Meta-analysis of preoperative antiseptic bathing in the prevention of surgical site infection

British Journal of Surgery

Volumn 93, Issue 11, 2006, Pages 1335-1341

  Webster, J ^a,b   Osborne, S ^a  

^a QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

^b ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; CHLORHEXIDINE GLUCONATE; PLACEBO;

ALLERGIC REACTION; ANTISEPSIS; ARTICLE; BATH; CLINICAL TRIAL; COST BENEFIT ANALYSIS; DRUG COST; HUMAN; INFECTION RISK; META ANALYSIS; MORTALITY; PREOPERATIVE CARE; PRIORITY JOURNAL; SURGICAL INFECTION; SURGICAL TECHNIQUE; SYSTEMATIC REVIEW; TREATMENT OUTCOME;

ANTI-INFECTIVE AGENTS, LOCAL; BATHS; CONTROLLED CLINICAL TRIALS; HUMANS; PREOPERATIVE CARE; SURGICAL WOUND INFECTION;

EID: 33750931919     PISSN: 00071323     EISSN: 13652168     Source Type: Journal    
DOI: 10.1002/bjs.5606     Document Type: Article

References (21)

1. Smyth ET, Emmerson AM. Surgical site infection surveillance. J Hosp Infect 2000; 45: 173-184.
2. Byrne DJ, Napier A, Phillips G, Cuschieri A. Effects of whole body disinfection on skin flora in patients undergoing elective surgery. J Hosp Infect 1991; 17: 217-222.
3. Kaiser AB, Kernodle DS, Barg NL, Petracek MR. Influence of preoperative showers on staphylococcal skin colonization: a comparative trial of antiseptic skin cleansers. Ann Thorac Surg 1988; 45: 35-38.
4. Paulson DS. Efficacy evaluation of a 4% chlorhexidine gluconate as a full-body shower wash. Am J Infect Control 1993; 21: 205-209.
5. Cruse PJ, Foord R. The epidemiology of wound infection. A 10-year prospective study of 62,939 wounds. Surg Clin North Am 1980; 60: 27-40.
6. Brady LM, Thomson M, Palmer MA, Harkness JL. Successful control of endemic MRSA in a cardiothoracic surgical unit. Med J Aust 1990; 152: 240-245.
7. Wilcox MH, Hall J, Pike H, Templeton PA, Fawley WN, Parnell P et al. Use of perioperative mupirocin to prevent methicillin-resistant Staphylococcus aureus (MRSA) orthopaedic surgical site infections. J Hosp Infect 2003; 54: 196-201.
8. Thomas L, Maillard JY, Lambert RJ, Russell AD. Development of resistance to chlorhexidine diacetate in Pseudomonas aeruginosa and the effect of a 'residual' concentration. J Hosp Infect 2000; 46: 297-303.
9. Beaudouin E, Kanny G, Morisset M, Renaudin JM, Mertes M, Laxenaire MC et al. Immediate hypersensitivity to chlorhexidine: literature review. Allerg Immunol (Paris) 2004; 36: 123-126.
10. Krautheim AB, Jermann TH, Bircher AJ. Chlorhexidine anaphylaxis: case report and review of the literature. Contact Dermatitis 2004; 50: 113-116.
11. Higgins JPT, Green S (eds). Cochrane Handbook for Systematic Reviews of Interventions 4-2-5 (updated May 2005). In The Cochrane Library, 2005; Issue 3. John Wiley & Sons: Chichester.
12. Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med 2002; 21: 1539-1558.
13. Byrne DN, Napier A, Cuschieri A. The value of whole body disinfection in the prevention of post-operative wound infection in clean and potentially contaminated surgery. A prospective, randomised, double blind, placebo controlled trial. Surg Res Comm 1992; 12: 43-52.
14. Hayek LJ, Emerson JM, Gardner AM. A placebo-controlled trial of the effect of two preoperative baths or showers with chlorhexidine detergent on postoperative wound infection rates. J Hosp Infect 1987; 10: 165-172.
15. Earnshaw JJ, Berridge DC, Slack RC, Makin GS, Hopkinson BR. Do preoperative chlorhexidine baths reduce the risk of infection after vascular reconstruction? Eur J Vasc Surg 1989; 3: 323-326.
16. Randall PE, Ganguli L, Marcuson RW. Wound infection following vasectomy. Br J Urol 1983; 55: 564-567.
17. Rotter ML, Larsen SO, Cooke EM, Dankert J, Daschner F, Greco D et al. A comparison of the effects of preoperative whole-body bathing with detergent alone and with detergent containing chlorhexidine gluconate on the frequency of wound infections after clean surgery. The European Working Party on Control of Hospital Infections. J Hosp Infect 1988; 11: 310-320.
18. Wihlborg O. The effect of washing with chlorhexidine soap on wound infection rate in general surgery. A controlled clinical study. Ann Chir Gynaecol 1987; 76: 263-265.
19. Whiting-O'Keefe QE, Henke C, Simborg DW. Chosing the correct unit of analysis in medical care experiments. Med Care 1984; 22: 1101-1114.
20. Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR. Guideline for prevention of surgical site infection, 1999. Hospital Infection Control Practices Advisory Committee. Infect Control Hosp Epidemiol 1999; 20: 250-278.
21. Webster J, Osborne S. Preoperative bathing or showering with skin antiseptics to prevent surgical site infection. Cochrane Database Syst Rev 2006; 2: CD004985.