder SM, Grood ES, Noyes FR. Effects of gamma irradiation on the biomechanics of patellar tendon allografts of the ACL of the goat. Trans Orthop Res Soc. 1991;16:205.
7. Centers for Disease Control and Prevention. Transmission of HIV Through Bone Transplantation: Case Report and Public Health Recommendations. Atlanta, Ga: Centers for Disease Control and Prevention; 1988.
8. Centers for Disease Control and Prevention. Update: Allograft-associated bacterial infections - United States, 2002. Morb Mortal Wkly Rep. 2002;51:207-210.
9. Chimich D, Shrive N, Frank C, Marchuk L, Bray R. Water content alters viscoelastic behaviour of the normal adolescent rabbit medial collateral ligament. J Biomech. 1992;25:831-837.
10. Christensen EA, Kristensen H, Sehestad K. Radiation sterilization. In: Russel AD, Hugo WB, Ayliffe GA, eds. Principles and Practices of Disinfection, Preservation, and Sterilization. Oxford, England: Blackwell Scientific Publications; 1982:513-533.
11. Conway B, Tomford W, Mankin HJ, Hirsch MS, Schooley RT. Radiosensitivity of HIV-1: potential application to sterilization of bone allografts. AIDS. 1991;5:608-609.
12. Darr ES, Moudgil T, Meyer RD. Transient high levels of viremia in patients with primary human immunodeficiency virus type 1 infection. New Engl J Med. 1991;324:961-964.
13. Eyre DR, Dickson IR, Van Ness K. Collagen cross-linking in human bone and articular cartilage: age-related changes in the content of mature hydroxypyridinium residues. Biochem J. 1988;252:495-500.
14. Eyre DR, Koob TJ, Van Ness KP. Quantitation of hydroxypyridinium crosslinks in collagen by high-performance liquid chromatography. Anal Biochem. 1984;137:380-388.
15. Eyre DR, Paz MA, Gallop PM. Cross-linking in collagen and elastin. Ann Rev Biochem. 1984;53:717-748.
16. Farndale RW, Sayers CA, Barrett AJ. A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures. Connect Tissue Res. 1982;9:247-248.
17. Feder SF, Butler DL, Holden JP. A technique for evaluating the contributions of knee structures to knee mechanics in the anterior cruciate reconstructed knee. J Orthop Res. 1993;11:448-451.
18. Fideler BM, Vangsness CT, Lu B, Orlando C, Moore T. Gamma irradiation: effects on biomechanical properties of human bone-patellar tendon-bone allografts. Am J Sports Med. 1995;23:643-646.
19. Fideler BM, Vangsness CT Jr, Moore T, Li Z, Rasheed S. Effects of gamma irradiation on the human immunodeficiency virus: a study in frozen human bone-patellar ligament-bone grafts obtained from infected cadavera. J Bone Joint Surg Am. 1994;76:1032-1035.
20. Frank CB, Eyre DR, Shrive NG. Hydroxypyridinium cross-link deficiency in ligament scar. Trans Orthop Res Soc. 1994;19:13.
21. Getelman MH, Friedman MJ. Revision anterior cruciate ligament reconstruction surgery. J Am Acad Orthop Surg. 1999;7:189-198.
22. Gibbons MJ, Butler DL, Grood ES, Bylski-Austrow DI, Levy MS, Noyes FR. Effects of gamma irradiation on the initial mechanical and material properties of goat bone-patellar tendon-bone allografts. J Orthop Res. 1991;9:209-218.
23. Guilak F, Ratcliffe A, Lane N, Rosenwasser MP, Mow VC. Mechanical and biochemical changes in the superficial zone of articular cartilage in canine experimental osteoarthritis. J Orthop Res. 1994;12:474-484.
24. Hamm RH, Donnell HD Jr, Watkins W. An update on the epidemiology of AIDS in Missouri. Mo Med. 1994;91:132-136.
25. Haridas B, Butler DL, Doxey CM, Proch FS, Schwartz HE. Effects of allograft gamma irradiation on the cyclic anterior/posterior response of the reconstructed goat knee. Trans Orthop Res Soc. 1994;19:627.
26. Haut RC, Powlison AC. The effects of test environment and cyclic stretching on the failure properties of human patellar tendons. J Orthop Res. 1990;8:532-540.
27. Holden JP, Grood ES, Butler DL, et al. Biomechanics of fascia lata ligament replacements: early postoperative changes in the goat. J Orthop Res. 1988;6:639-647.
