Pancreas transplant alone has beneficial effects on retinopathy in type 1 diabetic patients

Diabetologia

Volumn 49, Issue 12, 2006, Pages 2977-2982

  Giannarelli, R ^a   Coppelli, A ^a   Sartini, M S ^a   Del Chiaro, M ^a   Vistoli, F ^a   Rizzo, G ^a   Barsotti, M ^a   Del Prato, S ^a   Mosca, F ^a   Boggi, U ^a   Marchetti, P ^a,b  

^a UNIVERSITY OF PISA   (Italy)

^b CISANELLO HOSPITAL   (Italy)

Author keywords

Diabetic retinopathy; Immunosuppression; Pancreas transplantation

Indexed keywords

ADULT; ARTICLE; CATARACT; CLINICAL ARTICLE; CONTROLLED STUDY; COURSE EVALUATION; DIABETIC PATIENT; DIABETIC RETINOPATHY; DISEASE EXACERBATION; FEMALE; FOLLOW UP; GENERAL CONDITION DETERIORATION; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; INTRAOCULAR PRESSURE; MALE; MEDICAL ASSESSMENT; OPHTHALMOSCOPY; OVERALL SURVIVAL; PANCREAS ISLET TRANSPLANTATION; PATIENT ASSESSMENT; PRIORITY JOURNAL; RETINA ANGIOGRAPHY; RETINA FLUORESCEIN ANGIOGRAPHY; SLIT LAMP; VISUAL ACUITY;

ADULT; DIABETES MELLITUS, TYPE 1; DIABETIC RETINOPATHY; FEMALE; FLUORESCEIN ANGIOGRAPHY; FOLLOW-UP STUDIES; HUMANS; INTRAOCULAR PRESSURE; MALE; MIDDLE AGED; PANCREAS TRANSPLANTATION; VISUAL ACUITY;

EID: 33750928972     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-006-0463-5     Document Type: Article

References (34)

