A practical and selective reduction of nitroarenes using elemental sulfur and mild base

Tetrahedron Letters

Volumn 47, Issue 51, 2006, Pages 9095-9097

  McLaughlin, Maureen A ^a   Barnes, David M ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANILINE DERIVATIVE; AROMATIC NITRO COMPOUND; BASE; BENZENE DERIVATIVE; HYDROGEN; METAL DERIVATIVE; SULFUR;

ARTICLE; SYNTHESIS; TECHNIQUE;

EID: 33750934962     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2006.10.079     Document Type: Article

References (25)

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23. HPLC area % ratio at 225 nm.
24. Although the reaction with benzylamine showed 89% conversion by HPLC area % ratio, the assay was complicated by the presence of benzylamine by-products.
25. The mechanism of the reduction of nitroarenes in propylamine solvent has been proposed to proceed through a nitroaromatic radical anion by a single electron transfer mechanism (see Ref. 8).