28. Jackson DW, Grood ES, Arnoczky SP, Butler DL, Simon TM. Freeze dried anterior cruciate ligament allografts: preliminary studies in a goat model. Am J Sports Med. 1987;15:295-303.
29. Jackson DW, Grood ES, Cohn BT, Arnoczky SP, Simon TM, Cummings JF. The effects of in situ freezing on the anterior cruciate ligament: an experimental study in goats. J Bone Joint Surg Am. 1991;73:201-213.
30. Jackson DW, Grood ES, Wilcox P, Butler DL, Simon TM, Holden JP. The effects of processing techniques on the mechanical properties of bone-anterior cruciate ligament-bone allografts: an experimental study in goats. Am J Sports Med. 1988;16:101-105.
31. Koh WY, Morehouse CT, Chandler VL. Relative resistances of microorganisms to cathode rays, I: non-sporeforming bacteria. Appl Microbiol. 1956;4:143-146.
32. Meeker I, Gross RE. Low-temperature sterilization of organic tissue by high-voltage cathode ray irradiation. Science. 1951;114:283.
33. Nin JR, Leyes M, Schweitzer D. Anterior cruciate ligament reconstruction with fresh-frozen patellar tendon allografts: sixty cases with 2 years' minimum follow-up. Knee Surg Sports Traumatol Arthrosc. 1996;4:137-142.
34. Noyes FR, Barber-Westin SD. Arthroscopic-assisted allograft anterior cruciate ligament reconstruction in patients with symptomatic arthrosis. Arthroscopy. 1997;13:24-32.
35. Noyes FR, Barber-Westin SD. Reconstruction of the anterior cruciate ligament with human allograft: comparison of early and later results. J Bone Joint Surg Am. 1996;78:524-537.
36. Noyes FR, Butler DL, Grood ES, Zernicke RF, Hefzy MS. Biomechanical analysis of human ligament grafts used in knee-ligament repairs and reconstructions. J Bone Joint Surg Am. 1984;66:344-352.
37. Ohno K, Yasuda K, Yamamoto N, Kaneda K, Hayashi K. Effects of complete stress-shielding on the mechanical properties and histology of in situ frozen patellar tendon. J Orthop Res. 1993;11:592-602.
38. Rasmussen TJ, Feder S, Butler D, Noyes F. The effects of 4 Mrad of gamma irradiation on the initial mechanical properties of bone-patellar tendon-bone grafts. Arthroscopy. 1994;10:188-197.
39. Salehpour A, Butler DL, Proch FS. Dose-dependent response of gamma irradiation on mechanical properties of goat bone-patellar tendon-bone allografts. Trans Orthop Res Soc. 1994;19:557.
40. Salehpour A, Butler DL, Proch FS, et al. Dose-dependent response of gamma irradiation on mechanical properties and related biochemical composition of goat bone-patellar tendon-bone allografts. J Orthop Res. 1995;13:898-906.
41. Salehpour A, Butler DL, Proch FS, Schwartz HE. Dose-dependent effects of gamma irradiation on ACL allograft viscoelasticity in the goat. Trans Orthop Res Soc. 1995;20:633.
42. Schenck RC, Butler DL, Feder SM, Von Haefen LM, Noyes FR. Biomechanics of early healing extraarticular ligament vs tendon defects in the goat model. Trans Orthop Res Soc. 1991;37:161.
43. Seibel MJ, Macaulay W, Jelsma R, Saed-Nejad F, Ratcliffe A. Antigenic properties of keratan sulfate: influence of antigen structure, monoclonal antibodies, and antibody valency. Arch Biochem Biophys. 1992;296:410-418.
44. Shelton WR, Papendick L, Dukes AD. Autograft versus allograft anterior cruciate ligament reconstruction. Arthroscopy. 1997;13:446-449.
45. Stegemann H, Stalder K. Determination of hydroxyproline. Clin Chim Acta. 1967;18:267-273.
46. Tsuchida T, Yasuda K, Kaneda K, et al. Effects of in situ freezing and stress-shielding on the ultrastructure of rabbit patellar tendons. J Orthop Res. 1997;15:904-910.
47. Wright K, Trump J. Co-operative studies in the use of ionizing radiation for sterilization and preservation of biological tissue, twenty years experience. In: Sterilization and Preservation of Biological Tissues by Ionizing Radiation. Vienna, Austria: International Atomic Energy Agency; 1969:107-118.