1. Porta M, Bandello F (2002) Diabetic retinopathy. A clinical update. Diabetologia 45:1617-1634
2. Klein R (2002) Prevention of visual loss from diabetic retinopathy. Surv Ophthalmol 47(Suppl 2):S246-S252
3. Aiello LP, Gardner TW, King GL et al (1998) Diabetic retinopathy. Diabetes Care 21:143-156
4. The Diabetes Control and Complications Trial Research Group (1993) The effect of intensive treatment of diabetes on the development of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 329:977-986
5. Lloyd CE, Klein R, Maser RE, Kuller LH, Becker DJ, Orchard TJ (1995) The progression of retinopathy over 2 years: the Pittsburgh Epidemiology of Diabetes Complications (EDC) Study. J Diab Comp 9:140-148
6. Scheider A, Meyer-Schwickerath E, Nusser J, Land W, Landgraf R (1991) Diabetic retinopathy and pancreas transplantation: a 3-year follow-up. Diabetologia 34:95-99
7. Sutherland DE, Dunn DL, Goetz FC et al (1989) A 10-year experience with 290 pancreas transplants at a single institution. Ann Surg 210:274-288
8. Ramsay R, Goetz F, Sutherland DE et al (1988) Progression of diabetic retinopathy after pancreas transplantation for insulin dependent diabetes mellitus. N Engl J Med 318:208-214
9. Zech JC, Trepsat D, Gain-Gueugnon M, Lefrancois N, Martin X, Dubernard JM (1991) Ophthalmological follow-up of type 1 (insulin-dependent) diabetic patients after kidney and pancreas transplantation. Diabetologia 34(Suppl 1):S89-S91
10. Koznarova R, Saudek F, Sosna T et al (2000) Beneficial effect of pancreas and kidney transplantation on advanced diabetic retinopathy. Cell Transplant 9:903-908
11. Pearce IA, Ilango B, Sells RA, Wong D (2000) Stabilisation of diabetic retinopathy following simultaneous pancreas and kidney transplant. Br J Ophthalmol 84:736-740
12. Giannarelli R, Coppelli A, Sartini MS et al (2005) Effects of pancreas-kidney transplantation on diabetic retinopathy. Transpl Int 18:619-622
13. Konigsrainer A, Miller K, Steurer W et al (1991) Does pancreas transplantation influence the course of diabetic retinopathy? Diabetologia 34(Suppl 1):S86-S88
14. Chow VC, Pai RP, Chapman JR et al (1999) Diabetic retinopathy after combined kidney-pancreas transplantation. Clin Transplant 13:356-362
15. Pai RP, Mitchell P, Chow VC et al (2000) Posttransplant cataract: lessons from kidney-pancreas transplantation. Transplantation 69:1108-1114
16. Giannarelli R, Coppelli A, Sartini MS et al (2002) Early improvement of unstable diabetic retinopathy after solitary pancreas transplantation. Diabetes Care 25:2358-2359
17. Aldington SJ, Kohner EM, Meuer S, Klein R, Sjolie AK (1995) Methodology for retinal photography and assessment of diabetic retinopathy: the EURODIAB IDDM complications study. Diabetologia 38:437-444
18. Robertson RP, Davis C, Larsen J, Stratta R, Sutherland DE; American Diabetes Association (2003) Pancreas transplantation for patients with type 1 diabetes. Diabetes Care 26(Suppl 1):S120
19. Sutherland DE (1997) Pancreas transplantation as a treatment for diabetes: indications and outcome. Curr Ther Endocrinol Metab 6:469-496
20. Stratta RJ, Weide LG, Sindhi R et al (1997) Solitary pancreas transplantation. Experience with 62 consecutive cases. Diabetes Care 20:362-368
21. Boggi U, Vistoli F, Del Chiaro M et al (2004) A simplified technique for the en-bloc procurement of abdominal organs that is suitable for pancreas and small-bowel transplantation. Surgery 135:629-641
22. Boggi U, Vistoli F, Del Chiaro M et al (2004) Retroperitoneal pancreas transplantation with portal-enteric drainage. Transplant Proc 36:571-574
23. Early Treatment Diabetic Retinopathy Study Research Group (1978) Photocoagulation treatment of proliferative diabetic retinopathy. DRS report no 2. Ophthalmology 85:82-106
24. Chylack LT Jr, Wolfe JK, Singer DM et al (1993) The lens opacities classification system III. The Longitudinal Study of Cataract Study Group. Arch Ophthalmol 111:831-836
25. Laatikainen L, Summanen P, Ekstrand A, Groop L (1993) Ophthalmological follow-up of diabetic patients after kidney transplantation. Ger J Ophthalmol 2:24-27
26. Coppelli A, Giannarelli R, Mariotti R et al (2003) Pancreas transplant alone determines early improvement of cardiovascular risk factors and cardiac function in type 1 diabetic patients. Transplantation 76:974-976
27. Coppelli A, Giannarelli R, Vistoli F et al (2005) The beneficial effects of pancreas transplant alone on diabetic nephropathy. Diabetes Care 28:1366-1370
28. Kohner EM (1997) Diabetic retinopathy and high blood pressure: defining the risk. Am J Hypertens 10:181S-183S
29. Ciulla TA, Amador AG, Zinman B (2003) Diabetic retinopathy and diabetic macular edema: pathophysiology, screening, and novel therapies. Diabetes Care 26:2653-2664
30. Yamagishi S, Nakamura K, Matsui T, Sato T, Takeuchi M (2006) Potential utility of statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in diabetic retinopathy. Med Hypotheses 66:1019-1021
31. Miljanovic B, Glynn RJ, Nathan DM, Manson JE, Schaumberg DA (2004) A prospective study of serum lipids and risk of diabetic macular edema in type 1 diabetes. Diabetes 53:2883-2892
32. van Hecke MV, Dekker JM, Nijpels G et al (2005) Inflammation and endothelial dysfunction are associated with retinopathy: the Hoorn Study. Diabetologia 48:1300-1306
33. First MR (2004) Tacrolimus based immunosuppression. J Nephrol 17:25-31
34. Allison AC, Eugui EM (2000) Mycophenolate mofetil and its mechanisms of action. Immunopharmacology 47:85-118